Excitation Contraction Coupling
"Excitation Contraction Coupling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A process fundamental to muscle physiology whereby an electrical stimulus or action potential triggers a myocyte to depolarize and contract. This mechanical muscle contraction response is regulated by entry of calcium ions into the cell.
Descriptor ID |
D056966
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MeSH Number(s) |
G02.111.820.800.100.500 G04.835.199 G11.427.494.235
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Concept/Terms |
Excitation Contraction Coupling- Excitation Contraction Coupling
- Contraction Coupling, Excitation
- Contraction Couplings, Excitation
- Coupling, Excitation Contraction
- Couplings, Excitation Contraction
- Excitation Contraction Couplings
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Below are MeSH descriptors whose meaning is more general than "Excitation Contraction Coupling".
Below are MeSH descriptors whose meaning is more specific than "Excitation Contraction Coupling".
This graph shows the total number of publications written about "Excitation Contraction Coupling" by people in this website by year, and whether "Excitation Contraction Coupling" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2010 | 1 | 2 | 3 | 2011 | 0 | 1 | 1 | 2012 | 1 | 0 | 1 | 2013 | 0 | 1 | 1 | 2014 | 0 | 1 | 1 | 2015 | 1 | 0 | 1 | 2016 | 2 | 0 | 2 | 2017 | 0 | 2 | 2 | 2018 | 2 | 0 | 2 | 2020 | 1 | 0 | 1 | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Excitation Contraction Coupling" by people in Profiles.
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Dayal A, Perni S, Franzini-Armstrong C, Beam KG, Grabner M. The distal C terminus of the dihydropyridine receptor ?1a subunit is essential for tetrad formation in skeletal muscle. Proc Natl Acad Sci U S A. 2022 05 10; 119(19):e2201136119.
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Rog-Zielinska EA, Scardigli M, Peyronnet R, Zgierski-Johnston CM, Greiner J, Madl J, O'Toole ET, Morphew M, Hoenger A, Sacconi L, Kohl P. Beat-by-Beat Cardiomyocyte T-Tubule Deformation Drives Tubular Content Exchange. Circ Res. 2021 01 22; 128(2):203-215.
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Guo A, Wang Y, Chen B, Wang Y, Yuan J, Zhang L, Hall D, Wu J, Shi Y, Zhu Q, Chen C, Thiel WH, Zhan X, Weiss RM, Zhan F, Musselman CA, Pufall M, Zhu W, Au KF, Hong J, Anderson ME, Grueter CE, Song LS. E-C coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator. Science. 2018 12 21; 362(6421).
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Polster A, Nelson BR, Papadopoulos S, Olson EN, Beam KG. Stac proteins associate with the critical domain for excitation-contraction coupling in the II-III loop of CaV1.1. J Gen Physiol. 2018 04 02; 150(4):613-624.
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Scardigli M, Crocini C, Ferrantini C, Gabbrielli T, Silvestri L, Coppini R, Tesi C, Rog-Zielinska EA, Kohl P, Cerbai E, Poggesi C, Pavone FS, Sacconi L. Quantitative assessment of passive electrical properties of the cardiac T-tubular system by FRAP microscopy. Proc Natl Acad Sci U S A. 2017 05 30; 114(22):5737-5742.
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Coppini R, Mazzoni L, Ferrantini C, Gentile F, Pioner JM, Laurino A, Santini L, Bargelli V, Rotellini M, Bartolucci G, Crocini C, Sacconi L, Tesi C, Belardinelli L, Tardiff J, Mugelli A, Olivotto I, Cerbai E, Poggesi C. Ranolazine Prevents Phenotype Development in a Mouse Model of Hypertrophic Cardiomyopathy. Circ Heart Fail. 2017 03; 10(3).
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Wang H, Zhang X, Dorsey SM, McGarvey JR, Campbell KS, Burdick JA, Gorman JH, Pilla JJ, Gorman RC, Wenk JF. Computational Investigation of Transmural Differences in Left Ventricular Contractility. J Biomech Eng. 2016 11 01; 138(11).
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Polster A, Nelson BR, Olson EN, Beam KG. Stac3 has a direct role in skeletal muscle-type excitation-contraction coupling that is disrupted by a myopathy-causing mutation. Proc Natl Acad Sci U S A. 2016 09 27; 113(39):10986-91.
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Beqollari D, Romberg CF, Dobrowolny G, Martini M, Voss AA, Musar? A, Bannister RA. Progressive impairment of CaV1.1 function in the skeletal muscle of mice expressing a mutant type 1 Cu/Zn superoxide dismutase (G93A) linked to amyotrophic lateral sclerosis. Skelet Muscle. 2016; 6:24.
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Pioner JM, Racca AW, Klaiman JM, Yang KC, Guan X, Pabon L, Muskheli V, Zaunbrecher R, Macadangdang J, Jeong MY, Mack DL, Childers MK, Kim DH, Tesi C, Poggesi C, Murry CE, Regnier M. Isolation and Mechanical Measurements of Myofibrils from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Stem Cell Reports. 2016 06 14; 6(6):885-896.
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