CD28 Antigens
"CD28 Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Costimulatory T-LYMPHOCYTE receptors that have specificity for CD80 ANTIGEN and CD86 ANTIGEN. Activation of this receptor results in increased T-cell proliferation, cytokine production and promotion of T-cell survival.
Descriptor ID |
D018106
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MeSH Number(s) |
D12.776.543.750.705.222.500 D23.050.301.264.894.128 D23.101.100.894.128
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Concept/Terms |
CD28 Antigens- CD28 Antigens
- TP44 Receptor
- Receptor, TP44
- T-Cell-Specific Surface Glycoprotein CD28
- T Cell Specific Surface Glycoprotein CD28
- CD28 Antigen
- Antigen, CD28
- Antigens, CD28
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Below are MeSH descriptors whose meaning is more general than "CD28 Antigens".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Costimulatory and Inhibitory T-Cell Receptors [D12.776.543.750.705.222]
- CD28 Antigens [D12.776.543.750.705.222.500]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, Differentiation, T-Lymphocyte [D23.050.301.264.894]
- CD28 Antigens [D23.050.301.264.894.128]
- Biomarkers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, Differentiation, T-Lymphocyte [D23.101.100.894]
- CD28 Antigens [D23.101.100.894.128]
Below are MeSH descriptors whose meaning is more specific than "CD28 Antigens".
This graph shows the total number of publications written about "CD28 Antigens" by people in this website by year, and whether "CD28 Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 | 1997 | 1 | 0 | 1 | 1998 | 0 | 3 | 3 | 1999 | 0 | 1 | 1 | 2000 | 0 | 2 | 2 | 2001 | 0 | 1 | 1 | 2003 | 1 | 0 | 1 | 2004 | 0 | 1 | 1 | 2005 | 2 | 2 | 4 | 2006 | 0 | 1 | 1 | 2007 | 0 | 1 | 1 | 2008 | 0 | 4 | 4 | 2009 | 2 | 2 | 4 | 2011 | 1 | 2 | 3 | 2013 | 2 | 2 | 4 | 2015 | 0 | 1 | 1 | 2016 | 0 | 1 | 1 | 2017 | 0 | 1 | 1 | 2018 | 0 | 1 | 1 | 2019 | 0 | 1 | 1 | 2023 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "CD28 Antigens" by people in Profiles.
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Lui VG, Hoenig M, Cabrera-Martinez B, Baxter RM, Garcia-Perez JE, Bailey O, Acharya A, Lundquist K, Capera J, Matusewicz P, Hartl FA, D'Abramo M, Alba J, Jacobsen EM, Niewolik D, Lorenz M, Pannicke U, Schulz AS, Debatin KM, Schamel WW, Minguet S, Gumbart JC, Dustin ML, Cambier JC, Schwarz K, Hsieh EWY. A partial human LCK defect causes a T cell immunodeficiency with intestinal inflammation. J Exp Med. 2024 Jan 01; 221(1).
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Seamans BN, Pellechio SL, Capria AL, Agyingi SE, Morenikeji OB, Ojurongbe O, Thomas BN. Genetic diversity of CD14, CD28, CTLA-4 and ICOS gene promoter polymorphism in African and American sickle cell disease. Hum Immunol. 2019 Nov; 80(11):930-936.
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Plenter RJ, Grazia TJ, Coulombe MG, Nelsen MK, Lin CM, Scott Beard K, Kupfer TM, Zamora MR, Gill RG, Pietra BA. Anti-LFA-1 induces CD8 T-cell dependent allograft tolerance and augments suppressor phenotype CD8 cells. Cell Immunol. 2018 10; 332:101-110.
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Vaitaitis GM, Waid DM, Yussman MG, Wagner DH. CD40-mediated signalling influences trafficking, T-cell receptor expression, and T-cell pathogenesis, in the NOD model of type 1 diabetes. Immunology. 2017 10; 152(2):243-254.
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Kumar S, Gautam PK, Tomar MS, Acharya A. CD28-mediated T cell response is upregulated by exogenous application of autologous Hsp70-peptide complex in a tumor-bearing host. Immunol Res. 2016 Feb; 64(1):313-23.
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Long AH, Haso WM, Shern JF, Wanhainen KM, Murgai M, Ingaramo M, Smith JP, Walker AJ, Kohler ME, Venkateshwara VR, Kaplan RN, Patterson GH, Fry TJ, Orentas RJ, Mackall CL. 4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors. Nat Med. 2015 Jun; 21(6):581-90.
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Chung EH, Jia Y, Ohnishi H, Takeda K, Leung DY, Sutherland ER, Dakhama A, Martin RJ, Gelfand EW. Leukotriene B4 receptor 1 is differentially expressed on peripheral T cells of steroid-sensitive and -resistant asthmatics. Ann Allergy Asthma Immunol. 2014 Mar; 112(3):211-216.e1.
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Jain N, Miu B, Jiang JK, McKinstry KK, Prince A, Swain SL, Greiner DL, Thomas CJ, Sanderson MJ, Berg LJ, Kang J. CD28 and ITK signals regulate autoreactive T cell trafficking. Nat Med. 2013 Dec; 19(12):1632-7.
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Joosten LA, Netea MG, Dinarello CA. Interleukin-1? in innate inflammation, autophagy and immunity. Semin Immunol. 2013 Dec 15; 25(6):416-24.
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Chain JL, Martin AK, Mack DG, Maier LA, Palmer BE, Fontenot AP. Impaired function of CTLA-4 in the lungs of patients with chronic beryllium disease contributes to persistent inflammation. J Immunol. 2013 Aug 15; 191(4):1648-56.
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