 Genes, Essential
"Genes, Essential" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Those genes found in an organism which are necessary for its viability and normal function.
| Descriptor ID |
D020043
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| MeSH Number(s) |
G05.360.340.024.340.270
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| Concept/Terms |
Genes, Housekeeping- Genes, Housekeeping
- Gene, Housekeeping
- Housekeeping Gene
- Housekeeping Genes
- Genes, House-keeping
- Gene, House-keeping
- Genes, House keeping
- House-keeping Gene
- House-keeping Genes
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Below are MeSH descriptors whose meaning is more general than "Genes, Essential".
Below are MeSH descriptors whose meaning is more specific than "Genes, Essential".
This graph shows the total number of publications written about "Genes, Essential" by people in this website by year, and whether "Genes, Essential" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 2 | 2 | | 2012 | 3 | 0 | 3 | | 2013 | 1 | 0 | 1 | | 2014 | 0 | 4 | 4 | | 2015 | 1 | 1 | 2 | | 2017 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 0 | 2 | 2 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Genes, Essential" by people in Profiles.
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Choudhury A, Fenster JA, Fankhauser RG, Kaar JL, Tenaillon O, Gill RT. CRISPR/Cas9 recombineering-mediated deep mutational scanning of essential genes in Escherichia coli. Mol Syst Biol. 2020 Mar; 16(3):e9265.
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Kim J, Flood JJ, Kristofich MR, Gidfar C, Morgenthaler AB, Fuhrer T, Sauer U, Snyder D, Cooper VS, Ebmeier CC, Old WM, Copley SD. Hidden resources in the Escherichia coli genome restore PLP synthesis and robust growth after deletion of the essential gene pdxB. Proc Natl Acad Sci U S A. 2019 11 26; 116(48):24164-24173.
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Towers CG, Fitzwalter BE, Regan D, Goodspeed A, Morgan MJ, Liu CW, Gustafson DL, Thorburn A. Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition. Dev Cell. 2019 09 23; 50(6):690-703.e6.
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Poulsen BE, Yang R, Clatworthy AE, White T, Osmulski SJ, Li L, Penaranda C, Lander ES, Shoresh N, Hung DT. Defining the core essential genome of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 2019 05 14; 116(20):10072-10080.
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Ladam F, Stanney W, Donaldson IJ, Yildiz O, Bobola N, Sagerstr?m CG. TALE factors use two distinct functional modes to control an essential zebrafish gene expression program. Elife. 2018 06 18; 7.
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Singleton KR, Earley KT, Heasley LE. Analysis of Drug Resistance Using Kinome-Wide Functional Screens. Methods Mol Biol. 2017; 1636:163-177.
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Hart T, Chandrashekhar M, Aregger M, Steinhart Z, Brown KR, MacLeod G, Mis M, Zimmermann M, Fradet-Turcotte A, Sun S, Mero P, Dirks P, Sidhu S, Roth FP, Rissland OS, Durocher D, Angers S, Moffat J. High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities. Cell. 2015 Dec 03; 163(6):1515-26.
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Singleton KR, Hinz TK, Kleczko EK, Marek LA, Kwak J, Harp T, Kim J, Tan AC, Heasley LE. Kinome RNAi Screens Reveal Synergistic Targeting of MTOR and FGFR1 Pathways for Treatment of Lung Cancer and HNSCC. Cancer Res. 2015 Oct 15; 75(20):4398-406.
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Lorberbaum DS, Barolo S. Enhancers: holding out for the right promoter. Curr Biol. 2015 Mar 30; 25(7):R290-3.
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Kim J, Webb AM, Kershner JP, Blaskowski S, Copley SD. A versatile and highly efficient method for scarless genome editing in Escherichia coli and Salmonella enterica. BMC Biotechnol. 2014 Sep 25; 14:84.
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