 Crohn Disease
"Crohn Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Descriptor ID |
D003424
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| MeSH Number(s) |
C06.405.205.731.500 C06.405.469.432.500
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| Concept/Terms |
Crohn Disease- Crohn Disease
- Crohn's Enteritis
- Regional Enteritis
- Crohn's Disease
- Crohns Disease
- Inflammatory Bowel Disease 1
Ileitis, Terminal- Ileitis, Terminal
- Terminal Ileitis
- Ileitis, Regional
- Regional Ileitides
- Regional Ileitis
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Below are MeSH descriptors whose meaning is more general than "Crohn Disease".
Below are MeSH descriptors whose meaning is more specific than "Crohn Disease".
This graph shows the total number of publications written about "Crohn Disease" by people in this website by year, and whether "Crohn Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 0 | 2 | 2 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 1 | 2 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 1 | 2 | | 2005 | 1 | 1 | 2 | | 2006 | 1 | 2 | 3 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 1 | 2 | | 2009 | 2 | 1 | 3 | | 2010 | 3 | 1 | 4 | | 2011 | 2 | 0 | 2 | | 2012 | 1 | 2 | 3 | | 2013 | 5 | 3 | 8 | | 2014 | 8 | 0 | 8 | | 2015 | 5 | 2 | 7 | | 2016 | 6 | 2 | 8 | | 2017 | 7 | 2 | 9 | | 2018 | 3 | 1 | 4 | | 2019 | 7 | 1 | 8 | | 2020 | 15 | 0 | 15 | | 2021 | 12 | 3 | 15 | | 2022 | 16 | 0 | 16 | | 2023 | 12 | 0 | 12 | | 2024 | 9 | 2 | 11 | | 2025 | 4 | 0 | 4 |
To return to the timeline, click here.
Below are the most recent publications written about "Crohn Disease" by people in Profiles.
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Jacobsen GE, Gonzalez EE, Mendygral P, Faust KM, Hazime H, Fernandez I, Santander AM, Quintero MA, Jiang C, Damas OM, Deshpande AR, Kerman DH, Proksell S, Sendzischew Shane M, Sussman DA, Ghaddar B, Cickovsk T, Abreu MT. Deep Sequencing of Crohn's Disease Lamina Propria Phagocytes Identifies Pathobionts and Correlates With Pro-Inflammatory Gene Expression. Inflamm Bowel Dis. 2025 May 12; 31(5):1203-1219.
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Joseph A, Bachour SP, Shah R, El Halabi J, Syed H, Lyu R, Cohen B, Rieder F, Achkar JP, Philpott J, Qazi T, Hull T, Lipman J, Wexner S, Holubar SD, Regueiro M, Click B. Postoperative Crohn's Disease Recurrence Risk and Optimal Biologic Timing After Temporary Diversion Following Ileocolic Resection. Inflamm Bowel Dis. 2025 Mar 03; 31(3):686-695.
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Ahmad H, Click B, Morris HL, Crawford JM, Choi J, Long MD. Factors Predicting Loss of Remission in Crohn's Disease Patients in Endoscopic Remission in the Real World: Results From TARGET-IBD. J Clin Gastroenterol. 2025 Mar 01; 59(3):245-250.
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Mitchel EB, Dolinger MT, Constant B, Wang Z, Guisado D, Gao M, Fusillo S, Baldassano RN, Kelsen J, Dubinsky M, Huang J, Albenberg L. Ustekinumab is safe and effective in pediatric patients with Crohn's disease. J Pediatr Gastroenterol Nutr. 2025 Apr; 80(4):653-663.
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Ziegler O, Moyer AM, Park JH, Quattrone M, Kulaylat AS, Deutsch MJ, Jeganathan NA, Koltun WA, Scow JS. Low Rates of Short-Term Anastomotic Complications After Kono-S versus Side-to-Side Stapled Anastomosis. J Surg Res. 2024 Dec; 304:74-80.
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Levi Mortera S, Marzano V, Rapisarda F, Marangelo C, Pirona I, Vernocchi P, Di Michele M, Del Chierico F, Quintero MA, Fernandez I, Hazime H, Killian RM, Solis N, Ortega M, Damas OM, Proksell S, Kerman DH, Deshpande AR, Garces L, Scaldaferri F, Gasbarrini A, Abreu MT, Putignani L. Metaproteomics reveals diet-induced changes in gut microbiome function according to Crohn's disease location. Microbiome. 2024 Oct 23; 12(1):217.
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Thomas T, Friedrich M, Rich-Griffin C, Pohin M, Agarwal D, Pakpoor J, Lee C, Tandon R, Rendek A, Aschenbrenner D, Jainarayanan A, Voda A, Siu JHY, Sanches-Peres R, Nee E, Sathananthan D, Kotliar D, Todd P, Kiourlappou M, Gartner L, Ilott N, Issa F, Hester J, Turner J, Nayar S, Mackerodt J, Zhang F, Jonsson A, Brenner M, Raychaudhuri S, Kulicke R, Ramsdell D, Stransky N, Pagliarini R, Bielecki P, Spies N, Marsden B, Taylor S, Wagner A, Klenerman P, Walsh A, Coles M, Jostins-Dean L, Powrie FM, Filer A, Travis S, Uhlig HH, Dendrou CA, Buckley CD. A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease. Nat Immunol. 2024 Nov; 25(11):2152-2165.
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Bachour SP, Shah RS, Joseph A, Syed H, Ali AH, Rieder F, Barnes EL, Axelrad J, Holubar SD, Regueiro M, Cohen BL, Click BH. Change in Biologic Class Promotes Endoscopic Remission Following Endoscopic Postoperative Crohn's Disease Recurrence. J Clin Gastroenterol. 2024 Sep 01; 58(8):810-817.
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Honan AM, Jacobsen GE, Drum H, Vazquez EN, Quintero MA, Deshpande AR, Sussman DA, Kerman DH, Damas OM, Proksell S, Van der Jeught K, Abreu MT, Chen Z. Stromal-Like Cells Are Found in Peripheral Blood of Patients With Inflammatory Bowel Disease and Correlate With Immune Activation State. Clin Transl Gastroenterol. 2024 Sep 01; 15(9):e1.
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Li J, Simmons AJ, Hawkins CV, Chiron S, Ramirez-Solano MA, Tasneem N, Kaur H, Xu Y, Revetta F, Vega PN, Bao S, Cui C, Tyree RN, Raber LW, Conner AN, Pilat JM, Jacobse J, McNamara KM, Allaman MM, Raffa GA, Gobert AP, Asim M, Goettel JA, Choksi YA, Beaulieu DB, Dalal RL, Horst SN, Pabla BS, Huo Y, Landman BA, Roland JT, Scoville EA, Schwartz DA, Washington MK, Shyr Y, Wilson KT, Coburn LA, Lau KS, Liu Q. Identification and multimodal characterization of a specialized epithelial cell type associated with Crohn's disease. Nat Commun. 2024 Aug 22; 15(1):7204.
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