 Receptors, Metabotropic Glutamate
"Receptors, Metabotropic Glutamate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins that bind glutamate and act through G-proteins to influence second messenger systems. Several types of metabotropic glutamate receptors have been cloned. They differ in pharmacology, distribution, and mechanisms of action.
| Descriptor ID |
D018094
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| MeSH Number(s) |
D12.776.543.750.695.450 D12.776.543.750.720.200.450.500
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| Concept/Terms |
Receptors, Metabotropic Glutamate- Receptors, Metabotropic Glutamate
- Metabotropic Glutamate Receptor
- Glutamate Receptor, Metabotropic
- Receptor, Metabotropic Glutamate
- Metabotropic Glutamate Receptors
- Receptors, Glutamate, Metabotropic
- Glutamate Receptors, Metabotropic
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Below are MeSH descriptors whose meaning is more general than "Receptors, Metabotropic Glutamate".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Metabotropic Glutamate".
This graph shows the total number of publications written about "Receptors, Metabotropic Glutamate" by people in this website by year, and whether "Receptors, Metabotropic Glutamate" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 2 | 0 | 2 | | 1998 | 0 | 1 | 1 | | 1999 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 2 | 0 | 2 | | 2009 | 1 | 2 | 3 | | 2010 | 2 | 1 | 3 | | 2011 | 0 | 2 | 2 | | 2012 | 2 | 1 | 3 | | 2013 | 2 | 0 | 2 | | 2014 | 4 | 1 | 5 | | 2015 | 2 | 0 | 2 | | 2016 | 1 | 0 | 1 | | 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Receptors, Metabotropic Glutamate" by people in Profiles.
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Cai Y, Ford CP. Dopamine Cells Differentially Regulate Striatal Cholinergic Transmission across Regions through Corelease of Dopamine and Glutamate. Cell Rep. 2018 12 11; 25(11):3148-3157.e3.
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Gates C, Backos DS, Reigan P, Kang HJ, Koerner C, Mirzaei J, Natale NR. Isoxazolo[3,4-d]pyridazinones positively modulate the metabotropic glutamate subtypes 2 and 4. Bioorg Med Chem. 2018 09 15; 26(17):4797-4803.
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Melroy-Greif WE, Vadasz C, Kamens HM, McQueen MB, Corley RP, Stallings MC, Hopfer CJ, Krauter KS, Brown SA, Hewitt JK, Ehringer MA. Test for association of common variants in GRM7 with alcohol consumption. Alcohol. 2016 09; 55:43-50.
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Gelb T, Pshenichkin S, Hathaway HA, Grajkowska E, Dalley CB, Wolfe BB, Wroblewski JT. Atypical signaling of metabotropic glutamate receptor 1 in human melanoma cells. Biochem Pharmacol. 2015 Nov 01; 98(1):182-9.
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Hathaway HA, Pshenichkin S, Grajkowska E, Gelb T, Emery AC, Wolfe BB, Wroblewski JT. Pharmacological characterization of mGlu1 receptors in cerebellar granule cells reveals biased agonism. Neuropharmacology. 2015 Jun; 93:199-208.
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Zak JD, Whitesell JD, Schoppa NE. Metabotropic glutamate receptors promote disinhibition of olfactory bulb glomeruli that scales with input strength. J Neurophysiol. 2015 Mar 15; 113(6):1907-20.
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Bernard PB, Castano AM, Bayer KU, Benke TA. Necessary, but not sufficient: insights into the mechanisms of mGluR mediated long-term depression from a rat model of early life seizures. Neuropharmacology. 2014 Sep; 84:1-12.
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Trinh MA, Ma T, Kaphzan H, Bhattacharya A, Antion MD, Cavener DR, Hoeffer CA, Klann E. The eIF2a kinase PERK limits the expression of hippocampal metabotropic glutamate receptor-dependent long-term depression. Learn Mem. 2014 Apr 16; 21(5):298-304.
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DiRaddo JO, Miller EJ, Hathaway HA, Grajkowska E, Wroblewska B, Wolfe BB, Liotta DC, Wroblewski JT. A real-time method for measuring cAMP production modulated by Gai/o-coupled metabotropic glutamate receptors. J Pharmacol Exp Ther. 2014 Jun; 349(3):373-82.
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Xie AX, Lauderdale K, Murphy T, Myers TL, Fiacco TA. Inducing plasticity of astrocytic receptors by manipulation of neuronal firing rates. J Vis Exp. 2014 Mar 20; (85).
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