 Polymyxin B
"Polymyxin B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic.
| Descriptor ID |
D011112
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| MeSH Number(s) |
D04.345.566.780.750 D10.477.750.750 D12.644.050.600.750 D12.644.641.780.750 D12.776.543.695.054.600.750
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Polymyxin B".
Below are MeSH descriptors whose meaning is more specific than "Polymyxin B".
This graph shows the total number of publications written about "Polymyxin B" by people in this website by year, and whether "Polymyxin B" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 | | 2000 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Polymyxin B" by people in Profiles.
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Ngo SY, Rabbat JC. Systemic IgE-mediated hypersensitivity reaction to topical polymyxin B. J Allergy Clin Immunol Pract. 2019 Feb; 7(2):734-735.
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Crawford RW, Keestra AM, Winter SE, Xavier MN, Tsolis RM, Tolstikov V, B?umler AJ. Very long O-antigen chains enhance fitness during Salmonella-induced colitis by increasing bile resistance. PLoS Pathog. 2012 Sep; 8(9):e1002918.
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Guo J, Nair MK, Galv?n EM, Liu SL, Schifferli DM. Tn5AraOut mutagenesis for the identification of Yersinia pestis genes involved in resistance towards cationic antimicrobial peptides. Microb Pathog. 2011 Sep; 51(3):121-32.
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Hammond AA, Miller KG, Kruczek CJ, Dertien J, Colmer-Hamood JA, Griswold JA, Horswill AR, Hamood AN. An in vitro biofilm model to examine the effect of antibiotic ointments on biofilms produced by burn wound bacterial isolates. Burns. 2011 Mar; 37(2):312-21.
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Pilonieta MC, Erickson KD, Ernst RK, Detweiler CS. A protein important for antimicrobial peptide resistance, YdeI/OmdA, is in the periplasm and interacts with OmpD/NmpC. J Bacteriol. 2009 Dec; 191(23):7243-52.
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Erickson KD, Detweiler CS. The Rcs phosphorelay system is specific to enteric pathogens/commensals and activates ydeI, a gene important for persistent Salmonella infection of mice. Mol Microbiol. 2006 Nov; 62(3):883-94.
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Obritsch MD, Fish DN, MacLaren R, Jung R. Nosocomial infections due to multidrug-resistant Pseudomonas aeruginosa: epidemiology and treatment options. Pharmacotherapy. 2005 Oct; 25(10):1353-64.
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Gonzalez RJ, Moore EE, Biffl WL, Ciesla DJ, Silliman CC. The lipid fraction of post-hemorrhagic shock mesenteric lymph (PHSML) inhibits neutrophil apoptosis and enhances cytotoxic potential. Shock. 2000 Sep; 14(3):404-8.
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Pereira BJ, Sundaram S, Barrett TW, Butt NK, Porat R, King AJ, Dinarello CA. Transfer of cytokine-inducing bacterial products across hemodialyzer membranes in the presence of plasma or whole blood. Clin Nephrol. 1996 Dec; 46(6):394-401.
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Jagielo PJ, Thorne PS, Kern JA, Quinn TJ, Schwartz DA. Role of endotoxin in grain dust-induced lung inflammation in mice. Am J Physiol. 1996 Jun; 270(6 Pt 1):L1052-9.
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