 Keratins
"Keratins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
| Descriptor ID |
D007633
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| MeSH Number(s) |
D05.750.078.593.450 D12.776.220.475.450 D12.776.860.607
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Keratins".
Below are MeSH descriptors whose meaning is more specific than "Keratins".
This graph shows the total number of publications written about "Keratins" by people in this website by year, and whether "Keratins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 7 | 9 | | 1996 | 2 | 1 | 3 | | 1997 | 1 | 0 | 1 | | 1998 | 3 | 3 | 6 | | 1999 | 6 | 2 | 8 | | 2000 | 3 | 2 | 5 | | 2001 | 2 | 2 | 4 | | 2002 | 1 | 1 | 2 | | 2003 | 1 | 3 | 4 | | 2004 | 1 | 3 | 4 | | 2005 | 2 | 2 | 4 | | 2006 | 2 | 4 | 6 | | 2007 | 2 | 2 | 4 | | 2008 | 1 | 3 | 4 | | 2010 | 1 | 1 | 2 | | 2012 | 0 | 3 | 3 | | 2013 | 0 | 2 | 2 | | 2014 | 1 | 2 | 3 | | 2015 | 2 | 1 | 3 | | 2016 | 0 | 1 | 1 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Keratins" by people in Profiles.
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Lindholm KE, Moran CA. Primary Mammary-Like Carcinoma of the Lung: A Case Report of a Distinct Type of Primary Lung Carcinoma. Int J Surg Pathol. 2020 Sep; 28(6):663-667.
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Leung DYM, Calatroni A, Zaramela LS, LeBeau PK, Dyjack N, Brar K, David G, Johnson K, Leung S, Ramirez-Gama M, Liang B, Rios C, Montgomery MT, Richers BN, Hall CF, Norquest KA, Jung J, Bronova I, Kreimer S, Talbot CC, Crumrine D, Cole RN, Elias P, Zengler K, Seibold MA, Berdyshev E, Goleva E. The nonlesional skin surface distinguishes atopic dermatitis with food allergy as a unique endotype. Sci Transl Med. 2019 02 20; 11(480).
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Lindholm KE, Kalhor N, Moran CA. Osteoclast-like giant cell-rich carcinomas of the lung: a clinicopathological, immunohistochemical, and molecular study of 3 cases. Hum Pathol. 2019 03; 85:168-173.
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Greer RO, Eskendri J, Freedman P, Ahmadian M, Murakami-Walter A, Varella-Garcia M. Assessment of biologically aggressive, recurrent glandular odontogenic cysts for mastermind-like 2 (MAML2) rearrangements: histopathologic and fluorescent in situ hybridization (FISH) findings in 11 cases. J Oral Pathol Med. 2018 Feb; 47(2):192-197.
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Wang G, Benasutti H, Jones JF, Shi G, Benchimol M, Pingle S, Kesari S, Yeh Y, Hsieh LE, Liu YT, Elias A, Simberg D. Isolation of Breast cancer CTCs with multitargeted buoyant immunomicrobubbles. Colloids Surf B Biointerfaces. 2018 Jan 01; 161:200-209.
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Futia GL, Schlaepfer IR, Qamar L, Behbakht K, Gibson EA. Statistical performance of image cytometry for DNA, lipids, cytokeratin, & CD45 in a model system for circulation tumor cell detection. Cytometry A. 2017 07; 91(7):662-674.
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Liu Y, Snedecor ER, Zhang X, Xu Y, Huang L, Jones EC, Zhang L, Clark RA, Roop DR, Qin C, Chen J. Correction of Hair Shaft Defects through Allele-Specific Silencing of Mutant Krt75. J Invest Dermatol. 2016 Jan; 136(1):45-51.
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Kumar V, Bouameur JE, B?r J, Rice RH, Hornig-Do HT, Roop DR, Schwarz N, Brodesser S, Thiering S, Leube RE, Wiesner RJ, Vijayaraj P, Brazel CB, Heller S, Binder H, L?ffler-Wirth H, Seibel P, Magin TM. A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 07; 211(5):1057-75.
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Cao YA, Hickerson RP, Seegmiller BL, Grapov D, Gross MM, Bessette MR, Phinney BS, Flores MA, Speaker TJ, Vermeulen A, Bravo AA, Bruckner AL, Milstone LM, Schwartz ME, Rice RH, Kaspar RL. Gene expression profiling in pachyonychia congenita skin. J Dermatol Sci. 2015 Mar; 77(3):156-65.
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Schowinsky JT, Ormond DR, Kleinschmidt-DeMasters BK. Tibial adamantinoma: late metastasis to the brain. J Neuropathol Exp Neurol. 2015 Jan; 74(1):95-7.
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