 Transcription Factor TFIID
"Transcription Factor TFIID" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major sequence-specific DNA-binding component involved in the activation of transcription of RNA POLYMERASE II. It was originally described as a complex of TATA-BOX BINDING PROTEIN and TATA-BINDING PROTEIN ASSOCIATED FACTORS. It is now know that TATA BOX BINDING PROTEIN-LIKE PROTEINS may take the place of TATA-box binding protein in the complex.
| Descriptor ID |
D035362
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| MeSH Number(s) |
D12.776.260.775.875.750 D12.776.930.930.875.750
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transcription Factor TFIID".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor TFIID".
This graph shows the total number of publications written about "Transcription Factor TFIID" by people in this website by year, and whether "Transcription Factor TFIID" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2001 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 2 | 0 | 2 | | 2017 | 1 | 1 | 2 | | 2018 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 | | 2022 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factor TFIID" by people in Profiles.
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Nguyen MC, Wang D, Klein BJ, Chen Y, Kutateladze TG. Differences and similarities in recognition of co-factors by Taf14. Biochim Biophys Acta Gene Regul Mech. 2023 09; 1866(3):194961.
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Klein BJ, Feigerle JT, Zhang J, Ebmeier CC, Fan L, Singh RK, Wang WW, Schmitt LR, Lee T, Hansen KC, Liu WR, Wang YX, Strahl BD, Anthony Weil P, Kutateladze TG. Taf2 mediates DNA binding of Taf14. Nat Commun. 2022 06 08; 13(1):3177.
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Schier AC, Taatjes DJ. Everything at once: cryo-EM yields remarkable insights into human RNA polymerase II transcription. Nat Struct Mol Biol. 2021 07; 28(7):540-543.
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Fant CB, Levandowski CB, Gupta K, Maas ZL, Moir J, Rubin JD, Sawyer A, Esbin MN, Rimel JK, Luyties O, Marr MT, Berger I, Dowell RD, Taatjes DJ. TFIID Enables RNA Polymerase II Promoter-Proximal Pausing. Mol Cell. 2020 05 21; 78(4):785-793.e8.
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Klein BJ, Vann KR, Andrews FH, Wang WW, Zhang J, Zhang Y, Beloglazkina AA, Mi W, Li Y, Li H, Shi X, Kutateladze AG, Strahl BD, Liu WR, Kutateladze TG. Structural insights into the p-p-p stacking mechanism and DNA-binding activity of the YEATS domain. Nat Commun. 2018 11 01; 9(1):4574.
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Taatjes DJ. The Continuing SAGA of TFIID and RNA Polymerase II Transcription. Mol Cell. 2017 Oct 05; 68(1):1-2.
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Warfield L, Ramachandran S, Baptista T, Devys D, Tora L, Hahn S. Transcription of Nearly All Yeast RNA Polymerase II-Transcribed Genes Is Dependent on Transcription Factor TFIID. Mol Cell. 2017 Oct 05; 68(1):118-129.e5.
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Andrews FH, Shinsky SA, Shanle EK, Bridgers JB, Gest A, Tsun IK, Krajewski K, Shi X, Strahl BD, Kutateladze TG. The Taf14 YEATS domain is a reader of histone crotonylation. Nat Chem Biol. 2016 06; 12(6):396-8.
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Andrews FH, Shanle EK, Strahl BD, Kutateladze TG. The essential role of acetyllysine binding by the YEATS domain in transcriptional regulation. Transcription. 2016; 7(1):14-20.
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Shanle EK, Andrews FH, Meriesh H, McDaniel SL, Dronamraju R, DiFiore JV, Jha D, Wozniak GG, Bridgers JB, Kerschner JL, Krajewski K, Mart?n GM, Morrison AJ, Kutateladze TG, Strahl BD. Association of Taf14 with acetylated histone H3 directs gene transcription and the DNA damage response. Genes Dev. 2015 Sep 01; 29(17):1795-800.
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