High-Temperature Requirement A Serine Peptidase 1
"High-Temperature Requirement A Serine Peptidase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A secreted serine protease that contains a Kazal domain-like region and a C-terminal PDZ domain. It has a broad range of targets that include EXTRACELLULAR MATRIX PROTEINS; PROTEOGLYCANS; and INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS. Mutations in the HTRA1 gene are associated with AGE-RELATED MACULAR DEGENERATION 7 and Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CARASIL).
| Descriptor ID |
D000074289
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| MeSH Number(s) |
D08.811.277.656.300.760.420 D08.811.277.656.959.350.420
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "High-Temperature Requirement A Serine Peptidase 1".
Below are MeSH descriptors whose meaning is more specific than "High-Temperature Requirement A Serine Peptidase 1".
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Below are the most recent publications written about "High-Temperature Requirement A Serine Peptidase 1" by people in Profiles.
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Maguire MG, Daniel E, Shah AR, Grunwald JE, Hagstrom SA, Avery RL, Huang J, Martin RW, Roth DB, Castellarin AA, Bakri SJ, Fine SL, Martin DF. Incidence of choroidal neovascularization in the fellow eye in the comparison of age-related macular degeneration treatments trials. Ophthalmology. 2013 Oct; 120(10):2035-41.