 DNA Probes
"DNA Probes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.
| Descriptor ID |
D015342
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| MeSH Number(s) |
D13.444.600.223 D27.505.259.750.600.223 D27.720.470.530.600.223
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| Concept/Terms |
DNA Probes- DNA Probes
- Probes, DNA
- DNA Hybridization Probes
- Hybridization Probes, DNA
- Probes, DNA Hybridization
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Below are MeSH descriptors whose meaning is more general than "DNA Probes".
Below are MeSH descriptors whose meaning is more specific than "DNA Probes".
This graph shows the total number of publications written about "DNA Probes" by people in this website by year, and whether "DNA Probes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 3 | 3 | | 1995 | 0 | 1 | 1 | | 1996 | 1 | 1 | 2 | | 1997 | 0 | 2 | 2 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 2 | 2 | | 2006 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2010 | 1 | 1 | 2 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Probes" by people in Profiles.
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Traeger JC, Schwartz DK. Interplay of electrostatic repulsion and surface grafting density on surface-mediated DNA hybridization. J Colloid Interface Sci. 2020 Apr 15; 566:369-374.
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Chafin TK, Douglas MR, Douglas ME. MrBait: universal identification and design of targeted-enrichment capture probes. Bioinformatics. 2018 12 15; 34(24):4293-4296.
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MacConaghy KI, Chadly DM, Stoykovich MP, Kaar JL. Label-free detection of missense mutations and methylation differences in the p53 gene using optically diffracting hydrogels. Analyst. 2015 Sep 21; 140(18):6354-62.
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Abel GR, Josephs EA, Luong N, Ye T. A switchable surface enables visualization of single DNA hybridization events with atomic force microscopy. J Am Chem Soc. 2013 May 01; 135(17):6399-402.
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Sinkus ML, Adams CE, Logel J, Freedman R, Leonard S. Expression of immune genes on chromosome 6p21.3-22.1 in schizophrenia. Brain Behav Immun. 2013 Aug; 32:51-62.
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Pedersen BS, Schwartz DA, Yang IV, Kechris KJ. Comb-p: software for combining, analyzing, grouping and correcting spatially correlated P-values. Bioinformatics. 2012 Nov 15; 28(22):2986-8.
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Wenzlau JM, Frisch LM, Hutton JC, Davidson HW. Mapping of conformational autoantibody epitopes in ZNT8. Diabetes Metab Res Rev. 2011 Nov; 27(8):883-6.
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Ryan GJ, Hoff DR, Driver ER, Voskuil MI, Gonzalez-Juarrero M, Basaraba RJ, Crick DC, Spencer JS, Lenaerts AJ. Multiple M. tuberculosis phenotypes in mouse and guinea pig lung tissue revealed by a dual-staining approach. PLoS One. 2010 Jun 14; 5(6):e11108.
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Schreiner SM, Shudy DF, Hatch AL, Opdahl A, Whitman LJ, Petrovykh DY. Controlled and efficient hybridization achieved with DNA probes immobilized solely through preferential DNA-substrate interactions. Anal Chem. 2010 Apr 01; 82(7):2803-10.
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Campbell CJ, Mountford CP, Stoquert HC, Buck AH, Dickinson P, Ferapontova E, Terry JG, Beattie JS, Walton AJ, Crain J, Ghazal P, Mount AR. A DNA nanoswitch incorporating the fluorescent base analogue 2-aminopurine detects single nucleotide mismatches in unlabelled targets. Analyst. 2009 Sep; 134(9):1873-9.
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