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Deubiquitinating Enzyme CYLD

"Deubiquitinating Enzyme CYLD" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A deubiquitinase and tumor-suppressor protein that specifically cleaves LYSINE-63-linked polyubiquitin chains and also has endodeubiquitinase activity. It functions to regulate NF-KAPPA B and WNT SIGNALING PATHWAY activity, contributing to cell survival, proliferation, and differentiation. Mutations in the CYLD gene are associated with cases of FAMILIAL CYLINDROMATOSIS.


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This graph shows the total number of publications written about "Deubiquitinating Enzyme CYLD" by people in this website by year, and whether "Deubiquitinating Enzyme CYLD" was a major or minor topic of these publications.
Bar chart showing 2 publications over 1 distinct years, with a maximum of 2 publications in 2014
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