Minichromosome Maintenance Complex Component 7
"Minichromosome Maintenance Complex Component 7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It is also found in tightly-bound trimeric complex with MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 4 and MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 6.
| Descriptor ID |
D064168
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| MeSH Number(s) |
D08.811.277.040.025.159.186.700 D08.811.399.340.186.700 D12.776.167.409.700 D12.776.660.235.500.700 D12.776.664.235.750.700
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Minichromosome Maintenance Complex Component 7".
Below are MeSH descriptors whose meaning is more specific than "Minichromosome Maintenance Complex Component 7".
This graph shows the total number of publications written about "Minichromosome Maintenance Complex Component 7" by people in this website by year, and whether "Minichromosome Maintenance Complex Component 7" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2000 | 0 | 2 | 2 | | 2006 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Minichromosome Maintenance Complex Component 7" by people in Profiles.
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Bolhuis DL, Fleifel D, Bonacci T, Wang X, Mouery BL, Cook JG, Brown NG, Emanuele MJ. USP37 prevents unscheduled replisome unloading through MCM complex deubiquitination. Nat Commun. 2025 May 16; 16(1):4575.
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Gaggioli V, Le Viet B, Germe T, Hyrien O. DNA topoisomerase IIa controls replication origin cluster licensing and firing time in Xenopus egg extracts. Nucleic Acids Res. 2013 Aug; 41(15):7313-31.
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Chen X, Liu G, Leffak M. Activation of a human chromosomal replication origin by protein tethering. Nucleic Acids Res. 2013 Jul; 41(13):6460-74.
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Thangavel C, Boopathi E, Ertel A, Lim M, Addya S, Fortina P, Witkiewicz AK, Knudsen ES. Regulation of miR106b cluster through the RB pathway: mechanism and functional targets. Cell Cycle. 2013 Jan 01; 12(1):98-111.
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Ghosh M, Kemp M, Liu G, Ritzi M, Schepers A, Leffak M. Differential binding of replication proteins across the human c-myc replicator. Mol Cell Biol. 2006 Jul; 26(14):5270-83.
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Honeycutt KA, Chen Z, Koster MI, Miers M, Nuchtern J, Hicks J, Roop DR, Shohet JM. Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis. Oncogene. 2006 Jul 06; 25(29):4027-32.
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Tye BK, Sawyer S. The hexameric eukaryotic MCM helicase: building symmetry from nonidentical parts. J Biol Chem. 2000 Nov 10; 275(45):34833-6.
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Homesley L, Lei M, Kawasaki Y, Sawyer S, Christensen T, Tye BK. Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins. Genes Dev. 2000 Apr 15; 14(8):913-26.
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