 Open Reading Frames
"Open Reading Frames" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sequence of successive nucleotide triplets that are read as CODONS specifying AMINO ACIDS and begin with an INITIATOR CODON and end with a stop codon (CODON, TERMINATOR).
| Descriptor ID |
D016366
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| MeSH Number(s) |
G05.360.335.760.640 G05.360.340.024.340.137.650
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| Concept/Terms |
Open Reading Frames- Open Reading Frames
- Frame, Open Reading
- Frames, Open Reading
- Open Reading Frame
- Reading Frame, Open
- Reading Frames, Open
- ORFs
- Protein Coding Region
- Coding Region, Protein
- Coding Regions, Protein
- Protein Coding Regions
- Region, Protein Coding
- Regions, Protein Coding
Unassigned Reading Frames- Unassigned Reading Frames
- Frame, Unassigned Reading
- Frames, Unassigned Reading
- Reading Frame, Unassigned
- Reading Frames, Unassigned
- Unassigned Reading Frame
- Unidentified Reading Frame
- Frame, Unidentified Reading
- Frames, Unidentified Reading
- Reading Frame, Unidentified
- Reading Frames, Unidentified
- Unidentified Reading Frames
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Below are MeSH descriptors whose meaning is more general than "Open Reading Frames".
Below are MeSH descriptors whose meaning is more specific than "Open Reading Frames".
This graph shows the total number of publications written about "Open Reading Frames" by people in this website by year, and whether "Open Reading Frames" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1999 | 0 | 2 | 2 | | 2000 | 1 | 4 | 5 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 2 | 2 | | 2004 | 1 | 4 | 5 | | 2005 | 0 | 4 | 4 | | 2006 | 1 | 3 | 4 | | 2007 | 2 | 3 | 5 | | 2008 | 1 | 3 | 4 | | 2009 | 0 | 4 | 4 | | 2010 | 1 | 2 | 3 | | 2011 | 2 | 4 | 6 | | 2012 | 3 | 3 | 6 | | 2013 | 2 | 7 | 9 | | 2014 | 1 | 2 | 3 | | 2015 | 0 | 5 | 5 | | 2016 | 1 | 2 | 3 | | 2017 | 0 | 3 | 3 | | 2018 | 2 | 4 | 6 | | 2019 | 2 | 4 | 6 | | 2020 | 0 | 1 | 1 | | 2021 | 2 | 3 | 5 | | 2023 | 0 | 3 | 3 | | 2024 | 2 | 4 | 6 | | 2025 | 2 | 0 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Open Reading Frames" by people in Profiles.
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Walters K, Castro-Gutierrez R, Sarkar S, Baldwin A, Baker AS, Shilleh AH, Anderson AM, Nakayama M, Fugman T, Nakayasu ES, Mukherjee N, Russ HA. Proteogenomic Discovery of Novel Open Reading Frames With HLA Immune Presentation on Human ß-Cells. Diabetes. 2025 Dec 01; 74(12):2322-2336.
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Tonsager AJ, Zukowski A, Radebaugh CA, Weirich A, Stargell LA, Ramachandran S. The histone chaperone Spn1 preserves chromatin protections at promoters and nucleosome positioning in open reading frames. G3 (Bethesda). 2025 Apr 17; 15(4).
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Patiño-Galindo J, García-Sastre A, Kuhn JH, Rabadan R, Palacios G. Recombination across distant coronavirid species and genera is a rare event with distinct genomic features. J Virol. 2024 12 17; 98(12):e0110024.
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Whited AM, Jungreis I, Allen J, Cleveland CL, Mudge JM, Kellis M, Rinn JL, Hough LE. Biophysical characterization of high-confidence, small human proteins. Biophys Rep (N Y). 2024 Sep 11; 4(3):100167.
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Kuhn JH, Botella L, de la Peña M, Vainio EJ, Krupovic M, Lee BD, Navarro B, Sabanadzovic S, Simmonds P, Turina M. Ambiviricota, a novel ribovirian phylum for viruses with viroid-like properties. J Virol. 2024 Jul 23; 98(7):e0083124.
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Musaev D, Abdelmessih M, Vejnar CE, Yartseva V, Weiss LA, Strayer EC, Takacs CM, Giraldez AJ. UPF1 regulates mRNA stability by sensing poorly translated coding sequences. Cell Rep. 2024 04 23; 43(4):114074.
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Bradfute SB, Calisher CH, Klempa B, Klingström J, Kuhn JH, Laenen L, Tischler ND, Maes P. ICTV Virus Taxonomy Profile: Hantaviridae 2024. J Gen Virol. 2024 04; 105(4).
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Kuhn JH, Alkhovsky SV, Av?ic-?upanc T, Bergeron É, Burt F, Ergünay K, Garrison AR, Marklewitz M, Mirazimi A, Papa A, Paweska JT, Spengler JR, Palacios G. ICTV Virus Taxonomy Profile: Nairoviridae 2024. J Gen Virol. 2024 04; 105(4).
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Kuhn JH, Adkins S, Brown K, de la Torre JC, Digiaro M, Hughes HR, Junglen S, Lambert AJ, Maes P, Marklewitz M, Palacios G, Sasaya T, Turina M, Zhang YZ. ICTV Virus Taxonomy Profile: Cruliviridae 2023. J Gen Virol. 2023 12; 104(12).
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Koonin EV, Krupovic M, Surachetpong W, Wolf YI, Kuhn JH. ICTV Virus Taxonomy Profile: Amnoonviridae 2023. J Gen Virol. 2023 10; 104(10).
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