Mutagenesis
"Mutagenesis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Process of generating a genetic MUTATION. It may occur spontaneously or be induced by MUTAGENS.
Descriptor ID |
D016296
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MeSH Number(s) |
G05.558
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mutagenesis".
Below are MeSH descriptors whose meaning is more specific than "Mutagenesis".
This graph shows the total number of publications written about "Mutagenesis" by people in this website by year, and whether "Mutagenesis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 4 | 4 | 1995 | 0 | 2 | 2 | 1996 | 0 | 3 | 3 | 1997 | 1 | 3 | 4 | 1998 | 0 | 8 | 8 | 1999 | 1 | 3 | 4 | 2000 | 0 | 3 | 3 | 2001 | 0 | 6 | 6 | 2002 | 0 | 3 | 3 | 2003 | 2 | 5 | 7 | 2004 | 1 | 4 | 5 | 2005 | 1 | 1 | 2 | 2006 | 0 | 4 | 4 | 2007 | 1 | 1 | 2 | 2008 | 1 | 2 | 3 | 2009 | 0 | 6 | 6 | 2010 | 0 | 1 | 1 | 2011 | 0 | 6 | 6 | 2012 | 1 | 2 | 3 | 2013 | 0 | 7 | 7 | 2014 | 0 | 2 | 2 | 2015 | 2 | 5 | 7 | 2016 | 2 | 2 | 4 | 2017 | 1 | 5 | 6 | 2018 | 2 | 4 | 6 | 2019 | 0 | 3 | 3 | 2020 | 1 | 5 | 6 | 2021 | 1 | 6 | 7 | 2022 | 1 | 2 | 3 | 2023 | 0 | 3 | 3 |
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Below are the most recent publications written about "Mutagenesis" by people in Profiles.
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Daffern N, Francino-Urdaniz IM, Baumer ZT, Whitehead TA. Standardizing cassette-based deep mutagenesis by Golden Gate assembly. Biotechnol Bioeng. 2024 01; 121(1):281-290.
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Shee S, Veetil RT, Mohanraj K, Das M, Malhotra N, Bandopadhyay D, Beig H, Birua S, Niphadkar S, Nagarajan SN, Sinha VK, Thakur C, Rajmani RS, Chandra N, Laxman S, Singh M, Samal A, Seshasayee AN, Singh A. Biosensor-integrated transposon mutagenesis reveals rv0158 as a coordinator of redox homeostasis in Mycobacterium tuberculosis. Elife. 2023 08 29; 12.
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Lee E, Redzic JS, Zohar Eisenmesser E. Relaxation and single site multiple mutations to identify and control allosteric networks. Methods. 2023 08; 216:51-57.
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McNaught KJ, Kuatsjah E, Zahn M, Prates ?T, Shao H, Bentley GJ, Pickford AR, Gruber JN, Hestmark KV, Jacobson DA, Poirier BC, Ling C, San Marchi M, Michener WE, Nicora CD, Sanders JN, Szostkiewicz CJ, Velickovic D, Zhou M, Munoz N, Kim YM, Magnuson JK, Burnum-Johnson KE, Houk KN, McGeehan JE, Johnson CW, Beckham GT. Initiation of fatty acid biosynthesis in Pseudomonas putida KT2440. Metab Eng. 2023 03; 76:193-203.
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Bassett J, Rimel JK, Basu S, Basnet P, Luo J, Engel KL, Nagel M, Woyciehowsky A, Ebmeier CC, Kaplan CD, Taatjes DJ, Ranish JA. Systematic mutagenesis of TFIIH subunit p52/Tfb2 identifies residues required for XPB/Ssl2 subunit function and genetic interactions with TFB6. J Biol Chem. 2022 10; 298(10):102433.
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Bae T, Fasching L, Wang Y, Shin JH, Suvakov M, Jang Y, Norton S, Dias C, Mariani J, Jourdon A, Wu F, Panda A, Pattni R, Chahine Y, Yeh R, Roberts RC, Huttner A, Kleinman JE, Hyde TM, Straub RE, Walsh CA, Urban AE, Leckman JF, Weinberger DR, Vaccarino FM, Abyzov A. Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability. Science. 2022 07 29; 377(6605):511-517.
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Kirby MB, Whitehead TA. Facile Assembly of Combinatorial Mutagenesis Libraries Using Nicking Mutagenesis. Methods Mol Biol. 2022; 2461:85-109.
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Alam M, Arunagiri A, Haataja L, Torres M, Larkin D, Kappler J, Jin N, Arvan P. Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes. Diabetes. 2021 11; 70(11):2580-2594.
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Seplyarskiy VB, Soldatov RA, Koch E, McGinty RJ, Goldmann JM, Hernandez RD, Barnes K, Correa A, Burchard EG, Ellinor PT, McGarvey ST, Mitchell BD, Vasan RS, Redline S, Silverman E, Weiss ST, Arnett DK, Blangero J, Boerwinkle E, He J, Montgomery C, Rao DC, Rotter JI, Taylor KD, Brody JA, Chen YI, de Las Fuentes L, Hwu CM, Rich SS, Manichaikul AW, Mychaleckyj JC, Palmer ND, Smith JA, Kardia SLR, Peyser PA, Bielak LF, O'Connor TD, Emery LS, Gilissen C, Wong WSW, Kharchenko PV, Sunyaev S. Population sequencing data reveal a compendium of mutational processes in the human germ line. Science. 2021 08 27; 373(6558):1030-1035.
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Yang C, Tian C, Hoffman TE, Jacobsen NK, Spencer SL. Melanoma subpopulations that rapidly escape MAPK pathway inhibition incur DNA damage and rely on stress signalling. Nat Commun. 2021 03 19; 12(1):1747.
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