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Search Results to Thomas R Cech

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Cech, Thomas

One or more keywords matched the following items that are connected to Cech, Thomas

Item Type	Name
Academic Article	Organization of highly repeated sequences in mouse main-band DNA.
Academic Article	Self-splicing RNA: implications for evolution.
Academic Article	Characterization of the rapidly renaturing sequences in the main CsCl density bands of Drosophila, mouse, and human DNA.
Academic Article	Characterization of the most rapidly renaturing sequences in mouse main-band DNA.
Academic Article	Electron microscopy of DNA cross-linked with trimethylpsoralen: a probe for chromatin structure.
Academic Article	Alkaline gel electrophoresis of deoxyribonucleic acid photoreacted with trimethylpsoralen: rapid and sensitive detection of interstrand cross-links.
Academic Article	Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena.
Academic Article	Transcribed and non-transcribed regions of Tetrahymena ribosomal gene chromatin have different accessibilities to micrococcal nuclease.
Academic Article	Different nucleosome spacing in transcribed and non-transcribed regions of the ribosomal RNA gene in Tetrahymena thermophila.
Academic Article	Fate of an intervening sequence ribonucleic acid: excision and cyclization of the Tetrahymena ribosomal ribonucleic acid intervening sequence in vivo.
Academic Article	The intervening sequence excised from the ribosomal RNA precursor of Tetrahymena contains a 5-terminal guanosine residue not encoded by the DNA.
Academic Article	An electron microscopic study of mouse foldback DNA.
Academic Article	Chromatin structure of the ribosomal RNA genes of Tetrahymena thermophila as analyzed by trimethylpsoralen crosslinking in vivo.
Academic Article	Tertiary interactions with the internal guide sequence mediate docking of the P1 helix into the catalytic core of the Tetrahymena ribozyme.
Academic Article	Telomerase RNA localized in the replication band and spherical subnuclear organelles in hypotrichous ciliates.
Academic Article	Movement of the guide sequence during RNA catalysis by a group I ribozyme.
Academic Article	The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction.
Academic Article	Photocrosslinking of 5-iodouracil-substituted RNA and DNA to proteins.
Academic Article	Telomerase RNAs of different ciliates have a common secondary structure and a permuted template.
Academic Article	Telomeric protein-DNA point contacts identified by photo-cross-linking using 5-bromodeoxyuridine.
Academic Article	Oxytricha telomere-binding protein: separable DNA-binding and dimerization domains of the alpha-subunit.
Academic Article	The beta subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA.
Academic Article	Secondary structure of the Tetrahymena ribosomal RNA intervening sequence: structural homology with fungal mitochondrial intervening sequences.
Academic Article	Mitochondrial import of only one of three nuclear-encoded glutamine tRNAs in Tetrahymena thermophila.
Academic Article	Regulation of telomere length and function by a Myb-domain protein in fission yeast.
Academic Article	Mutagenesis and comparative sequence analysis of a base triple joining the two domains of group I ribozymes.
Academic Article	Euplotes telomerase: evidence for limited base-pairing during primer elongation and dGTP as an effector of translocation.
Academic Article	Identification of ribozymes within a ribozyme library that efficiently cleave a long substrate RNA.
Academic Article	Peptide bond formation by in vitro selected ribozymes.
Academic Article	Reversing time: origin of telomerase.
Academic Article	Telomerase and chromosome end maintenance.
Academic Article	Chromosome end games.
Academic Article	Characterization of a G-quartet formation reaction promoted by the beta-subunit of the Oxytricha telomere-binding protein.
Academic Article	Oxytricha telomere-binding protein: DNA-dependent dimerization of the alpha and beta subunits.
Academic Article	Purification of telomerase from Euplotes aediculatus: requirement of a primer 3' overhang.
Academic Article	Kinetic and secondary structure analysis of Naegleria andersoni GIR1, a group I ribozyme whose putative biological function is site-specific hydrolysis.
Academic Article	Telomerase and the chromosome end replication problem.
Academic Article	The intervening sequence RNA of Tetrahymena is an enzyme.
Academic Article	Modulation of telomerase activity by telomere DNA-binding proteins in Oxytricha.
Academic Article	Cloning and expression of genes for the Oxytricha telomere-binding protein: specific subunit interactions in the telomeric complex.
Academic Article	The Euplotes La motif protein p43 has properties of a telomerase-specific subunit.
Academic Article	Tetrahymena telomerase is active as a monomer.
Academic Article	A template-proximal RNA paired element contributes to Saccharomyces cerevisiae telomerase activity.
Academic Article	Chromatin structure in living cells.
Academic Article	Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection.
Academic Article	Expression of a RecQ helicase homolog affects progression through crisis in fission yeast lacking telomerase.
