 Receptors, Bombesin
"Receptors, Bombesin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins that bind bombesin or closely related peptides with high affinity and trigger intracellular changes influencing the behavior of cells. Gastrin- releasing peptide (GRP); GRP 18-27 (neuromedin C), and neuromedin B are endogenous ligands of bombesin receptors in mammals.
| Descriptor ID |
D018004
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| MeSH Number(s) |
D12.776.543.750.695.070 D12.776.543.750.720.600.200 D12.776.543.750.750.555.200
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| Concept/Terms |
Receptors, Bombesin- Receptors, Bombesin
- Bombesin Receptors
- Gastrin-Releasing Peptide Receptor
- Gastrin Releasing Peptide Receptor
- Peptide Receptor, Gastrin-Releasing
- Receptor, Gastrin-Releasing Peptide
- Receptors, Neuromedin B
- Receptors, Gastrin-Releasing Peptide
- Receptors, Gastrin Releasing Peptide
- Neuromedin B Receptor
- B Receptor, Neuromedin
- Receptor, Neuromedin B
- Neuromedin B Receptors
- B Receptors, Neuromedin
- Bombesin Receptor
- Receptor, Bombesin
- Gastrin-Releasing Peptide Receptors
- Gastrin Releasing Peptide Receptors
- Peptide Receptors, Gastrin-Releasing
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Below are MeSH descriptors whose meaning is more general than "Receptors, Bombesin".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Bombesin [D12.776.543.750.695.070]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Bombesin [D12.776.543.750.720.600.200]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Bombesin [D12.776.543.750.750.555.200]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Bombesin".
This graph shows the total number of publications written about "Receptors, Bombesin" by people in this website by year, and whether "Receptors, Bombesin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Bombesin" by people in Profiles.
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Stott Reynolds TJ, Schehr R, Liu D, Xu J, Miao Y, Hoffman TJ, Rold TL, Lewis MR, Smith CJ. Characterization and evaluation of DOTA-conjugated Bombesin/RGD-antagonists for prostate cancer tumor imaging and therapy. Nucl Med Biol. 2015 Feb; 42(2):99-108.
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Mattei J, Achcar RD, Cano CH, Macedo BR, Meurer L, Batlle BS, Groshong SD, Kulczynski JM, Roesler R, Dal Lago L, Brunetto AT, Schwartsmann G. Gastrin-releasing peptide receptor expression in lung cancer. Arch Pathol Lab Med. 2014 Jan; 138(1):98-104.
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Durkan K, Jiang Z, Rold TL, Sieckman GL, Hoffman TJ, Bandari RP, Szczodroski AF, Liu L, Miao Y, Reynolds TS, Smith CJ. A heterodimeric [RGD-Glu-[(64)Cu-NO2A]-6-Ahx-RM2] av?3/GRPr-targeting antagonist radiotracer for PET imaging of prostate tumors. Nucl Med Biol. 2014 Feb; 41(2):133-9.
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Egloff AM, Gaither Davis A, Shuai Y, Land S, Pilewski JM, Luketich JD, Landreneau R, Miller YE, Grandis JR, Siegfried JM. Gastrin-releasing peptide receptor expression in non-cancerous bronchial epithelia is associated with lung cancer: a case-control study. Respir Res. 2012 Feb 01; 13:9.
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Chen X, Park R, Hou Y, Tohme M, Shahinian AH, Bading JR, Conti PS. microPET and autoradiographic imaging of GRP receptor expression with 64Cu-DOTA-[Lys3]bombesin in human prostate adenocarcinoma xenografts. J Nucl Med. 2004 Aug; 45(8):1390-7.
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Charlesworth A, Broad S, Rozengurt E. The bombesin/GRP receptor transfected into Rat-1 fibroblasts couples to phospholipase C activation, tyrosine phosphorylation of p125FAK and paxillin and cell proliferation. Oncogene. 1996 Mar 21; 12(6):1337-45.
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