 5' Flanking Region
"5' Flanking Region" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The region of DNA which borders the 5' end of a transcription unit and where a variety of regulatory sequences are located.
| Descriptor ID |
D024506
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| MeSH Number(s) |
G05.360.340.024.220.282 G05.360.340.024.340.137.295
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| Concept/Terms |
5' Flanking Region- 5' Flanking Region
- 5' Flanking Regions
- Flanking Regions, 5'
- Region, 5' Flanking
- Regions, 5' Flanking
- Flanking Region, 5'
- 5' Flanking Sequence
- 5' Flanking Sequences
- Flanking Sequence, 5'
- Flanking Sequences, 5'
- Sequence, 5' Flanking
- Sequences, 5' Flanking
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Below are MeSH descriptors whose meaning is more general than "5' Flanking Region".
Below are MeSH descriptors whose meaning is more specific than "5' Flanking Region".
This graph shows the total number of publications written about "5' Flanking Region" by people in this website by year, and whether "5' Flanking Region" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2008 | 2 | 1 | 3 | | 2010 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "5' Flanking Region" by people in Profiles.
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Donaldson ZR, Young LJ. The relative contribution of proximal 5' flanking sequence and microsatellite variation on brain vasopressin 1a receptor (Avpr1a) gene expression and behavior. PLoS Genet. 2013 Aug; 9(8):e1003729.
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Hopkins WD, Donaldson ZR, Young LJ. A polymorphic indel containing the RS3 microsatellite in the 5' flanking region of the vasopressin V1a receptor gene is associated with chimpanzee (Pan troglodytes) personality. Genes Brain Behav. 2012 Jul; 11(5):552-8.
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Raum JC, Hunter CS, Artner I, Henderson E, Guo M, Elghazi L, Sosa-Pineda B, Ogihara T, Mirmira RG, Sussel L, Stein R. Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain. Mol Cell Biol. 2010 Sep; 30(17):4234-44.
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Singh A, Ling G, Suhasini AN, Zhang P, Yamamoto M, Navas-Acien A, Cosgrove G, Tuder RM, Kensler TW, Watson WH, Biswal S. Nrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs. Free Radic Biol Med. 2009 Feb 01; 46(3):376-86.
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Donaldson ZR, Kondrashov FA, Putnam A, Bai Y, Stoinski TL, Hammock EA, Young LJ. Evolution of a behavior-linked microsatellite-containing element in the 5' flanking region of the primate AVPR1A gene. BMC Evol Biol. 2008 Jun 23; 8:180.
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Wang H, Sammel MD, Tromp G, Gotsch F, Halder I, Shriver MD, Romero R, Strauss JF. A 12-bp deletion in the 5'-flanking region of the SERPINH1 gene affects promoter activity and protects against preterm premature rupture of membranes in African Americans. Hum Mutat. 2008 Feb; 29(2):332.
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Britton RA, Wen T, Schaefer L, Pellegrini O, Uicker WC, Mathy N, Tobin C, Daou R, Szyk J, Condon C. Maturation of the 5' end of Bacillus subtilis 16S rRNA by the essential ribonuclease YkqC/RNase J1. Mol Microbiol. 2007 Jan; 63(1):127-38.
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Morris KR, Lutz RD, Choi HS, Kamitani T, Chmura K, Chan ED. Role of the NF-kappaB signaling pathway and kappaB cis-regulatory elements on the IRF-1 and iNOS promoter regions in mycobacterial lipoarabinomannan induction of nitric oxide. Infect Immun. 2003 Mar; 71(3):1442-52.
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Mogayzel PJ, Esmail M, Wagner TL, Zeitlin PL, Ashlock M. cis-Acting elements within CFTR 5'-flanking DNA are not sufficient to decrease gene expression in response to phorbol ester. Biochim Biophys Acta. 2002 Jul 19; 1576(3):306-15.
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