 Neurotensin
"Neurotensin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biologically active tridecapeptide isolated from the hypothalamus. It has been shown to induce hypotension in the rat, to stimulate contraction of guinea pig ileum and rat uterus, and to cause relaxation of rat duodenum. There is also evidence that it acts as both a peripheral and a central nervous system neurotransmitter.
| Descriptor ID |
D009496
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| MeSH Number(s) |
D12.644.400.550 D12.776.631.650.550
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Neurotensin".
Below are MeSH descriptors whose meaning is more specific than "Neurotensin".
This graph shows the total number of publications written about "Neurotensin" by people in this website by year, and whether "Neurotensin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 2 | 0 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neurotensin" by people in Profiles.
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Piccart E, Courtney NA, Branch SY, Ford CP, Beckstead MJ. Neurotensin Induces Presynaptic Depression of D2 Dopamine Autoreceptor-Mediated Neurotransmission in Midbrain Dopaminergic Neurons. J Neurosci. 2015 Aug 05; 35(31):11144-52.
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Wu Z, Li L, Liu S, Yakushijin F, Yakushijin K, Horne D, Conti PS, Li Z, Kandeel F, Shively JE. Facile Preparation of a Thiol-Reactive (18)F-Labeling Agent and Synthesis of (18)F-DEG-VS-NT for PET Imaging of a Neurotensin Receptor-Positive Tumor. J Nucl Med. 2014 Jul; 55(7):1178-84.
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Root DH, Ma S, Barker DJ, Megehee L, Striano BM, Ralston CM, Fabbricatore AT, West MO. Differential roles of ventral pallidum subregions during cocaine self-administration behaviors. J Comp Neurol. 2013 Feb 15; 521(3):558-88.
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Dungan Lemko HM, Naderi R, Adjan V, Jennes LH, Navarro VM, Clifton DK, Steiner RA. Interactions between neurotensin and GnRH neurons in the positive feedback control of GnRH/LH secretion in the mouse. Am J Physiol Endocrinol Metab. 2010 Jan; 298(1):E80-8.
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Drevon GF, Urbanke C, Russell AJ. Enzyme-containing Michael-adduct-based coatings. Biomacromolecules. 2003 May-Jun; 4(3):675-82.
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Day HE, Vittoz NM, Oates MM, Badiani A, Watson SJ, Robinson TE, Akil H. A 6-hydroxydopamine lesion of the mesostriatal dopamine system decreases the expression of corticotropin releasing hormone and neurotensin mRNAs in the amygdala and bed nucleus of the stria terminalis. Brain Res. 2002 Aug 02; 945(2):151-9.
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Erwin VG, Radcliffe R, Deitrich RA. Neurotensin levels in specific brain regions and hypnotic sensitivity to ethanol and pentobarbital as a function of time after haloperidol administration in selectively bred rat lines. J Pharmacol Exp Ther. 2001 Nov; 299(2):698-704.
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Helmreich DL, Watkins LR, Deak T, Maier SF, Akil H, Watson SJ. The effect of stressor controllability on stress-induced neuropeptide mRNA expression within the paraventricular nucleus of the hypothalamus. J Neuroendocrinol. 1999 Feb; 11(2):121-8.
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Cathala L, Paupardin-Tritsch D. Neurotensin inhibition of the hyperpolarization-activated cation current (Ih) in the rat substantia nigra pars compacta implicates the protein kinase C pathway. J Physiol. 1997 Aug 15; 503 ( Pt 1):87-97.
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Erwin VG, Radcliffe RA, Gehle VM, Jones BC. Common quantitative trait loci for alcohol-related behaviors and central nervous system neurotensin measures: locomotor activation. J Pharmacol Exp Ther. 1997 Feb; 280(2):919-26.
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