 Pituitary Adenylate Cyclase-Activating Polypeptide
"Pituitary Adenylate Cyclase-Activating Polypeptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multi-function neuropeptide that acts throughout the body by elevating intracellular cyclic AMP level via its interaction with PACAP RECEPTORS. Although first isolated from hypothalamic extracts and named for its action on the pituitary, it is widely distributed in the central and peripheral nervous systems. PACAP is important in the control of endocrine and homeostatic processes, such as secretion of pituitary and gut hormones and food intake.
| Descriptor ID |
D051219
|
| MeSH Number(s) |
D12.644.276.860.887 D12.644.400.625 D12.776.467.860.887 D12.776.631.600.887 D12.776.631.650.625 D23.529.850.887
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Pituitary Adenylate Cyclase-Activating Polypeptide".
Below are MeSH descriptors whose meaning is more specific than "Pituitary Adenylate Cyclase-Activating Polypeptide".
This graph shows the total number of publications written about "Pituitary Adenylate Cyclase-Activating Polypeptide" by people in this website by year, and whether "Pituitary Adenylate Cyclase-Activating Polypeptide" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 1 | 2 | | 2017 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Pituitary Adenylate Cyclase-Activating Polypeptide" by people in Profiles.
-
Waschek JA, Baca SM, Akerman S. PACAP and migraine headache: immunomodulation of neural circuits in autonomic ganglia and brain parenchyma. J Headache Pain. 2018 Mar 13; 19(1):23.
-
Contina A, Bridge ES, Ross JD, Shipley JR, Kelly JF. Examination of Clock and Adcyap1 gene variation in a neotropical migratory passerine. PLoS One. 2018; 13(1):e0190859.
-
Hoffmann J, Baca SM, Akerman S. Neurovascular mechanisms of migraine and cluster headache. J Cereb Blood Flow Metab. 2019 04; 39(4):573-594.
-
Woods IG, Schoppik D, Shi VJ, Zimmerman S, Coleman HA, Greenwood J, Soucy ER, Schier AF. Neuropeptidergic signaling partitions arousal behaviors in zebrafish. J Neurosci. 2014 Feb 26; 34(9):3142-60.
-
D'Alessandro A, Cervia D, Catalani E, Gevi F, Zolla L, Casini G. Protective effects of the neuropeptides PACAP, substance P and the somatostatin analogue octreotide in retinal ischemia: a metabolomic analysis. Mol Biosyst. 2014 Jun; 10(6):1290-304.
-
Chowdhury D, Marco S, Brooks IM, Zandueta A, Rao Y, Haucke V, Wesseling JF, Tavalin SJ, P?rez-Ota?o I. Tyrosine phosphorylation regulates the endocytosis and surface expression of GluN3A-containing NMDA receptors. J Neurosci. 2013 Feb 27; 33(9):4151-64.
-
Bhave SV, Hoffman PL. Phosphatidylinositol 3'-OH kinase and protein kinase A pathways mediate the anti-apoptotic effect of pituitary adenylyl cyclase-activating polypeptide in cultured cerebellar granule neurons: modulation by ethanol. J Neurochem. 2004 Jan; 88(2):359-69.
-
Schmidt-Choudhury A, Furuta GT, Galli SJ, Schmidt WE, Wershil BK. Mast cells contribute to PACAP-induced dermal oedema in mice. Regul Pept. 1999 Jun 30; 82(1-3):65-9.
-
Matsumoto H, Koyama C, Sawada T, Koike K, Hirota K, Miyake A, Arimura A, Inoue K. Pituitary folliculo-stellate-like cell line (TtT/GF) responds to novel hypophysiotropic peptide (pituitary adenylate cyclase-activating peptide), showing increased adenosine 3',5'-monophosphate and interleukin-6 secretion and cell proliferation. Endocrinology. 1993 Nov; 133(5):2150-5.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|