 Orexin Receptors
"Orexin Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
G-protein-coupled NEUROPEPTIDE RECEPTORS that have specificity for OREXINS and play a role in appetite control, and sleep-wake cycles. Two principle receptor types exist, each having a specificity for OREXIN A and OREXIN B peptide subtypes.
| Descriptor ID |
D064446
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| MeSH Number(s) |
D12.776.543.750.695.023 D12.776.543.750.720.600.074 D12.776.543.750.750.555.074
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| Concept/Terms |
Orexin Receptors- Orexin Receptors
- Receptors, Orexin
- Hypocretin Receptors
- Receptors, Hypocretin
Orexin B Receptor- Orexin B Receptor
- Receptor, Orexin-B
- Receptor, Orexin B
- Orexin-B Receptors
- Orexin B Receptors
- Receptors, Orexin-B
- Orexin-B Receptor
- Orexin Receptor Type 2
- Receptor 2, Hypocretin
- HCTR2 Protein
- Protein, HCTR2
- Hypocretin Receptor 2
- Orexin Receptor 2
- Receptor 2, Orexin
- Hypocretin Receptors 2
- Receptors 2, Hypocretin
- Hypocretin-2 Receptor
- Hypocretin 2 Receptor
- Receptor, Hypocretin-2
- OX2 Receptors
- Receptors, OX2
- HCRT Receptor 2
- Receptor 2, HCRT
Orexin A Receptor- Orexin A Receptor
- Receptor, Orexin A
- Receptor, Orexin-A
- Hypocretin-1 Receptor
- Hypocretin 1 Receptor
- Receptor, Hypocretin-1
- Orexin-A Receptors
- Orexin A Receptors
- Receptors, Orexin-A
- Orexin Receptor Type 1
- HCRT Receptor 1
- Receptor 1, HCRT
- OX1 Receptors
- Receptors, OX1
- Orexin-A Receptor
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Below are MeSH descriptors whose meaning is more general than "Orexin Receptors".
Below are MeSH descriptors whose meaning is more specific than "Orexin Receptors".
This graph shows the total number of publications written about "Orexin Receptors" by people in this website by year, and whether "Orexin Receptors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 | | 2012 | 0 | 2 | 2 | | 2014 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Orexin Receptors" by people in Profiles.
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Neylan TC, Richards A, Metzler TJ, Ruoff LM, Varbel J, O'Donovan A, Sivasubramanian M, Motraghi T, Hlavin J, Batki SL, Inslicht SS, Samuelson K, Morairty SR, Kilduff TS. Acute cognitive effects of the hypocretin receptor antagonist almorexant relative to zolpidem and placebo: a randomized clinical trial. Sleep. 2020 10 13; 43(10).
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Terrill SJ, Hyde KM, Kay KE, Greene HE, Maske CB, Knierim AE, Davis JF, Williams DL. Ventral tegmental area orexin 1 receptors promote palatable food intake and oppose postingestive negative feedback. Am J Physiol Regul Integr Comp Physiol. 2016 09 01; 311(3):R592-9.
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Rorabaugh JM, Stratford JM, Zahniser NR. A relationship between reduced nucleus accumbens shell and enhanced lateral hypothalamic orexin neuronal activation in long-term fructose bingeing behavior. PLoS One. 2014; 9(4):e95019.
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Johnson PL, Samuels BC, Fitz SD, Federici LM, Hammes N, Early MC, Truitt W, Lowry CA, Shekhar A. Orexin 1 receptors are a novel target to modulate panic responses and the panic brain network. Physiol Behav. 2012 Dec 05; 107(5):733-42.
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Johnson PL, Samuels BC, Fitz SD, Lightman SL, Lowry CA, Shekhar A. Activation of the orexin 1 receptor is a critical component of CO2-mediated anxiety and hypertension but not bradycardia. Neuropsychopharmacology. 2012 Jul; 37(8):1911-22.
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Espa?a RA, Oleson EB, Locke JL, Brookshire BR, Roberts DC, Jones SR. The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine system. Eur J Neurosci. 2010 Jan; 31(2):336-48.
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