Academic Article	Soluble domains of telomerase reverse transcriptase identified by high-throughput screening.
Academic Article	Switching human telomerase on and off with hPOT1 protein in vitro.
Academic Article	Atomic level architecture of group I introns revealed.
Academic Article	POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates.
Academic Article	Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase.
Academic Article	Iron(II)-ethylenediaminetetraacetic acid catalyzed cleavage of RNA and DNA oligonucleotides: similar reactivity toward single- and double-stranded forms.
Academic Article	Mutation in TERT separates processivity from anchor-site function.
Academic Article	Effect of monovalent cation-induced telomeric DNA structure on the binding of Oxytricha telomeric protein.
Academic Article	A model for the RNA-catalyzed replication of RNA.
Academic Article	The chemistry of self-splicing RNA and RNA enzymes.
Academic Article	How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.
Academic Article	Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants.
Academic Article	An electron microscopic study of the photochemical cross-linking of DNA in guinea pig epidermis by psoralen derivatives.
Academic Article	Assembly and self-association of oxytricha telomeric nucleoprotein complexes.
Academic Article	Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase.
Academic Article	Monovalent cation-induced structure of telomeric DNA: the G-quartet model.
Academic Article	Multiple POT1-TPP1 proteins coat and compact long telomeric single-stranded DNA.
Academic Article	Pot1, the putative telomere end-binding protein in fission yeast and humans.
Academic Article	Two versions of the gene encoding the 41-kilodalton subunit of the telomere binding protein of Oxytricha nova.
Academic Article	DNA cleavage catalysed by the ribozyme from Tetrahymena.
Academic Article	The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis.
Academic Article	Mutually exclusive binding of telomerase RNA and DNA by Ku alters telomerase recruitment model.
Academic Article	The telomeres of the linear mitochondrial DNA of Tetrahymena thermophila consist of 53 bp tandem repeats.
Academic Article	DNA-protein interactions in the Drosophila virilis mitochondrial chromosome.
Academic Article	Chromatin structure at the replication origins and transcription-initiation regions of the ribosomal RNA genes of Tetrahymena.
Academic Article	Chromatin structure of the molecular ends of Oxytricha macronuclear DNA: phased nucleosomes and a telomeric complex.
Academic Article	Electron microscopy of DNA crosslinked with trimethylpsoralen: test of the secondary structure of eukaryotic inverted repeat sequences.
Academic Article	Replication of the extrachromosomal ribosomal RNA genes of Tetrahymena thermophilia.
Academic Article	In vitro splicing of the ribosomal RNA precursor in nuclei of Tetrahymena.
Academic Article	Telomerase and DNA end replication: no longer a lagging strand problem?
Academic Article	Phosphorylation of the Oxytricha telomere protein: possible cell cycle regulation.
Academic Article	Contributions of 2'-hydroxyl groups of the RNA substrate to binding and catalysis by the Tetrahymena ribozyme. An energetic picture of an active site composed of RNA.
Academic Article	DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA.
Academic Article	Ribozyme-mediated repair of defective mRNA by targeted, trans-splicing.
Academic Article	Beginning to understand the end of the chromosome.
Academic Article	Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n.
Academic Article	Method for determining RNA 3' ends and application to human telomerase RNA.
Academic Article	The anchor site of telomerase from Euplotes aediculatus revealed by photo-cross-linking to single- and double-stranded DNA primers.
Academic Article	Reverse transcriptase motifs in the catalytic subunit of telomerase.
Academic Article	Molecular cloning of telomere-binding protein genes from Stylonychia mytilis.
Academic Article	Telomerase catalytic subunit homologs from fission yeast and human.
Academic Article	Telomerase is a true reverse transcriptase. A review.
Academic Article	Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax.
Academic Article	Two modes of survival of fission yeast without telomerase.
Academic Article	Inhibition of telomerase by G-quartet DNA structures.
Academic Article	Protection of telomeres by the Ku protein in fission yeast.
Academic Article	The POT1-TPP1 telomere complex is a telomerase processivity factor.
Academic Article	Effects of nucleotide analogues on Euplotes aediculatus telomerase processivity: evidence for product-assisted translocation.
Academic Article	Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction.
Academic Article	N-terminal domain of yeast telomerase reverse transcriptase: recruitment of Est3p to the telomerase complex.
Academic Article	Sequence-specific and 3'-end selective single-strand DNA binding by the Oxytricha nova telomere end binding protein alpha subunit.
Academic Article	Global expression changes resulting from loss of telomeric DNA in fission yeast.
Academic Article	Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro.
Academic Article	The generality of self-splicing RNA: relationship to nuclear mRNA splicing.
Academic Article	Oxytricha telomeric nucleoprotein complexes reconstituted with synthetic DNA.
