 Pancreatic Polypeptide
"Pancreatic Polypeptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 36-amino acid pancreatic hormone that is secreted mainly by endocrine cells found at the periphery of the ISLETS OF LANGERHANS and adjacent to cells containing SOMATOSTATIN and GLUCAGON. Pancreatic polypeptide (PP), when administered peripherally, can suppress gastric secretion, gastric emptying, pancreatic enzyme secretion, and appetite. A lack of pancreatic polypeptide (PP) has been associated with OBESITY in rats and mice.
| Descriptor ID |
D010191
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| MeSH Number(s) |
D06.472.699.587.700 D12.644.400.600 D12.644.548.586.700 D12.776.631.650.600
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pancreatic Polypeptide".
Below are MeSH descriptors whose meaning is more specific than "Pancreatic Polypeptide".
This graph shows the total number of publications written about "Pancreatic Polypeptide" by people in this website by year, and whether "Pancreatic Polypeptide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pancreatic Polypeptide" by people in Profiles.
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Guy DA, Sandoval D, Richardson MA, Tate D, Flakoll PJ, Davis SN. Differing physiological effects of epinephrine in type 1 diabetes and nondiabetic humans. Am J Physiol Endocrinol Metab. 2005 Jan; 288(1):E178-86.
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Sussel L, Kalamaras J, Hartigan-O'Connor DJ, Meneses JJ, Pedersen RA, Rubenstein JL, German MS. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. Development. 1998 Jun; 125(12):2213-21.
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Walczak M, Mrozikiewicz D, Dmochowski K, Rewers M, Cichy W. Serum pancreatic polypeptide and glucagon immunoreactivity in fasting healthy and diabetic children. Mater Med Pol. 1989 Jan-Mar; 21(1):38-42.
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Altiere RJ, Diamond L. Comparison of vasoactive intestinal peptide and isoproterenol relaxant effects in isolated cat airways. J Appl Physiol Respir Environ Exerc Physiol. 1984 Apr; 56(4):986-92.
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