Methyl CpG Binding Domain
"Methyl CpG Binding Domain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein domain of about 70 amino acids in length that folds into a sandwich structure consisting of a beta sheet, alpha helix, and C-terminal hairpin loop which forms a hydrophobic methylated-DNA binding patch. It binds to methylated CPG ISLANDS in eukaryotes and occurs with other DNA and CHROMATIN binding domains such as AT-HOOK MOTIFS in eukaryotic DNA BINDING PROTEINS.
| Descriptor ID |
D000070593
|
| MeSH Number(s) |
G02.111.570.820.709.275.750.438
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Methyl CpG Binding Domain".
Below are MeSH descriptors whose meaning is more specific than "Methyl CpG Binding Domain".
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Below are the most recent publications written about "Methyl CpG Binding Domain" by people in Profiles.