DNA Topoisomerases
"DNA Topoisomerases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that regulate the topology of DNA by actions such as breaking, relaxing, passing, and rejoining strands of DNA in cells. These enzymes are important components of the DNA replication system. They are classified by their substrate specificities. DNA TOPOISOMERASE I enzymes act on a single strand of DNA. DNA TOPOISOMERASE II enzymes act on double strands of DNA.
| Descriptor ID |
D026942
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| MeSH Number(s) |
D08.811.399.403
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| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "DNA Topoisomerases".
Below are MeSH descriptors whose meaning is more specific than "DNA Topoisomerases".
This graph shows the total number of publications written about "DNA Topoisomerases" by people in this website by year, and whether "DNA Topoisomerases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Topoisomerases" by people in Profiles.
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Shewach DS, Kuchta RD. Introduction to cancer chemotherapeutics. Chem Rev. 2009 Jul; 109(7):2859-61.