Discoidin Domain
"Discoidin Domain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein domain originally identified in DISCOIDINS. It occurs in a variety of unrelated proteins in multicellular organisms, where it recognizes different ligands with distinct biological functions. Structurally, it consists of two antiparallel beta sheets that form a "jellyroll" configuration stabilized by two intramolecular disulfide bonds. Sequence differences within this module determine ligand specificity; in DISCOIDIN DOMAIN RECEPTORS, it binds to FIBRILLAR COLLAGENS and NON-FIBRILLAR COLLAGENS.
| Descriptor ID |
D000070822
|
| MeSH Number(s) |
G02.111.570.820.709.275.750.219
|
| Concept/Terms |
Discoidin Domain- Discoidin Domain
- Domain, Discoidin
- Domains, Discoidin
- Discoidin Domains
|
Below are MeSH descriptors whose meaning is more general than "Discoidin Domain".
Below are MeSH descriptors whose meaning is more specific than "Discoidin Domain".
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