 Trypsin
"Trypsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine endopeptidase that is formed from TRYPSINOGEN in the pancreas. It is converted into its active form by ENTEROPEPTIDASE in the small intestine. It catalyzes hydrolysis of the carboxyl group of either arginine or lysine. EC 3.4.21.4.
| Descriptor ID |
D014357
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| MeSH Number(s) |
D08.811.277.656.300.760.895 D08.811.277.656.959.350.895
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Trypsin".
Below are MeSH descriptors whose meaning is more specific than "Trypsin".
This graph shows the total number of publications written about "Trypsin" by people in this website by year, and whether "Trypsin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 2001 | 1 | 1 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 2 | 2 | | 2004 | 3 | 3 | 6 | | 2006 | 1 | 3 | 4 | | 2008 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 1 | 1 | 2 | | 2013 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2018 | 1 | 1 | 2 | | 2021 | 1 | 1 | 2 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Trypsin" by people in Profiles.
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McCabe MC, Gejji V, Barnebey A, Siuzdak G, Hoang LT, Pham T, Larson KY, Saviola AJ, Yannone SM, Hansen KC. From volcanoes to the bench: Advantages of novel hyperthermoacidic archaeal proteases for proteomics workflows. J Proteomics. 2023 10 30; 289:104992.
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Borovsky D, Roug? P. Heliothis virescens chymotrypsin is translationally controlled by AeaTMOF binding ABC putative receptor. Arch Insect Biochem Physiol. 2023 Oct; 114(2):1-24.
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Borovsky D, Roug? P, Shatters RG. The Ribosome Is the Ultimate Receptor for Trypsin Modulating Oostatic Factor (TMOF). Biomolecules. 2022 04 14; 12(4).
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Zanotto GM, Liesbeny P, Barrett M, Zlotnick H, Frank E, Grodzinsky AJ, Frisbie DD. Microfracture Augmentation With Trypsin Pretreatment and Growth Factor-Functionalized Self-assembling Peptide Hydrogel Scaffold in an Equine Model. Am J Sports Med. 2021 07; 49(9):2498-2508.
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Morrison EA, Baweja L, Poirier MG, Wereszczynski J, Musselman CA. Nucleosome composition regulates the histone H3 tail conformational ensemble and accessibility. Nucleic Acids Res. 2021 05 07; 49(8):4750-4767.
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Takahashi K, Banda NK, Holers VM, Van Cott EM. Complement component factor B has thrombin-like activity. Biochem Biophys Res Commun. 2021 05 07; 552:17-22.
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Liebesny PH, Mroszczyk K, Zlotnick H, Hung HH, Frank E, Kurz B, Zanotto G, Frisbie D, Grodzinsky AJ. Enzyme Pretreatment plus Locally Delivered HB-IGF-1 Stimulate Integrative Cartilage Repair In Vitro. Tissue Eng Part A. 2019 09; 25(17-18):1191-1201.
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Zanotto G, Liebesny P, Barrett M, Zlotnick H, Grodzinsky A, Frisbie D. Trypsin Pre-Treatment Combined With Growth Factor Functionalized Self-Assembling Peptide Hydrogel Improves Cartilage Repair in Rabbit Model. J Orthop Res. 2019 11; 37(11):2307-2315.
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Borovsky D, Hancock RG, Roug? P, Powell CA, Shatters RG. Juvenile hormone affects the splicing of Culex quinquefasciatus early trypsin messenger RNA. Arch Insect Biochem Physiol. 2018 Nov; 99(3):e21506.
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Reisdorph R, Littrell-Miller B, Powell R, Reisdorph N. A mass spectrometry based predictive strategy reveals ADAP1 is phosphorylated at tyrosine 364. Rapid Commun Mass Spectrom. 2018 Aug 15; 32(15):1173-1180.
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