Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Chun Wan

TitleResearch Associate
InstitutionUniversity of Colorado Boulder
DepartmentBiology-MCD Instruction

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wu J, Wan C, Tian Y, Ouyang Y, Puscher H, Li S, Yin Q, Shen J. Bi-handed assembly chaperones regulate protein complex assembly through an intramolecular handover mechanism. Sci Adv. 2025 Sep 12; 11(37):eadw9158. PMID: 40938986.
      View in: PubMed
    2. Squiers GT, Wan C, Gorder J, Puscher H, Shen J. A Commander-independent function of COMMD3 in endosomal trafficking. Elife. 2025 Aug 21; 14. PMID: 40838988.
      View in: PubMed
    3. Squiers GT, Wan C, Gorder J, Puscher H, Shen J. A Commander-independent function of COMMD3 in endosomal trafficking. bioRxiv. 2025 Apr 01. PMID: 39763841.
      View in: PubMed
    4. Shen Z, Wang Y, Gao J, Gu W, Ren Z, Xu L, Qian R, Miao Q, Hu X, Wu Y, Liu W, Cai Y, Wan CC, Zhu Y, Sun L, Yan T. The EZH2/MCM Complex/hTERT axis facilitates hepatocellular carcinoma progression by inhibiting cellular senescence. Mech Ageing Dev. 2025 Apr; 224:112040. PMID: 39933657.
      View in: PubMed
    5. Wang Y, Gao J, Ren Z, Shen Z, Gu W, Miao Q, Hu X, Wu Y, Liu W, Jia J, Cai Y, Wan CC, Sun L, Yan T. A pan-cancer analysis of homeobox family: expression characteristics and latent significance in prognosis and immune microenvironment. Front Oncol. 2025; 15:1521652. PMID: 39980564.
      View in: PubMed
    6. Gu W, Li H, Sun L, Shen Z, Wang Y, Hu X, Wu Y, Liu W, Wan CC, Cai Y, Yan T. The RNA-binding protein CMSS1 promotes the progression of non-small cell lung cancer by regulating the telomerase protein subunit hTERT. Life Sci. 2025 Jan 15; 361:123321. PMID: 39710061.
      View in: PubMed
    7. Wan C, Puscher H, Ouyang Y, Wu J, Tian Y, Li S, Yin Q, Shen J. An AAGAB-to-CCDC32 handover mechanism controls the assembly of the AP2 adaptor complex. Proc Natl Acad Sci U S A. 2024 Aug 20; 121(34):e2409341121. PMID: 39145939.
      View in: PubMed
    8. Shen Z, Wang Y, Wang G, Gu W, Zhao S, Hu X, Liu W, Cai Y, Ma Z, Gautam RK, Jia J, Wan CC, Yan T. Research progress of small-molecule drugs in targeting telomerase in human cancer and aging. Chem Biol Interact. 2023 Sep 01; 382:110631. PMID: 37451664.
      View in: PubMed
    9. Yin Q, Zhang X, Liao S, Huang X, Wan CC, Wang Y. Potential anticoagulant of traditional chinese medicine and novel targets for anticoagulant drugs. Phytomedicine. 2023 Jul 25; 116:154880. PMID: 37267694.
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    10. Wang S, Chen X, Crisman L, Dou X, Winborn CS, Wan C, Puscher H, Yin Q, Kennedy MJ, Shen J. Regulation of cargo exocytosis by a Reps1-Ralbp1-RalA module. Sci Adv. 2023 02 22; 9(8):eade2540. PMID: 36812304.
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    11. Yao L, Zhang X, Huang C, Cai Y, Wan CC. The Effect of Citrus aurantium on Non-Small-Cell Lung Cancer: A Research Based on Network and Experimental Pharmacology. Biomed Res Int. 2023; 2023:6407588. PMID: 36726839.
      View in: PubMed
    12. Wan C, Stowell MHB, Shen J. Progress and gaps of extracellular vesicle-mediated intercellular cargo transfer in the central nervous system. Commun Biol. 2022 11 11; 5(1):1223. PMID: 36369335.
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    13. Lin Z, Wang G, Gu W, Zhao S, Shen Z, Liu W, Zheng G, Chen B, Cai Y, Li M, Wan CC, Yan T. Exploration of the Protective Mechanism of Naringin in the Acetaminophen-Induced Hepatic Injury by Metabolomics. Oxid Med Cell Longev. 2022; 2022:7138194. PMID: 36160708.
      View in: PubMed
    14. Chen K, Shen Z, Wang G, Gu W, Zhao S, Lin Z, Liu W, Cai Y, Mushtaq G, Jia J, Wan CC, Yan T. Research progress of CRISPR-based biosensors and bioassays for molecular diagnosis. Front Bioeng Biotechnol. 2022; 10:986233. PMID: 36185462.
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    15. Yao L, Liu W, Bashir M, Nisar MF, Wan CC. Eriocitrin: A review of pharmacological effects. Biomed Pharmacother. 2022 Oct; 154:113563. PMID: 35987162.
