 DNA Helicases
"DNA Helicases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing transient opening. In addition DNA helicases are DNA-dependent ATPases that harness the free energy of ATP hydrolysis to translocate DNA strands.
| Descriptor ID |
D004265
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| MeSH Number(s) |
D08.811.277.040.025.159 D08.811.399.340
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| Concept/Terms |
DNA Helicases- DNA Helicases
- Helicases, DNA
- DNA Unwinding Proteins
- Unwinding Proteins, DNA
ATP-Dependent DNA Helicases- ATP-Dependent DNA Helicases
- ATP Dependent DNA Helicases
- DNA Helicases, ATP-Dependent
- Helicases, ATP-Dependent DNA
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Below are MeSH descriptors whose meaning is more general than "DNA Helicases".
Below are MeSH descriptors whose meaning is more specific than "DNA Helicases".
This graph shows the total number of publications written about "DNA Helicases" by people in this website by year, and whether "DNA Helicases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 1 | 1 | 2 | | 1998 | 1 | 0 | 1 | | 1999 | 2 | 1 | 3 | | 2000 | 5 | 0 | 5 | | 2002 | 0 | 1 | 1 | | 2003 | 2 | 0 | 2 | | 2004 | 4 | 1 | 5 | | 2005 | 4 | 1 | 5 | | 2007 | 1 | 0 | 1 | | 2008 | 2 | 0 | 2 | | 2009 | 5 | 1 | 6 | | 2010 | 4 | 1 | 5 | | 2011 | 5 | 0 | 5 | | 2012 | 4 | 0 | 4 | | 2013 | 2 | 1 | 3 | | 2014 | 0 | 1 | 1 | | 2015 | 4 | 2 | 6 | | 2016 | 1 | 2 | 3 | | 2017 | 3 | 0 | 3 | | 2018 | 2 | 2 | 4 | | 2019 | 1 | 4 | 5 | | 2020 | 3 | 0 | 3 | | 2021 | 2 | 1 | 3 | | 2022 | 2 | 1 | 3 | | 2023 | 1 | 1 | 2 |
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Below are the most recent publications written about "DNA Helicases" by people in Profiles.
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Jolly AJ, Lu S, Dubner AM, Strand KA, Mutryn MF, Pilotti-Riley A, Danis EP, Nemenoff RA, Moulton KS, Majesky MW, Weiser-Evans MC. Redistribution of the chromatin remodeler Brg1 directs smooth muscle-derived adventitial progenitor-to-myofibroblast differentiation and vascular fibrosis. JCI Insight. 2023 05 08; 8(9).
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Liu J, Chaves-Arquero B, Wei P, Tencer AH, Ruiz-Albor A, Zhang G, Blanco FJ, Kutateladze TG. Molecular insight into the PCNA-binding mode of FBH1. Structure. 2023 May 04; 31(5):511-517.e3.
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Bassett J, Rimel JK, Basu S, Basnet P, Luo J, Engel KL, Nagel M, Woyciehowsky A, Ebmeier CC, Kaplan CD, Taatjes DJ, Ranish JA. Systematic mutagenesis of TFIIH subunit p52/Tfb2 identifies residues required for XPB/Ssl2 subunit function and genetic interactions with TFB6. J Biol Chem. 2022 10; 298(10):102433.
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Prigaro BJ, Esquer H, Zhou Q, Pike LA, Awolade P, Lai XH, Abraham AD, Abbott JM, Matter B, Kompella UB, Messersmith WA, Gustafson DL, LaBarbera DV. Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L. J Med Chem. 2022 03 10; 65(5):3943-3961.
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Taylor AMK, Okoniewski SR, Uyetake L, Perkins TT. Force-Activated DNA Substrates for In Situ Generation of ssDNA and Designed ssDNA/dsDNA Structures in an Optical-Trapping Assay. Methods Mol Biol. 2022; 2478:273-312.
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Hagman JR, Arends T, Laborda C, Knapp JR, Harmacek L, O'Connor BP. Chromodomain helicase DNA-binding 4 (CHD4) regulates early B cell identity and V(D)J recombination. Immunol Rev. 2022 01; 305(1):29-42.
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Jillson LK, Rider LC, Rodrigues LU, Romero L, Karimpour-Fard A, Nieto C, Gillette C, Torkko K, Danis E, Smith EE, Nolley R, Peehl DM, Lucia MS, Costello JC, Cramer SD. MAP3K7 Loss Drives Enhanced Androgen Signaling and Independently Confers Risk of Recurrence in Prostate Cancer with Joint Loss of CHD1. Mol Cancer Res. 2021 07; 19(7):1123-1136.
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Tomko EJ, Luyties O, Rimel JK, Tsai CL, Fuss JO, Fishburn J, Hahn S, Tsutakawa SE, Taatjes DJ, Galburt EA. The Role of XPB/Ssl2 dsDNA Translocase Processivity in Transcription Start-site Scanning. J Mol Biol. 2021 07 09; 433(14):166813.
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Matheny T, Van Treeck B, Huynh TN, Parker R. RNA partitioning into stress granules is based on the summation of multiple interactions. RNA. 2021 02; 27(2):174-189.
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Abbott JM, Zhou Q, Esquer H, Pike L, Broneske TP, Rinaldetti S, Abraham AD, Ramirez DA, Lunghofer PJ, Pitts TM, Regan DP, Tan AC, Gustafson DL, Messersmith WA, LaBarbera DV. First-in-Class Inhibitors of Oncogenic CHD1L with Preclinical Activity against Colorectal Cancer. Mol Cancer Ther. 2020 08; 19(8):1598-1612.
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