 Orexins
"Orexins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Neuropeptide hormones that play a role in regulating a variety of behavioral and physiological processes in response to motivational stimuli.
| Descriptor ID |
D000068797
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| MeSH Number(s) |
D12.644.400.360 D12.776.631.650.363
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| Concept/Terms |
Orexin-B- Orexin-B
- Orexin B
- Hypocretin-2
- Hypocretin 2
Orexin-A- Orexin-A
- Orexin A
- Hypocretin-1
- Hypocretin 1
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Below are MeSH descriptors whose meaning is more general than "Orexins".
Below are MeSH descriptors whose meaning is more specific than "Orexins".
This graph shows the total number of publications written about "Orexins" by people in this website by year, and whether "Orexins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Orexins" by people in Profiles.
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Neylan TC, Richards A, Metzler TJ, Ruoff LM, Varbel J, O'Donovan A, Sivasubramanian M, Motraghi T, Hlavin J, Batki SL, Inslicht SS, Samuelson K, Morairty SR, Kilduff TS. Acute cognitive effects of the hypocretin receptor antagonist almorexant relative to zolpidem and placebo: a randomized clinical trial. Sleep. 2020 10 13; 43(10).
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Thomasy HE, Opp MR. Hypocretin Mediates Sleep and Wake Disturbances in a Mouse Model of Traumatic Brain Injury. J Neurotrauma. 2019 03 01; 36(5):802-814.
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Amin R, Simakajornboon N, Szczesniak R, Inge T. Early improvement in obstructive sleep apnea and increase in orexin levels after bariatric surgery in adolescents and young adults. Surg Obes Relat Dis. 2017 Jan; 13(1):95-100.
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Rorabaugh JM, Stratford JM, Zahniser NR. A relationship between reduced nucleus accumbens shell and enhanced lateral hypothalamic orexin neuronal activation in long-term fructose bingeing behavior. PLoS One. 2014; 9(4):e95019.
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Johnson PL, Samuels BC, Fitz SD, Lightman SL, Lowry CA, Shekhar A. Activation of the orexin 1 receptor is a critical component of CO2-mediated anxiety and hypertension but not bradycardia. Neuropsychopharmacology. 2012 Jul; 37(8):1911-22.
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Pankevich DE, Teegarden SL, Hedin AD, Jensen CL, Bale TL. Caloric restriction experience reprograms stress and orexigenic pathways and promotes binge eating. J Neurosci. 2010 Dec 01; 30(48):16399-407.
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Espa?a RA, Oleson EB, Locke JL, Brookshire BR, Roberts DC, Jones SR. The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine system. Eur J Neurosci. 2010 Jan; 31(2):336-48.
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Teegarden SL, Nestler EJ, Bale TL. Delta FosB-mediated alterations in dopamine signaling are normalized by a palatable high-fat diet. Biol Psychiatry. 2008 Dec 01; 64(11):941-50.
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Huesa G, van den Pol AN, Finger TE. Differential distribution of hypocretin (orexin) and melanin-concentrating hormone in the goldfish brain. J Comp Neurol. 2005 Aug 08; 488(4):476-91.
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Dauvilliers Y, Carlander B, Molinari N, Desautels A, Okun M, Tafti M, Montplaisir J, Mignot E, Billiard M. Month of birth as a risk factor for narcolepsy. Sleep. 2003 Sep; 26(6):663-5.
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