 Transcription Factor TFIIA
"Transcription Factor TFIIA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An RNA POLYMERASE II specific transcription factor. It may play a role in transcriptional activation of gene expression by interacting with the TATA-BOX BINDING PROTEIN component of TRANSCRIPTION FACTOR TFIID.
| Descriptor ID |
D035561
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| MeSH Number(s) |
D12.776.260.775.875.374 D12.776.930.930.875.374
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transcription Factor TFIIA".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor TFIIA".
This graph shows the total number of publications written about "Transcription Factor TFIIA" by people in this website by year, and whether "Transcription Factor TFIIA" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factor TFIIA" by people in Profiles.
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Yakovchuk P, Gilman B, Goodrich JA, Kugel JF. RNA polymerase II and TAFs undergo a slow isomerization after the polymerase is recruited to promoter-bound TFIID. J Mol Biol. 2010 Mar 19; 397(1):57-68.
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Smallwood A, Black JC, Tanese N, Pradhan S, Carey M. HP1-mediated silencing targets Pol II coactivator complexes. Nat Struct Mol Biol. 2008 Mar; 15(3):318-20.
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Hieb AR, Halsey WA, Betterton MD, Perkins TT, Kugel JF, Goodrich JA. TFIIA changes the conformation of the DNA in TBP/TATA complexes and increases their kinetic stability. J Mol Biol. 2007 Sep 21; 372(3):619-32.
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Ferguson HA, Kugel JF, Goodrich JA. Kinetic and mechanistic analysis of the RNA polymerase II transcrption reaction at the human interleukin-2 promoter. J Mol Biol. 2001 Dec 14; 314(5):993-1006.
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