 Crohn Disease
"Crohn Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Descriptor ID |
D003424
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| MeSH Number(s) |
C06.405.205.731.500 C06.405.469.432.500
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| Concept/Terms |
Crohn Disease- Crohn Disease
- Crohn's Enteritis
- Regional Enteritis
- Crohn's Disease
- Crohns Disease
- Inflammatory Bowel Disease 1
Ileitis, Terminal- Ileitis, Terminal
- Terminal Ileitis
- Ileitis, Regional
- Regional Ileitides
- Regional Ileitis
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Below are MeSH descriptors whose meaning is more general than "Crohn Disease".
Below are MeSH descriptors whose meaning is more specific than "Crohn Disease".
This graph shows the total number of publications written about "Crohn Disease" by people in this website by year, and whether "Crohn Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 1 | 2 | 3 | | 1998 | 2 | 0 | 2 | | 1999 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 1 | 2 | | 2006 | 1 | 2 | 3 | | 2007 | 1 | 0 | 1 | | 2008 | 3 | 1 | 4 | | 2009 | 4 | 1 | 5 | | 2010 | 3 | 1 | 4 | | 2011 | 2 | 0 | 2 | | 2012 | 2 | 3 | 5 | | 2013 | 5 | 3 | 8 | | 2014 | 7 | 0 | 7 | | 2015 | 5 | 2 | 7 | | 2016 | 6 | 2 | 8 | | 2017 | 11 | 2 | 13 | | 2018 | 5 | 1 | 6 | | 2019 | 11 | 2 | 13 | | 2020 | 19 | 0 | 19 | | 2021 | 16 | 3 | 19 | | 2022 | 20 | 0 | 20 | | 2023 | 13 | 0 | 13 | | 2024 | 10 | 2 | 12 | | 2025 | 11 | 0 | 11 | | 2026 | 3 | 0 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Crohn Disease" by people in Profiles.
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Denton KH, Slaughter JC, Bennett A, Scoville EA, Dalal RL, Horst S, Beaulieu DB, Schwartz DA, Pabla BS. Patient Perspectives of Intestinal Ultrasound in IBD: A Quantitative Evaluation of Satisfaction and Diagnostic Preference. Dig Dis Sci. 2026 Oct; 71(10):5063-5070.
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Li Q, Nambu R, Yaqiang H, Shen X, Argmann C, Guan R, Janssen E, Le Voyer T, Warner N, Yu DD, Guo J, Long K, Ouahed J, Field M, Collen L, Bibus J, Illig D, Rohlfs M, Yu Z, Yang S, Li W, Platt CD, Comella PH, Jordan D, Suárez-Fariñas M, Alosaimi MF, Peters LA, Rosain J, Fieschi C, Puel A, Hsieh EWY, Naito T, Zeng Z, Rodríguez-Belvís MV, Palomino L, Küster P, Li D, Klein C, Snapper SB, Casanova JL, Geha R, Hoffenberg E, McGovern DPB, Schadt E, Kotlarz D, Li D, Muise AM. BIRC3 (Encoding cIAP2) Variants Result in Dysregulated RIPK1 Signaling Leading to Increased Epithelial Cell Death and Are Associated With Monogenic Crohn's Disease. Gastroenterology. 2026 Nov; 171(5):885-901.
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Raffa GA, Tyree RN, Carson K, Allaman MM, Beaulieu DB, Dalal RL, Pabla BS, Scoville EA, Horst SN, Schwartz DA, Washington MK, Wilson KT, Coburn LA. Non-invasive determination of disease activity in Crohn's disease by serum luminex profiling. Sci Rep. 2026 Mar 09; 16(1).
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Huey LM, Rosenzweig HL, Napier RJ. Resolving the field: a role for Nod2 in T cells. J Immunol. 2025 Dec 01; 214(12):3188-3198.
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Scott FI, Ananthakrishnan AN, Click B, Agrawal M, Syal G, Haydek JP, Yuan Y, Kappelman MD, Lewis JD, Singh S. AGA Living Clinical Practice Guideline on the Pharmacologic Management of Moderate-to-Severe Crohn's Disease. Gastroenterology. 2025 12; 169(7):1397-1448.
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Singh S, Murad MH, Yuan Y, Ananthakrishnan AN, Click B, Syal G, Haydek JP, Agrawal M, Kappelman MD, Lewis JD, Scott FI. Comparative Efficacy of Advanced Therapies for Management of Moderate-to-Severe Crohn's Disease: 2025 AGA Evidence Synthesis. Gastroenterology. 2025 12; 169(7):1516-1536.
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Chambers CD, Johnson DL, Luo Y, Xu R, Adam MP, Braddock SR, Jones KL. Birth Outcomes in Women Who Have Taken Vedolizumab in Pregnancy: Results From the Vedolizumab Pregnancy Exposure Registry. Am J Gastroenterol. 2026 Mar 01; 121(3):720-732.
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Pothula SR, Regueiro M, Click BH. Advancements in the prevention and management of postoperative Crohn's disease recurrence. Expert Rev Gastroenterol Hepatol. 2025 Jul; 19(7):711-723.
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Jacobsen GE, Gonzalez EE, Mendygral P, Faust KM, Hazime H, Fernandez I, Santander AM, Quintero MA, Jiang C, Damas OM, Deshpande AR, Kerman DH, Proksell S, Sendzischew Shane M, Sussman DA, Ghaddar B, Cickovsk T, Abreu MT. Deep Sequencing of Crohn's Disease Lamina Propria Phagocytes Identifies Pathobionts and Correlates With Pro-Inflammatory Gene Expression. Inflamm Bowel Dis. 2025 May 12; 31(5):1203-1219.
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Joseph A, Bachour SP, Shah R, El Halabi J, Syed H, Lyu R, Cohen B, Rieder F, Achkar JP, Philpott J, Qazi T, Hull T, Lipman J, Wexner S, Holubar SD, Regueiro M, Click B. Postoperative Crohn's Disease Recurrence Risk and Optimal Biologic Timing After Temporary Diversion Following Ileocolic Resection. Inflamm Bowel Dis. 2025 03 03; 31(3):686-695.
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