 Cytochrome P-450 Enzyme Inhibitors
"Cytochrome P-450 Enzyme Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 ENZYMES.
| Descriptor ID |
D065607
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| MeSH Number(s) |
D27.505.389.500 D27.505.519.389.335
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| Concept/Terms |
Cytochrome P-450 Enzyme Inhibitors- Cytochrome P-450 Enzyme Inhibitors
- Cytochrome P 450 Enzyme Inhibitors
- P-450 Enzyme Inhibitors
- Enzyme Inhibitors, P-450
- Inhibitors, P-450 Enzyme
- P 450 Enzyme Inhibitors
- P450 Enzyme Inhibitors
- Enzyme Inhibitors, P450
- Inhibitors, P450 Enzyme
- Cytochrome P-450 Inhibitors
- Cytochrome P 450 Inhibitors
- Inhibitors, Cytochrome P-450
- P-450 Inhibitors, Cytochrome
Cytochrome P-450 Monooxygenase Inhibitors- Cytochrome P-450 Monooxygenase Inhibitors
- Cytochrome P 450 Monooxygenase Inhibitors
- Cytochrome P-450-Dependent Monooxygenase Inhibitors
- Cytochrome P 450 Dependent Monooxygenase Inhibitors
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Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 Enzyme Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 Enzyme Inhibitors".
This graph shows the total number of publications written about "Cytochrome P-450 Enzyme Inhibitors" by people in this website by year, and whether "Cytochrome P-450 Enzyme Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cytochrome P-450 Enzyme Inhibitors" by people in Profiles.
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Rathkopf DE, Smith MR, de Bono JS, Logothetis CJ, Shore ND, de Souza P, Fizazi K, Mulders PF, Mainwaring P, Hainsworth JD, Beer TM, North S, Fradet Y, Van Poppel H, Carles J, Flaig TW, Efstathiou E, Yu EY, Higano CS, Taplin ME, Griffin TW, Todd MB, Yu MK, Park YC, Kheoh T, Small EJ, Scher HI, Molina A, Ryan CJ, Saad F. Updated interim efficacy analysis and long-term safety of abiraterone acetate in metastatic castration-resistant prostate cancer patients without prior chemotherapy (COU-AA-302). Eur Urol. 2014 Nov; 66(5):815-25.
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Pakrasi PL, Jain AK. Cyclooxygenase-2-derived endogenous prostacyclin reduces apoptosis and enhances embryo viability in mouse. Prostaglandins Leukot Essent Fatty Acids. 2008 Jul-Aug; 79(1-2):27-33.
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Lampe JN, Atkins WM. Time-resolved fluorescence studies of heterotropic ligand binding to cytochrome P450 3A4. Biochemistry. 2006 Oct 10; 45(40):12204-15.
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Day BJ, Kariya C. A novel class of cytochrome P450 reductase redox cyclers: cationic manganoporphyrins. Toxicol Sci. 2005 May; 85(1):713-9.
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Jacobsen W, Christians U, Benet LZ. In vitro evaluation of the disposition of A novel cysteine protease inhibitor. Drug Metab Dispos. 2000 Nov; 28(11):1343-51.
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Jacobsen W, Kirchner G, Hallensleben K, Mancinelli L, Deters M, Hackbarth I, Baner K, Benet LZ, Sewing KF, Christians U. Small intestinal metabolism of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor lovastatin and comparison with pravastatin. J Pharmacol Exp Ther. 1999 Oct; 291(1):131-9.
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Soldner A, Christians U, Susanto M, Wacher VJ, Silverman JA, Benet LZ. Grapefruit juice activates P-glycoprotein-mediated drug transport. Pharm Res. 1999 Apr; 16(4):478-85.
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Kim RB, Wandel C, Leake B, Cvetkovic M, Fromm MF, Dempsey PJ, Roden MM, Belas F, Chaudhary AK, Roden DM, Wood AJ, Wilkinson GR. Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein. Pharm Res. 1999 Mar; 16(3):408-14.
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Lampen A, Christians U, Gonschior AK, Bader A, Hackbarth I, von Engelhardt W, Sewing KF. Metabolism of the macrolide immunosuppressant, tacrolimus, by the pig gut mucosa in the Ussing chamber. Br J Pharmacol. 1996 Apr; 117(8):1730-4.
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Lampen A, Christians U, Guengerich FP, Watkins PB, Kolars JC, Bader A, Gonschior AK, Dralle H, Hackbarth I, Sewing KF. Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability. Drug Metab Dispos. 1995 Dec; 23(12):1315-24.
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