 Cyclooxygenase Inhibitors
"Cyclooxygenase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.
| Descriptor ID |
D016861
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| MeSH Number(s) |
D27.505.519.389.310 D27.505.696.663.850.014.040.500.500 D27.505.954.158.030.500 D27.505.954.329.030.500
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| Concept/Terms |
Cyclooxygenase Inhibitors- Cyclooxygenase Inhibitors
- Inhibitors, Cyclo-Oxygenase
- Inhibitors, Cyclo Oxygenase
- Inhibitors, Cyclooxygenase
- Prostaglandin Synthesis Antagonists
- Antagonists, Prostaglandin Synthesis
- Inhibitors, Prostaglandin-Endoperoxide Synthase
- Inhibitors, Prostaglandin Endoperoxide Synthase
- Prostaglandin Endoperoxide Synthase Inhibitors
- Prostaglandin Synthase Inhibitors
- Cyclo-Oxygenase Inhibitors
- Cyclo Oxygenase Inhibitors
- Inhibitors, Prostaglandin Synthase
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Below are MeSH descriptors whose meaning is more general than "Cyclooxygenase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Cyclooxygenase Inhibitors".
This graph shows the total number of publications written about "Cyclooxygenase Inhibitors" by people in this website by year, and whether "Cyclooxygenase Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 3 | 4 | | 1997 | 1 | 2 | 3 | | 1999 | 3 | 2 | 5 | | 2000 | 1 | 0 | 1 | | 2002 | 1 | 2 | 3 | | 2003 | 4 | 0 | 4 | | 2004 | 2 | 1 | 3 | | 2005 | 0 | 2 | 2 | | 2006 | 3 | 1 | 4 | | 2007 | 1 | 1 | 2 | | 2008 | 1 | 1 | 2 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 1 | 2 | | 2012 | 1 | 1 | 2 | | 2013 | 1 | 1 | 2 | | 2014 | 2 | 0 | 2 | | 2021 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclooxygenase Inhibitors" by people in Profiles.
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Sallmon H, Delaney CA. Platelets and ductus arteriosus closure in neonates. Semin Perinatol. 2023 03; 47(2):151719.
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Schofield JR, Hughes HN, Birlea M, Hassell KL. A trial of antithrombotic therapy in patients with refractory migraine and antiphospholipid antibodies: A retrospective study of 75 patients. Lupus. 2021 Apr; 30(4):568-577.
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Qayyum R, Becker DM, Yanek LR, Faraday N, Vaidya D, Mathias R, Kral BG, Becker LC. Greater collagen-induced platelet aggregation following cyclooxygenase 1 inhibition predicts incident acute coronary syndromes. Clin Transl Sci. 2015 Feb; 8(1):17-22.
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DeMauro SB, Wright CJ. Acetaminophen: a possible alternative to ibuprofen in patent ductus arteriosus closure. J Pediatr. 2014 Jul; 165(1):209-10.
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Aldrovandi M, Hammond VJ, Podmore H, Hornshaw M, Clark SR, Marnett LJ, Slatter DA, Murphy RC, Collins PW, O'Donnell VB. Human platelets generate phospholipid-esterified prostaglandins via cyclooxygenase-1 that are inhibited by low dose aspirin supplementation. J Lipid Res. 2013 Nov; 54(11):3085-97.
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Shin DM, Zhang H, Saba NF, Chen AY, Nannapaneni S, Amin AR, M?ller S, Lewis M, Sica G, Kono S, Brandes JC, Grist WJ, Moreno-Williams R, Beitler JJ, Thomas SM, Chen Z, Shin HJ, Grandis JR, Khuri FR, Chen ZG. Chemoprevention of head and neck cancer by simultaneous blocking of epidermal growth factor receptor and cyclooxygenase-2 signaling pathways: preclinical and clinical studies. Clin Cancer Res. 2013 Mar 01; 19(5):1244-56.
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Fujii N, Reinke MC, Brunt VE, Minson CT. Impaired acetylcholine-induced cutaneous vasodilation in young smokers: roles of nitric oxide and prostanoids. Am J Physiol Heart Circ Physiol. 2013 Mar 01; 304(5):H667-73.
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O'Brien JH, Vanderlinden LA, Schedin PJ, Hansen KC. Rat mammary extracellular matrix composition and response to ibuprofen treatment during postpartum involution by differential GeLC-MS/MS analysis. J Proteome Res. 2012 Oct 05; 11(10):4894-905.
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Eckman DM, Gupta R, Rosenfeld CR, Morgan TM, Charles SM, Mertz H, Moore LG. Pregnancy increases myometrial artery myogenic tone via NOS- or COX-independent mechanisms. Am J Physiol Regul Integr Comp Physiol. 2012 Aug 15; 303(4):R368-75.
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Prage EB, Pawelzik SC, Busenlehner LS, Kim K, Morgenstern R, Jakobsson PJ, Armstrong RN. Location of inhibitor binding sites in the human inducible prostaglandin E synthase, MPGES1. Biochemistry. 2011 Sep 06; 50(35):7684-93.
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