 Receptors, GABA-A
"Receptors, GABA-A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and contain an integral membrane chloride channel. Each receptor is assembled as a pentamer from a pool of at least 19 different possible subunits. The receptors belong to a superfamily that share a common CYSTEINE loop.
| Descriptor ID |
D011963
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| MeSH Number(s) |
D12.776.157.530.400.175.562 D12.776.157.530.400.400.100.100 D12.776.543.550.450.175.562 D12.776.543.550.450.500.100.100 D12.776.543.585.400.175.562 D12.776.543.585.400.500.100.100 D12.776.543.750.130.500 D12.776.543.750.720.200.300.300
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| Concept/Terms |
Receptors, GABA-A- Receptors, GABA-A
- Receptors, GABA A
- GABA-A Receptor
- GABA A Receptor
- Receptor, GABA-A
- GABA-A Receptors
- GABA A Receptors
- gamma-Aminobutyric Acid Subtype A Receptors
- gamma Aminobutyric Acid Subtype A Receptors
- Muscimol Receptor
- Receptor, Muscimol
- Receptors, Benzodiazepine-GABA
- Receptors, Benzodiazepine GABA
- Receptors, Muscimol
- Benzodiazepine-GABA Receptor
- Benzodiazepine GABA Receptor
- Receptor, Benzodiazepine-GABA
- GABA-Benzodiazepine Receptor
- GABA Benzodiazepine Receptor
- Receptor, GABA-Benzodiazepine
- GABA-Benzodiazepine Receptors
- GABA Benzodiazepine Receptors
- Benzodiazepine-Gaba Receptors
- Benzodiazepine Gaba Receptors
- Receptors, GABA-Benzodiazepine
- Receptors, GABA Benzodiazepine
- GABA(A) Receptor
- Muscimol Receptors
GABA-A Receptor delta Subunit- GABA-A Receptor delta Subunit
- GABA A Receptor delta Subunit
- delta Subunit, GABA-A Receptor
- delta Subunit, GABA A Receptor
GABA-A Receptor epsilon Subunit- GABA-A Receptor epsilon Subunit
- GABA A Receptor epsilon Subunit
- epsilon Subunit, GABA-A Receptor
- epsilon Subunit, GABA A Receptor
Benzodiazepine Receptor- Benzodiazepine Receptor
- Receptor, Benzodiazepine
- Receptors, Diazepam
- Diazepam Receptor
- Receptor, Diazepam
- Diazepam Receptors
- Benzodiazepine Receptors
- Receptors, Benzodiazepine
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Below are MeSH descriptors whose meaning is more general than "Receptors, GABA-A".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Chloride Channels [D12.776.157.530.400.175]
- Receptors, GABA-A [D12.776.157.530.400.175.562]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.157.530.400.400.100]
- Receptors, GABA-A [D12.776.157.530.400.400.100.100]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Chloride Channels [D12.776.543.550.450.175]
- Receptors, GABA-A [D12.776.543.550.450.175.562]
- Ligand-Gated Ion Channels [D12.776.543.550.450.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.550.450.500.100]
- Receptors, GABA-A [D12.776.543.550.450.500.100.100]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Chloride Channels [D12.776.543.585.400.175]
- Receptors, GABA-A [D12.776.543.585.400.175.562]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.585.400.500.100]
- Receptors, GABA-A [D12.776.543.585.400.500.100.100]
- Receptors, Cell Surface [D12.776.543.750]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.750.130]
- Receptors, GABA-A [D12.776.543.750.130.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Amino Acid [D12.776.543.750.720.200]
- Receptors, GABA [D12.776.543.750.720.200.300]
- Receptors, GABA-A [D12.776.543.750.720.200.300.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, GABA-A".
This graph shows the total number of publications written about "Receptors, GABA-A" by people in this website by year, and whether "Receptors, GABA-A" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 2000 | 1 | 1 | 2 | | 2001 | 1 | 2 | 3 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2007 | 4 | 0 | 4 | | 2008 | 1 | 1 | 2 | | 2009 | 2 | 1 | 3 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 1 | 1 | 2 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 2 | 3 | | 2017 | 1 | 2 | 3 | | 2018 | 1 | 1 | 2 | | 2019 | 1 | 1 | 2 | | 2020 | 3 | 1 | 4 | | 2021 | 2 | 0 | 2 | | 2022 | 1 | 2 | 3 | | 2023 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, GABA-A" by people in Profiles.
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Olah SS, Kareemo DJ, Buchta WC, Sinnen BL, Miller CN, Actor-Engel HS, Gookin SE, Winborn CS, Kleinjan MS, Crosby KC, Aoto J, Smith KR, Kennedy MJ. Acute reorganization of postsynaptic GABAA receptors reveals the functional impact of molecular nanoarchitecture at inhibitory synapses. Cell Rep. 2023 11 28; 42(11):113331.
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Sanderson JL, Freund RK, Castano AM, Benke TA, Dell'Acqua ML. The CaV1.2 G406R mutation decreases synaptic inhibition and alters L-type Ca2+ channel-dependent LTP at hippocampal synapses in a mouse model of Timothy Syndrome. Neuropharmacology. 2022 Dec 01; 220:109271.
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Burlingham SR, Wong NF, Peterkin L, Lubow L, Dos Santos Passos C, Benner O, Ghebrial M, Cast TP, Xu-Friedman MA, S?dhof TC, Chanda S. Induction of synapse formation by de novo neurotransmitter synthesis. Nat Commun. 2022 06 01; 13(1):3060.
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Wu WC, Bradley SP, Christie JM, Pugh JR. Mechanisms and Consequences of Cerebellar Purkinje Cell Disinhibition in a Mouse Model of Duchenne Muscular Dystrophy. J Neurosci. 2022 03 09; 42(10):2103-2115.
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Manzella FM, Covey DF, Jevtovic-Todorovic V, Todorovic SM. Synthetic neuroactive steroids as new sedatives and anaesthetics: Back to the future. J Neuroendocrinol. 2022 02; 34(2):e13086.
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Garcia JD, Gookin SE, Crosby KC, Schwartz SL, Tiemeier E, Kennedy MJ, Dell'Acqua ML, Herson PS, Quillinan N, Smith KR. Stepwise disassembly of GABAergic synapses during pathogenic excitotoxicity. Cell Rep. 2021 12 21; 37(12):110142.
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Troppoli TA, Zanos P, Georgiou P, Gould TD, Rudolph U, Thompson SM. Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at a5 Subunit-Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice. Biol Psychiatry. 2022 08 01; 92(3):216-226.
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McCarthy M, Mak S, Kaufmann CN, Lum HD, Fung CH. Care coordination needs for deprescribing benzodiazepines and benzodiazepine receptor agonists. Res Social Adm Pharm. 2022 04; 18(4):2691-2694.
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Hoehne A, McFadden MH, DiGregorio DA. Feed-forward recruitment of electrical synapses enhances synchronous spiking in the mouse cerebellar cortex. Elife. 2020 09 29; 9.
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Rajgor D, Purkey AM, Sanderson JL, Welle TM, Garcia JD, Dell'Acqua ML, Smith KR. Local miRNA-Dependent Translational Control of GABAAR Synthesis during Inhibitory Long-Term Potentiation. Cell Rep. 2020 06 23; 31(12):107785.
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