 Aggrecans
"Aggrecans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Large HYALURONAN-containing proteoglycans found in articular cartilage (CARTILAGE, ARTICULAR). They form into aggregates that provide tissues with the capacity to resist high compressive and tensile forces.
| Descriptor ID |
D053674
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| MeSH Number(s) |
D09.698.735.200.500 D12.776.395.650.750.687.100 D12.776.503.280.437.100 D12.776.860.300.140
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| Concept/Terms |
Aggrecans- Aggrecans
- Cartilage-Specific Proteoglycan Core Proteins
- Cartilage Specific Proteoglycan Core Proteins
- Aggrecan
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Below are MeSH descriptors whose meaning is more general than "Aggrecans".
Below are MeSH descriptors whose meaning is more specific than "Aggrecans".
This graph shows the total number of publications written about "Aggrecans" by people in this website by year, and whether "Aggrecans" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2009 | 1 | 1 | 2 | | 2011 | 0 | 1 | 1 | | 2012 | 1 | 2 | 3 | | 2014 | 1 | 1 | 2 | | 2019 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aggrecans" by people in Profiles.
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Wang P, Xu J, Sun Q, Ge Q, Qiu M, Zou K, Ying J, Yuan W, Chen J, Zeng Q, Cui Q, Jin H, Zhang C, Li F. Chondroprotective Mechanism of Eucommia ulmoides Oliv.-Glycyrrhiza uralensis Fisch. Couplet Medicines in Knee Osteoarthritis via Experimental Study and Network Pharmacology Analysis. Drug Des Devel Ther. 2023; 17:633-646.
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Chubinskaya S, Cotter EJ, Frank RM, Hakimiyan AA, Yanke AB, Cole BJ. Biologic Characteristics of Shoulder Articular Cartilage in Comparison to Knee and Ankle Articular Cartilage From Individual Donors. Cartilage. 2021 10; 12(4):456-467.
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Davis HC, Spang JT, Loeser RF, Larsson S, Ulici V, Troy Blackburn J, Creighton RA, Kamath GM, Jordan JM, Marshall SW, Pietrosimone B. Time between anterior cruciate ligament injury and reconstruction and cartilage metabolism six-months following reconstruction. Knee. 2018 Mar; 25(2):296-305.
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Skaalure SC, Chu S, Bryant SJ. An enzyme-sensitive PEG hydrogel based on aggrecan catabolism for cartilage tissue engineering. Adv Healthc Mater. 2015 Feb 18; 4(3):420-31.
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Illien-J?nger S, Lu Y, Purmessur D, Mayer JE, Walter BA, Roughley PJ, Qureshi SA, Hecht AC, Iatridis JC. Detrimental effects of discectomy on intervertebral disc biology can be decelerated by growth factor treatment during surgery: a large animal organ culture model. Spine J. 2014 Nov 01; 14(11):2724-32.
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Sharma S, Panitch A, Neu CP. Incorporation of an aggrecan mimic prevents proteolytic degradation of anisotropic cartilage analogs. Acta Biomater. 2013 Jan; 9(1):4618-25.
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Farnsworth N, Bensard C, Bryant SJ. The role of the PCM in reducing oxidative stress induced by radical initiated photoencapsulation of chondrocytes in poly(ethylene glycol) hydrogels. Osteoarthritis Cartilage. 2012 Nov; 20(11):1326-35.
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Steinmetz NJ, Bryant SJ. Chondroitin sulfate and dynamic loading alter chondrogenesis of human MSCs in PEG hydrogels. Biotechnol Bioeng. 2012 Oct; 109(10):2671-82.
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Bian L, Zhai DY, Zhang EC, Mauck RL, Burdick JA. Dynamic compressive loading enhances cartilage matrix synthesis and distribution and suppresses hypertrophy in hMSC-laden hyaluronic acid hydrogels. Tissue Eng Part A. 2012 Apr; 18(7-8):715-24.
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Vidal AF. Commentary on an article by Gaetano J. Scuderi, MD, et al.: "Identification of a novel fibronectin-aggrecan complex in the synovial fluid of knees with painful meniscal injury". J Bone Joint Surg Am. 2011 Feb 16; 93(4):e13.
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