 CD5 Antigens
"CD5 Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycoproteins expressed on all mature T-cells, thymocytes, and a subset of mature B-cells. Antibodies specific for CD5 can enhance T-cell receptor-mediated T-cell activation. The B-cell-specific molecule CD72 is a natural ligand for CD5. (From Abbas et al., Cellular and Molecular Immunology, 2d ed, p156)
| Descriptor ID |
D018956
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| MeSH Number(s) |
D23.050.301.264.051.101 D23.050.301.264.894.101 D23.101.100.150.101 D23.101.100.894.101
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| Concept/Terms |
CD5 Antigens- CD5 Antigens
- T1 Antigen
- Leu-1 Antigen
- Leu 1 Antigen
- CD5 Antigen
- Antigen, CD5
- Antigens, CD5
|
Below are MeSH descriptors whose meaning is more general than "CD5 Antigens".
- Chemicals and Drugs [D]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, Differentiation, B-Lymphocyte [D23.050.301.264.051]
- CD5 Antigens [D23.050.301.264.051.101]
- Antigens, Differentiation, T-Lymphocyte [D23.050.301.264.894]
- CD5 Antigens [D23.050.301.264.894.101]
- Biomarkers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, Differentiation, B-Lymphocyte [D23.101.100.150]
- CD5 Antigens [D23.101.100.150.101]
- Antigens, Differentiation, T-Lymphocyte [D23.101.100.894]
- CD5 Antigens [D23.101.100.894.101]
Below are MeSH descriptors whose meaning is more specific than "CD5 Antigens".
This graph shows the total number of publications written about "CD5 Antigens" by people in this website by year, and whether "CD5 Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "CD5 Antigens" by people in Profiles.
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Zhang M, Zheng X, Zhang J, Zhu Y, Zhu X, Liu H, Zeng M, Graner MW, Zhou B, Chen X. CD19(+)CD1d(+)CD5(+) B cell frequencies are increased in patients with tuberculosis and suppress Th17 responses. Cell Immunol. 2012; 274(1-2):89-97.
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Marshall CB, Jacob B, Patel S, Sneige N, Jimenez CA, Morice RC, Caraway N. The utility of endobronchial ultrasound-guided transbronchial needle aspiration biopsy in the diagnosis of mediastinal lymphoproliferative disorders. Cancer Cytopathol. 2011 Apr 25; 119(2):118-26.
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Lenz LL. CD5 sweetens lymphocyte responses. Proc Natl Acad Sci U S A. 2009 Feb 03; 106(5):1303-4.
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Kupfer R, Lang J, Williams-Skipp C, Nelson M, Bellgrau D, Scheinman RI. Loss of a gimap/ian gene leads to activation of NF-kappaB through a MAPK-dependent pathway. Mol Immunol. 2007 Jan; 44(4):479-87.
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Dal Porto JM, Burke K, Cambier JC. Regulation of BCR signal transduction in B-1 cells requires the expression of the Src family kinase Lck. Immunity. 2004 Sep; 21(3):443-53.
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Curry MP, Golden-Mason L, Doherty DG, Deignan T, Norris S, Duffy M, Nolan N, Hall W, Hegarty JE, O'Farrelly C. Expansion of innate CD5pos B cells expressing high levels of CD81 in hepatitis C virus infected liver. J Hepatol. 2003 May; 38(5):642-50.
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Elphick GF, Wieseler-Frank J, Greenwood BN, Campisi J, Fleshner M. B-1 cell (CD5+/CD11b+) numbers and nIgM levels are elevated in physically active vs. sedentary rats. J Appl Physiol (1985). 2003 Jul; 95(1):199-206.
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Bhandoola A, Bosselut R, Yu Q, Cowan ML, Feigenbaum L, Love PE, Singer A. CD5-mediated inhibition of TCR signaling during intrathymic selection and development does not require the CD5 extracellular domain. Eur J Immunol. 2002 Jun; 32(6):1811-7.
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O'Neill LA, Dinarello CA. The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense. Immunol Today. 2000 May; 21(5):206-9.
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Chumley MJ, Dal Porto JM, Kawaguchi S, Cambier JC, Nemazee D, Hardy RR. A VH11V kappa 9 B cell antigen receptor drives generation of CD5+ B cells both in vivo and in vitro. J Immunol. 2000 May 01; 164(9):4586-93.
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