Cholinesterase Inhibitors
"Cholinesterase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
Descriptor ID |
D002800
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MeSH Number(s) |
D27.505.519.389.275 D27.505.519.625.120.300 D27.505.696.577.120.300
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Concept/Terms |
Cholinesterase Inhibitors- Cholinesterase Inhibitors
- Inhibitors, Cholinesterase
- Anticholinesterase Drugs
- Drugs, Anticholinesterase
- Anticholinesterases
- Anticholinesterase Agents
- Agents, Anticholinesterase
- Anti-Cholinesterases
- Anti Cholinesterases
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Below are MeSH descriptors whose meaning is more general than "Cholinesterase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Cholinesterase Inhibitors".
This graph shows the total number of publications written about "Cholinesterase Inhibitors" by people in this website by year, and whether "Cholinesterase Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 | 1998 | 0 | 1 | 1 | 2001 | 0 | 1 | 1 | 2002 | 1 | 1 | 2 | 2003 | 1 | 0 | 1 | 2004 | 0 | 1 | 1 | 2005 | 2 | 0 | 2 | 2006 | 1 | 0 | 1 | 2011 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2016 | 1 | 1 | 2 | 2017 | 0 | 1 | 1 | 2018 | 1 | 1 | 2 | 2019 | 2 | 1 | 3 | 2020 | 0 | 1 | 1 | 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Cholinesterase Inhibitors" by people in Profiles.
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Li G, Freundlich RE, Gupta RK, Hayhurst CJ, Le CH, Martin BJ, Shotwell MS, Wanderer JP. Postoperative Pulmonary Complications' Association with Sugammadex versus Neostigmine: A Retrospective Registry Analysis. Anesthesiology. 2021 06 01; 134(6):862-873.
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Brawman-Mintzer O, Tang XC, Bizien M, Harvey PD, Horner MD, Arciniegas DB, Raskind M, Johnson-Greene L, Martineau RJ, Hamner M, Rodriguez-Suarez M, Jorge RE, McGarity S, Wortzel HS, Wei Y, Sindowski T, Mintzer J, Kindy AZ, Donovan K, Reda D. Rivastigmine Transdermal Patch Treatment for Moderate to Severe Cognitive Impairment in Veterans with Traumatic Brain Injury (RiVET Study): A Randomized Clinical Trial. J Neurotrauma. 2021 07 15; 38(14):1943-1952.
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McGuire JR, Bester SM, Guelta MA, Cheung J, Langley C, Winemiller MD, Bae SY, Funk V, Myslinski JM, Pegan SD, Height JJ. Structural and Biochemical Insights into the Inhibition of Human Acetylcholinesterase by G-Series Nerve Agents and Subsequent Reactivation by HI-6. Chem Res Toxicol. 2021 03 15; 34(3):804-816.
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Zhang L, Murata H, Amitai G, Smith PN, Matyjaszewski K, Russell AJ. Catalytic Detoxification of Organophosphorus Nerve Agents by Butyrylcholinesterase-Polymer-Oxime Bioscavengers. Biomacromolecules. 2020 09 14; 21(9):3867-3877.
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Krause M, McWilliams SK, Bullard KJ, Mayes LM, Jameson LC, Mikulich-Gilbertson SK, Fernandez-Bustamante A, Bartels K. Neostigmine Versus Sugammadex for Reversal of Neuromuscular Blockade and Effects on Reintubation for Respiratory Failure or Newly Initiated Noninvasive Ventilation: An Interrupted Time Series Design. Anesth Analg. 2020 07; 131(1):141-151.
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Kheterpal S, Vaughn MT, Dubovoy TZ, Shah NJ, Bash LD, Colquhoun DA, Shanks AM, Mathis MR, Soto RG, Bardia A, Bartels K, McCormick PJ, Schonberger RB, Saager L. Sugammadex versus Neostigmine for Reversal of Neuromuscular Blockade and Postoperative Pulmonary Complications (STRONGER): A Multicenter Matched Cohort Analysis. Anesthesiology. 2020 06; 132(6):1371-1381.
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Naveed M, Jamil LH, Fujii-Lau LL, Al-Haddad M, Buxbaum JL, Fishman DS, Jue TL, Law JK, Lee JK, Qumseya BJ, Sawhney MS, Thosani N, Storm AC, Calderwood AH, Khashab MA, Wani SB. American Society for Gastrointestinal Endoscopy guideline on the role of endoscopy in the management of acute colonic pseudo-obstruction and colonic volvulus. Gastrointest Endosc. 2020 02; 91(2):228-235.
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Gonzalez Garcia A, Tutmaher MS, Upadhyayula SR, Sanchez Russo R, Verma S. Novel PLEC gene variants causing congenital myasthenic syndrome. Muscle Nerve. 2019 12; 60(6):E40-E43.
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Mantri S, Fullard M, Gray SL, Weintraub D, Hubbard RA, Hennessy S, Willis AW. Patterns of Dementia Treatment and Frank Prescribing Errors in Older Adults With Parkinson Disease. JAMA Neurol. 2019 01 01; 76(1):41-49.
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Kumar A, Asghar S, Kavanagh R, Wicklund MP. Unique presentation of rapidly fluctuating symptoms in a child with congenital myasthenic syndrome due to RAPSN mutation. Muscle Nerve. 2018 10; 58(4):E23-E24.
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