      View in: PubMed
    16. Das R, Rauf A, Mitra S, Emran TB, Hossain MJ, Khan Z, Naz S, Ahmad B, Meyyazhagan A, Pushparaj K, Wan CC, Balasubramanian B, Rengasamy KR, Simal-Gandara J. Therapeutic potential of marine macrolides: An overview from 1990 to 2022. Chem Biol Interact. 2022 Sep 25; 365:110072. PMID: 35952775.
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    17. Cai Y, Huang C, Zhou M, Xu S, Xie Y, Gao S, Yang Y, Deng Z, Zhang L, Shu J, Yan T, Wan CC. Role of curcumin in the treatment of acute kidney injury: research challenges and opportunities. Phytomedicine. 2022 Sep; 104:154306. PMID: 35809376.
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    18. Gu W, Lin Z, Zhao S, Wang G, Shen Z, Liu W, Cai Y, Wang K, Wan CC, Yan T. Research Progress on G-Quadruplexes in Human Telomeres and Human Telomerase Reverse Transcriptase (hTERT) Promoter. Oxid Med Cell Longev. 2022; 2022:2905663. PMID: 35707279.
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    19. Ondrasek G, Rathod S, Manohara KK, Gireesh C, Anantha MS, Sakhare AS, Parmar B, Yadav BK, Bandumula N, Raihan F, Zielinska-Chmielewska A, Meriño-Gergichevich C, Reyes-Díaz M, Khan A, Panfilova O, Seguel Fuentealba A, Romero SM, Nabil B, Wan CC, Shepherd J, Horvatinec J. Salt Stress in Plants and Mitigation Approaches. Plants (Basel). 2022 Mar 08; 11(6). PMID: 35336599.
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    20. Wan C, Crisman L, Wang B, Tian Y, Wang S, Yang R, Datta I, Nomura T, Li S, Yu H, Yin Q, Shen J. AAGAB is an assembly chaperone regulating AP1 and AP2 clathrin adaptors. J Cell Sci. 2021 10 01; 134(19). PMID: 34494650.
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    21. Nisar MF, Yousaf M, Saleem M, Khalid H, Niaz K, Yaqub M, Waqas MY, Ahmed A, Abaid-Ullah M, Chen J, Chen C, Rengasamy KRR, Wan CC. Development of Iron Sequester Antioxidant Quercetin@ZnO Nanoparticles with Photoprotective Effects on UVA-Irradiated HaCaT Cells. Oxid Med Cell Longev. 2021; 2021:6072631. PMID: 34484566.
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    22. Liu Y, Wan C, Rathore SS, Stowell MHB, Yu H, Shen J. SNARE Zippering Is Suppressed by a Conformational Constraint that Is Removed by v-SNARE Splitting. Cell Rep. 2021 01 12; 34(2):108611. PMID: 33440145.
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    23. Dombach JL, Quintana JLJ, Nagy TA, Wan C, Crooks AL, Yu H, Su CC, Yu EW, Shen J, Detweiler CS. A small molecule that mitigates bacterial infection disrupts Gram-negative cell membranes and is inhibited by cholesterol and neutral lipids. PLoS Pathog. 2020 12; 16(12):e1009119. PMID: 33290418.
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    24. Zhang X, Xu Q, Zi Z, Liu Z, Wan C, Crisman L, Shen J, Liu X. Programmable Extracellular Vesicles for Macromolecule Delivery and Genome Modifications. Dev Cell. 2020 12 21; 55(6):784-801.e9. PMID: 33296682.
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    25. Wang S, Liu Y, Crisman L, Wan C, Miller J, Yu H, Shen J. Genetic evidence for an inhibitory role of tomosyn in insulin-stimulated GLUT4 exocytosis. Traffic. 2020 10; 21(10):636-646. PMID: 32851733.
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    26. Yang C, Chen F, Ren P, Lofchy L, Wan C, Shen J, Wang G, Gaikwad H, Ponder J, Jordan CT, Scheinman R, Simberg D. Delivery of a model lipophilic membrane cargo to bone marrow via cell-derived microparticles. J Control Release. 2020 10 10; 326:324-334. PMID: 32682903.
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    27. Rathore SS, Liu Y, Yu H, Wan C, Lee M, Yin Q, Stowell MHB, Shen J. Intracellular Vesicle Fusion Requires a Membrane-Destabilizing Peptide Located at the Juxtamembrane Region of the v-SNARE. Cell Rep. 2019 12 24; 29(13):4583-4592.e3. PMID: 31875562.
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    28. Gulbranson DR, Crisman L, Lee M, Ouyang Y, Menasche BL, Demmitt BA, Wan C, Nomura T, Ye Y, Yu H, Shen J. AAGAB Controls AP2 Adaptor Assembly in Clathrin-Mediated Endocytosis. Dev Cell. 2019 08 19; 50(4):436-446.e5. PMID: 31353312.
      View in: PubMed
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