Academic Article	Secondary structure of the circular form of the Tetrahymena rRNA intervening sequence: a technique for RNA structure analysis using chemical probes and reverse transcriptase.
Academic Article	POT1-TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation.
Academic Article	Ku can contribute to telomere lengthening in yeast at multiple positions in the telomerase RNP.
Academic Article	DNA-induced dimerization of the single-stranded DNA binding telomeric protein Pot1 from Schizosaccharomyces pombe.
Academic Article	Properties of the telomeric DNA-binding protein from Oxytricha nova.
Academic Article	Phylogenetic relationships and altered genome structures among Tetrahymena mitochondrial DNAs.
Academic Article	RNA recognition by the DNA end-binding Ku heterodimer.
Academic Article	Cross-linking of DNA with trimethylpsoralen is a probe for chromatin structure.
Academic Article	G-strings at chromosome ends.
Academic Article	Deletion of nonconserved helices near the 3' end of the rRNA intron of Tetrahymena thermophila alters self-splicing but not core catalytic activity.
Academic Article	Coupling of Tetrahymena ribosomal RNA splicing to beta-galactosidase expression in Escherichia coli.
Academic Article	Telomeric DNA-protein interactions of Oxytricha macronuclear DNA.
Academic Article	Mitochondrial telomeres: surprising diversity of repeated telomeric DNA sequences among six species of Tetrahymena.
Academic Article	Telomeric repeats of Tetrahymena malaccensis mitochondrial DNA: a multimodal distribution that fluctuates erratically during growth.
Concept	DNA, Viral
Concept	DNA, Bacterial
Concept	DNA, Ribosomal
Concept	DNA Methylation
Concept	Sequence Analysis, DNA
Concept	DNA-Binding Proteins
Concept	DNA Helicases
Concept	RNA-Directed DNA Polymerase
Concept	DNA, Complementary
Concept	DNA Footprinting
Concept	DNA Damage
Concept	DNA, Protozoan
Concept	DNA-Directed DNA Polymerase
Concept	DNA Probes
Concept	DNA Modification Methylases
Concept	DNA Ligases
Concept	DNA
Concept	DNA, Mitochondrial
Concept	DNA Nucleotidylexotransferase
Concept	DNA Replication
Concept	DNA Restriction Enzymes
Concept	DNA (Cytosine-5-)-Methyltransferases
Concept	DNA, Fungal
Concept	DNA Primers
Concept	DNA-Directed RNA Polymerases
Concept	DNA Polymerase I
Concept	DNA Repair
Concept	DNA, Single-Stranded
Concept	DNA Transposable Elements
Concept	DNA Mutational Analysis
Concept	DNA Primase
Academic Article	DNA-protein interactions in the Drosophila melanogaster mitochondrial genome as deduced from trimethylpsoralen crosslinking patterns.
Academic Article	RNA seeds higher-order assembly of FUS protein.
Academic Article	Telomerase in bladder cancer: back to a better future?
Academic Article	Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance.
Academic Article	Contributions of the TEL-patch amino acid cluster on TPP1 to telomeric DNA synthesis by human telomerase.
Academic Article	Biochemical Properties and Biological Functions of FET Proteins.
Academic Article	Nucleic acid-binding specificity of human FUS protein.
Academic Article	A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression.
Grant	Telomerase and Telomeres: Structure, Function and Regulation
Grant	CHROMATIN STRUCTURE OF A TRANSCRIPTION UNIT
Academic Article	How do lncRNAs regulate transcription?
Academic Article	Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA.
Academic Article	Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes.
Academic Article	Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2.
Academic Article	Fission yeast telosomes: non-canonical histone-containing chromatin structures dependent on shelterin and RNA.
Concept	DNA (Cytosine-5-)-Methyltransferase 1
Concept	DNA Ligase ATP
Concept	DNA End-Joining Repair
Academic Article	Bending and looping of long DNA by Polycomb repressive complex 2 revealed by AFM imaging in liquid.
Academic Article	Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes.
Academic Article	The structure of human CST reveals a decameric assembly bound to telomeric DNA.
Academic Article	Allele-specific proximal promoter hypomethylation of the telomerase reverse transcriptase gene (TERT) associates with TERT expression in multiple cancers.
Academic Article	Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization.
Academic Article	CST does not evict elongating telomerase but prevents initiation by ssDNA binding.
Academic Article	Reconstitution of a telomeric replicon organized by CST.
Academic Article	DNMT1 inhibition by pUG-fold quadruplex RNA.
Academic Article	Multiple RNA- and DNA-binding proteins exhibit direct transfer of polynucleotides with implications for target-site search.
Academic Article	PRC2 direct transfer from G-quadruplex RNA to dsDNA has implications for RNA-binding chromatin modifiers.

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