 Genes, RAG-1
"Genes, RAG-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes involved in activating the enzyme VDJ recombinase. RAG-1 is located on chromosome 11 in humans (chromosome 2 in mice) and is expressed exclusively in maturing lymphocytes.
| Descriptor ID |
D016654
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| MeSH Number(s) |
G05.360.340.024.340.400
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| Concept/Terms |
Genes, RAG-1- Genes, RAG-1
- Genes, RAG 1
- Recombination-Activating Genes-1
- Recombination Activating Genes 1
- Recombination-Activating Gene-1
- Recombination Activating Gene 1
- RAG-1 Genes
- Gene, RAG-1
- RAG 1 Genes
- RAG-1 Gene
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Below are MeSH descriptors whose meaning is more general than "Genes, RAG-1".
Below are MeSH descriptors whose meaning is more specific than "Genes, RAG-1".
This graph shows the total number of publications written about "Genes, RAG-1" by people in this website by year, and whether "Genes, RAG-1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, RAG-1" by people in Profiles.
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Plenter RJ, Grazia TJ, Nelson DP, Zamora MR, Gill RG, Pietra BA. Ectopic expression of Fas Ligand on cardiomyocytes renders cardiac allografts resistant to CD4(+) T-cell mediated rejection. Cell Immunol. 2015 Jan; 293(1):30-3.
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Weckbach S, Neher M, Losacco JT, Bolden AL, Kulik L, Flierl MA, Bell SE, Holers VM, Stahel PF. Challenging the role of adaptive immunity in neurotrauma: Rag1(-/-) mice lacking mature B and T cells do not show neuroprotection after closed head injury. J Neurotrauma. 2012 Apr 10; 29(6):1233-42.
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Khan MA, Jiang X, Dhillon G, Beilke J, Holers VM, Atkinson C, Tomlinson S, Nicolls MR. CD4+ T cells and complement independently mediate graft ischemia in the rejection of mouse orthotopic tracheal transplants. Circ Res. 2011 Nov 11; 109(11):1290-301.
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Aggarwal NR, D'Alessio FR, Tsushima K, Sidhaye VK, Cheadle C, Grigoryev DN, Barnes KC, King LS. Regulatory T cell-mediated resolution of lung injury: identification of potential target genes via expression profiling. Physiol Genomics. 2010 Apr 01; 41(2):109-19.
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Spellman GM, Cibois A, Moyle RG, Winker K, Keith Barker F. Clarifying the systematics of an enigmatic avian lineage: what is a bombycillid? Mol Phylogenet Evol. 2008 Dec; 49(3):1036-40.
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Jasinski JM, Yu L, Nakayama M, Li MM, Lipes MA, Eisenbarth GS, Liu E. Transgenic insulin (B:9-23) T-cell receptor mice develop autoimmune diabetes dependent upon RAG genotype, H-2g7 homozygosity, and insulin 2 gene knockout. Diabetes. 2006 Jul; 55(7):1978-84.
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Vaitaitis GM, Poulin M, Sanderson RJ, Haskins K, Wagner DH. Cutting edge: CD40-induced expression of recombination activating gene (RAG) 1 and RAG2: a mechanism for the generation of autoaggressive T cells in the periphery. J Immunol. 2003 Apr 01; 170(7):3455-9.
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Durum SK, Cand?ias S, Nakajima H, Leonard WJ, Baird AM, Berg LJ, Muegge K. Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: role of receptor-associated chains and locus accessibility. J Exp Med. 1998 Dec 21; 188(12):2233-41.
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Papavasiliou F, Casellas R, Suh H, Qin XF, Besmer E, Pelanda R, Nemazee D, Rajewsky K, Nussenzweig MC. V(D)J recombination in mature B cells: a mechanism for altering antibody responses. Science. 1997 Oct 10; 278(5336):298-301.
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