Alleles
"Alleles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Variant forms of the same gene, occupying the same locus on homologous CHROMOSOMES, and governing the variants in production of the same gene product.
| Descriptor ID |
D000483
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| MeSH Number(s) |
G05.360.340.024.340.030
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| Concept/Terms |
Alleles- Alleles
- Allele
- Allelomorphs
- Allelomorph
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Below are MeSH descriptors whose meaning is more general than "Alleles".
Below are MeSH descriptors whose meaning is more specific than "Alleles".
This graph shows the total number of publications written about "Alleles" by people in this website by year, and whether "Alleles" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 4 | 4 | | 1996 | 2 | 5 | 7 | | 1997 | 1 | 4 | 5 | | 1998 | 1 | 8 | 9 | | 1999 | 2 | 7 | 9 | | 2000 | 3 | 8 | 11 | | 2001 | 2 | 14 | 16 | | 2002 | 0 | 13 | 13 | | 2003 | 3 | 10 | 13 | | 2004 | 0 | 21 | 21 | | 2005 | 0 | 14 | 14 | | 2006 | 3 | 17 | 20 | | 2007 | 2 | 25 | 27 | | 2008 | 6 | 18 | 24 | | 2009 | 3 | 27 | 30 | | 2010 | 4 | 21 | 25 | | 2011 | 3 | 24 | 27 | | 2012 | 3 | 22 | 25 | | 2013 | 2 | 32 | 34 | | 2014 | 5 | 31 | 36 | | 2015 | 4 | 32 | 36 | | 2016 | 1 | 27 | 28 | | 2017 | 8 | 37 | 45 | | 2018 | 7 | 28 | 35 | | 2019 | 3 | 31 | 34 | | 2020 | 2 | 21 | 23 | | 2021 | 4 | 26 | 30 | | 2022 | 1 | 12 | 13 | | 2023 | 0 | 9 | 9 | | 2024 | 6 | 15 | 21 | | 2025 | 2 | 13 | 15 |
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Below are the most recent publications written about "Alleles" by people in Profiles.
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Daines CL, Polineni D, Tullis E, Costa S, Linnemann RW, Mall MA, McKone EF, Quon BS, Ringshausen FC, Selvadurai H, Taylor-Cousar JL, Withers NJ, Sawicki GS, Lee T, Ahluwalia N, Morlando Geiger J, Jennings M, Tan YV, Waltz D, Ramsey B, Griese M. Long-Term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Adults and Adolescents with Cystic Fibrosis and at Least One F508del Allele: A Phase 3 Open-Label Extension Study. Am J Respir Crit Care Med. 2025 10; 211(10):1901-1914.
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Wainwright C, McColley SA, McNally P, Powers M, Ratjen F, Rayment JH, Retsch-Bogart G, Roesch E, Ramsey B, McKone EF, Tullis E, Mall MA, Taylor-Cousar JL, Waltz D, Ahluwalia N, Chu C, Scirica CV, Davies JC. Long-Term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Children =6 Years with Cystic Fibrosis and at Least One F508del Allele: A 192-Week, Phase 3, Open-Label Extension Study. Am J Respir Crit Care Med. 2025 Oct; 211(10):1915-1925.
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Mumme-Monheit A, Gustafson GE, Hopkins CA, Bailon-Zambrano R, Sucharov J, Lippincott MJ, Way GP, Colborn KL, Nichols JT. A quadratic paradigm describes the relationship between phenotype severity and variation. Nat Commun. 2025 Sep 01; 16(1):8154.
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Ramadan DJ, Kichula KM, Tao S, Porfilio T, Lande A, Fluge Ø, Mella O, Strand EB, Saugstad OD, Norman PJ, Lie BA, Viken MK. Killer cell immunoglobulin-like receptor (KIR) alleles suggested to be associated with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Brain Behav Immun. 2025 Nov; 130:106098.
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Rai M, Okah P, Shefali SA, Fitt AJ, Shen MZ, Molomjamts M, Pepin R, Nemkov T, D'Alessandro A, Tennessen JM. New alleles of D-2-hydroxyglutarate dehydrogenase enable studies of oncometabolite function in Drosophila melanogaster. G3 (Bethesda). 2025 Aug 06; 15(8).
