CD8 Antigens
"CD8 Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Differentiation antigens found on thymocytes and on cytotoxic and suppressor T-lymphocytes. T8 antigens are members of the immunoglobulin supergene family and are associative recognition elements in MHC (Major Histocompatibility Complex) Class I-restricted interactions.
Descriptor ID |
D016827
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MeSH Number(s) |
D23.050.301.264.894.108 D23.101.100.894.108
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Concept/Terms |
CD8 Antigens- CD8 Antigens
- T8 Antigens, T-Cell
- Antigens, T-Cell T8
- T-Cell T8 Antigens
- T8 Antigens, T Cell
- Leu-2 Antigens
- Antigens, Leu-2
- Leu 2 Antigens
- CD8 Antigen
- Antigen, CD8
- Antigens, CD8
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Below are MeSH descriptors whose meaning is more general than "CD8 Antigens".
Below are MeSH descriptors whose meaning is more specific than "CD8 Antigens".
This graph shows the total number of publications written about "CD8 Antigens" by people in this website by year, and whether "CD8 Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 3 | 4 | 1996 | 0 | 1 | 1 | 1999 | 1 | 0 | 1 | 2001 | 1 | 0 | 1 | 2002 | 1 | 1 | 2 | 2003 | 0 | 3 | 3 | 2005 | 1 | 2 | 3 | 2006 | 1 | 1 | 2 | 2007 | 0 | 3 | 3 | 2008 | 1 | 1 | 2 | 2009 | 0 | 1 | 1 | 2011 | 0 | 1 | 1 | 2013 | 1 | 0 | 1 | 2015 | 1 | 1 | 2 | 2017 | 1 | 0 | 1 | 2019 | 1 | 0 | 1 | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "CD8 Antigens" by people in Profiles.
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Yomogida K, Trsan T, Sudan R, Rodrigues PF, Ulezko Antonova A, Ingle H, Luccia BD, Collins PL, Cella M, Gilfillan S, Baldridge MT, Oltz EM, Colonna M. The transcription factor Aiolos restrains the activation of intestinal intraepithelial lymphocytes. Nat Immunol. 2024 Jan; 25(1):77-87.
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Cross EW, Blain TJ, Mathew D, Kedl RM. Anti-CD8 monoclonal antibody-mediated depletion alters the phenotype and behavior of surviving CD8+ T cells. PLoS One. 2019; 14(2):e0211446.
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Kaczanowska S, Joseph AM, Guo J, Tsai AK, Lasola JJ, Younger K, Zhang Y, Gonzales CV, Davila E. A Synthetic CD8a:MyD88 Coreceptor Enhances CD8+ T-cell Responses to Weakly Immunogenic and Lowly Expressed Tumor Antigens. Cancer Res. 2017 12 15; 77(24):7049-7058.
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Yanik EL, Kaunitz GJ, Cottrell TR, Succaria F, McMiller TL, Ascierto ML, Esandrio J, Xu H, Ogurtsova A, Cornish T, Lipson EJ, Topalian SL, Engels EA, Taube JM. Association of HIV Status With Local Immune Response to Anal Squamous Cell Carcinoma: Implications for Immunotherapy. JAMA Oncol. 2017 Jul 01; 3(7):974-978.
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Mishra AK, Kadoishi T, Wang X, Driver E, Chen Z, Wang XJ, Wang JH. Squamous cell carcinomas escape immune surveillance via inducing chronic activation and exhaustion of CD8+ T Cells co-expressing PD-1 and LAG-3 inhibitory receptors. Oncotarget. 2016 Dec 06; 7(49):81341-81356.
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Legein B, Janssen EM, Theelen TL, Gijbels MJ, Walraven J, Klarquist JS, Hennies CM, Wouters K, Seijkens TT, Wijnands E, Sluimer JC, Lutgens E, Zenke M, Hildner K, Biessen EA, Temmerman L. Ablation of CD8a(+) dendritic cell mediated cross-presentation does not impact atherosclerosis in hyperlipidemic mice. Sci Rep. 2015 Oct 21; 5:15414.
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Torkko KC, Wilson RS, Smith EE, Kusek JW, van Bokhoven A, Lucia MS. Prostate Biopsy Markers of Inflammation are Associated with Risk of Clinical Progression of Benign Prostatic Hyperplasia: Findings from the MTOPS Study. J Urol. 2015 Aug; 194(2):454-61.
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Sosinowski T, White JT, Cross EW, Haluszczak C, Marrack P, Gapin L, Kedl RM. CD8a+ dendritic cell trans presentation of IL-15 to naive CD8+ T cells produces antigen-inexperienced T cells in the periphery with memory phenotype and function. J Immunol. 2013 Mar 01; 190(5):1936-47.
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Baker K, Qiao SW, Kuo TT, Aveson VG, Platzer B, Andersen JT, Sandlie I, Chen Z, de Haar C, Lencer WI, Fiebiger E, Blumberg RS. Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells. Proc Natl Acad Sci U S A. 2011 Jun 14; 108(24):9927-32.
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Weinberg A, Enomoto L, Marcus R, Canniff J. Effect of menstrual cycle variation in female sex hormones on cellular immunity and regulation. J Reprod Immunol. 2011 Apr; 89(1):70-7.
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