 TATA-Box Binding Protein
"TATA-Box Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A general transcription factor that plays a major role in the activation of eukaryotic genes transcribed by RNA POLYMERASES. It binds specifically to the TATA BOX promoter element, which lies close to the position of transcription initiation in RNA transcribed by RNA POLYMERASE II. Although considered a principal component of TRANSCRIPTION FACTOR TFIID it also takes part in general transcription factor complexes involved in RNA POLYMERASE I and RNA POLYMERASE III transcription.
| Descriptor ID |
D035181
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| MeSH Number(s) |
D12.776.260.775.374 D12.776.260.775.875.750.500 D12.776.930.930.374 D12.776.930.930.875.750.500
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| Concept/Terms |
TATA-Box Binding Protein- TATA-Box Binding Protein
- TATA Box Binding Protein
- Transcription Factor TBP
- TATA-Box-Binding Protein
- RNA Polymerase II TATA-Binding Protein
- RNA Polymerase II TATA Binding Protein
- TATA-Binding Protein
- TATA Binding Protein
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Below are MeSH descriptors whose meaning is more general than "TATA-Box Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "TATA-Box Binding Protein".
This graph shows the total number of publications written about "TATA-Box Binding Protein" by people in this website by year, and whether "TATA-Box Binding Protein" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2009 | 1 | 1 | 2 | | 2010 | 1 | 1 | 2 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "TATA-Box Binding Protein" by people in Profiles.
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Warfield L, Ramachandran S, Baptista T, Devys D, Tora L, Hahn S. Transcription of Nearly All Yeast RNA Polymerase II-Transcribed Genes Is Dependent on Transcription Factor TFIID. Mol Cell. 2017 Oct 05; 68(1):118-129.e5.
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Uprety B, Sen R, Bhaumik SR. Eaf1p Is Required for Recruitment of NuA4 in Targeting TFIID to the Promoters of the Ribosomal Protein Genes for Transcriptional Initiation In Vivo. Mol Cell Biol. 2015 Sep 01; 35(17):2947-64.
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He Y, Fang J, Taatjes DJ, Nogales E. Structural visualization of key steps in human transcription initiation. Nature. 2013 Mar 28; 495(7442):481-6.
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Blair RH, Goodrich JA, Kugel JF. Using FRET to monitor protein-induced DNA bending: the TBP-TATA complex as a model system. Methods Mol Biol. 2013; 977:203-15.
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Blair RH, Goodrich JA, Kugel JF. Single-molecule fluorescence resonance energy transfer shows uniformity in TATA binding protein-induced DNA bending and heterogeneity in bending kinetics. Biochemistry. 2012 Sep 25; 51(38):7444-55.
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De Carlo S, Lin SC, Taatjes DJ, Hoenger A. Molecular basis of transcription initiation in Archaea. Transcription. 2010 Sep-Oct; 1(2):103-11.
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Reichlen MJ, Murakami KS, Ferry JG. Functional analysis of the three TATA binding protein homologs in Methanosarcina acetivorans. J Bacteriol. 2010 Mar; 192(6):1511-7.
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Yakovchuk P, Goodrich JA, Kugel JF. B2 RNA and Alu RNA repress transcription by disrupting contacts between RNA polymerase II and promoter DNA within assembled complexes. Proc Natl Acad Sci U S A. 2009 Apr 07; 106(14):5569-74.
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Gilman B, Drullinger LF, Kugel JF, Goodrich JA. TATA-binding protein and transcription factor IIB induce transcript slipping during early transcription by RNA polymerase II. J Biol Chem. 2009 Apr 03; 284(14):9093-8.
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Hieb AR, Halsey WA, Betterton MD, Perkins TT, Kugel JF, Goodrich JA. TFIIA changes the conformation of the DNA in TBP/TATA complexes and increases their kinetic stability. J Mol Biol. 2007 Sep 21; 372(3):619-32.
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