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Antonicka H, Weraarpachai W, Szigety KM, Kopajtich R, Gibson JB, Van Hove JLK, Friederich MW, Lopriore P, Neuhofer C, Van Hove RA, Cole MA, Reisdorph R, Peterson JT, Dempsey KJ, Ganetzky RD, Mancuso M, Prokisch H, Shoubridge EA. Bi-allelic mutations in FASTKD5 are associated with cytochrome c oxidase deficiency and early- to late-onset Leigh syndrome. Am J Hum Genet. 2025 Jul 03; 112(7):1699-1710.
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Taslimi A, Jeibmann A, Goett-Zink L, Kottke T, Tucker CL. Constitutively active Arabidopsis cryptochrome 2 alleles identified using yeast selection and deep mutational scanning. J Biol Chem. 2025 Jun; 301(6):110265.
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Zhang X, Brody JA, Graff M, Highland HM, Chami N, Xu H, Wang Z, Ferrier KR, Chittoor G, Josyula NS, Meyer M, Gupta S, Li X, Li Z, Allison MA, Becker DM, Bielak LF, Bis JC, Boorgula MP, Bowden DW, Broome JG, Buth EJ, Carlson CS, Chang KM, Chavan S, Chiu YF, Chuang LM, Conomos MP, DeMeo DL, Du M, Duggirala R, Eng C, Fohner AE, Freedman BI, Garrett ME, Guo X, Haiman C, Heavner BD, Hidalgo B, Hixson JE, Ho YL, Hobbs BD, Hu D, Hui Q, Hwu CM, Jackson RD, Jain D, Kalyani RR, Kardia SLR, Kelly TN, Lange EM, LeNoir M, Li C, Le Marchand L, McDonald MN, McHugh CP, Morrison AC, Naseri T, O'Connell J, O'Donnell CJ, Palmer ND, Pankow JS, Perry JA, Peters U, Preuss MH, Rao DC, Regan EA, Reupena SM, Roden DM, Rodriguez-Santana J, Sitlani CM, Smith JA, Tiwari HK, Vasan RS, Wang Z, Weeks DE, Wessel J, Wiggins KL, Wilkens LR, Wilson PWF, Yanek LR, Yoneda ZT, Zhao W, Zöllner S, Arnett DK, Ashley-Koch AE, Barnes KC, Blangero J, Boerwinkle E, Burchard EG, Carson AP, Chasman DI, Ida Chen YD, Curran JE, Fornage M, Gordeuk VR, He J, Heckbert SR, Hou L, Irvin MR, Kooperberg C, Minster RL, Mitchell BD, Nouraie M, Psaty BM, Raffield LM, Reiner AP, Rich SS, Rotter JI, Benjamin Shoemaker M, Smith NL, Taylor KD, Telen MJ, Weiss ST, Zhang Y, Heard-Costa N, Sun YV, Lin X, Cupples LA, Lange LA, Liu CT, Loos RJF, North KE, Justice AE. Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele. Nat Commun. 2025 Apr 11; 16(1):3470.
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Chen Y, Shen M, Gu Y, Xu X, Bian L, Yang F, Chen S, Ji L, Liu J, Zhu J, Zhang Z, Fu Q, Cai Y, Chen H, Xu K, Sun M, Zheng X, Shen J, Zhou H, Zhang M, Haskins K, Yu L, Yang T, Shi Y. Pivotal epitopes for islet antigen-specific CD8+ T cell detection improve classification of suspected type 1 diabetes with the HLA-A*0201 allele. Immunol Res. 2025 Mar 26; 73(1):65.
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Guillouet C, Agostini V, Baujat G, Cocciadiferro D, Pippucci T, Lesieur-Sebellin M, Georget M, Schatz U, Fauth C, Louie RJ, Rogers C, Davis JM, Konstantopoulou V, Mayr JA, Bouman A, Wilke M, VanNoy GE, England EM, Park KL, Brown K, Saenz M, Novelli A, Digilio MC, Mastromoro G, Rongioletti MCA, Piacentini G, Kaiyrzhanov R, Guliyeva S, Hasanova L, Shears D, Bhatnagar I, Stals K, Klaas O, Horvath J, Bouvagnet P, Witmer PD, MacCarrick G, Cisarova K, Good JM, Gorokhova S, Boute O, Smol T, Bruel AL, Patat O, Broadbent JR, Tan TY, Tan NB, Lyonnet S, Busa T, Graziano C, Amiel J, Gordon CT. Bi-allelic MED16 variants cause a MEDopathy with intellectual disability, motor delay, and craniofacial, cardiac, and limb malformations. Am J Hum Genet. 2025 Apr 03; 112(4):829-845.
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