 Receptors, Somatostatin
"Receptors, Somatostatin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins that bind somatostatin and trigger intracellular changes which influence the behavior of cells. Somatostatin is a hypothalamic hormone, a pancreatic hormone, and a central and peripheral neurotransmitter. Activated somatostatin receptors on pituitary cells inhibit the release of growth hormone; those on endocrine and gastrointestinal cells regulate the absorption and utilization of nutrients; and those on neurons mediate somatostatin's role as a neurotransmitter.
| Descriptor ID |
D017481
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| MeSH Number(s) |
D12.776.543.750.695.850 D12.776.543.750.720.600.760 D12.776.543.750.750.555.760 D12.776.543.750.750.580.720 D12.776.543.750.750.700.800
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| Concept/Terms |
Receptors, Somatostatin- Receptors, Somatostatin
- Somatostatin Receptors
- SRIH Receptors
- Receptors, Somatotropin Release Inhibiting Hormone
- Receptors, SRIH
- Somatostatin Receptor
- Receptor, Somatostatin
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Below are MeSH descriptors whose meaning is more general than "Receptors, Somatostatin".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Somatostatin [D12.776.543.750.695.850]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Somatostatin [D12.776.543.750.720.600.760]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Somatostatin [D12.776.543.750.750.555.760]
- Receptors, Pancreatic Hormone [D12.776.543.750.750.580]
- Receptors, Somatostatin [D12.776.543.750.750.580.720]
- Receptors, Pituitary Hormone-Regulating Hormone [D12.776.543.750.750.700]
- Receptors, Somatostatin [D12.776.543.750.750.700.800]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Somatostatin".
This graph shows the total number of publications written about "Receptors, Somatostatin" by people in this website by year, and whether "Receptors, Somatostatin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Somatostatin" by people in Profiles.
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Szidonya L, Park EA, Kwak JJ, Mallak N. Molecular and Anatomic Imaging of Neuroendocrine Tumors. Surg Oncol Clin N Am. 2022 10; 31(4):649-671.
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Kiseljak-Vassiliades K, Xu M, Mills TS, Smith EE, Silveira LJ, Lillehei KO, Kerr JM, Kleinschmidt-DeMasters BK, Wierman ME. Differential somatostatin receptor (SSTR) 1-5 expression and downstream effectors in histologic subtypes of growth hormone pituitary tumors. Mol Cell Endocrinol. 2015 Dec 05; 417:73-83.
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Spitsin S, Tuluc F, Meshki J, Ping Lai J, Tustin Iii R, Douglas SD. Analog of somatostatin vapreotide exhibits biological effects in vitro via interaction with neurokinin-1 receptor. Neuroimmunomodulation. 2013; 20(5):247-55.
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Bigott-Hennkens HM, Dannoon SF, Noll SM, Ruthengael VC, Jurisson SS, Lewis MR. Labeling, stability and biodistribution studies of 99mTc-cyclized Tyr3-octreotate derivatives. Nucl Med Biol. 2011 May; 38(4):549-55.
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Sutton BS, Palmer ND, Langefeld CD, Xue B, Proctor A, Ziegler JT, Haffner SM, Norris JM, Bowden DW. Association of SSTR2 polymorphisms and glucose homeostasis phenotypes: the Insulin Resistance Atherosclerosis Family Study. Diabetes. 2009 Jun; 58(6):1457-62.
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Edwards WB, Xu B, Akers W, Cheney PP, Liang K, Rogers BE, Anderson CJ, Achilefu S. Agonist-antagonist dilemma in molecular imaging: evaluation of a monomolecular multimodal imaging agent for the somatostatin receptor. Bioconjug Chem. 2008 Jan; 19(1):192-200.
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Salvatori R, Fintini D, Westra WH, Cho SY, Schulick RD. Cushing's Syndrome attributable to ectopic secretion of corticotropin in a patient with two neuroendocrine tumors. Endocr Pract. 2006 Nov-Dec; 12(6):656-9.
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Brinkmeier ML, Stahl JH, Gordon DF, Ross BD, Sarapura VD, Dowding JM, Kendall SK, Lloyd RV, Ridgway EC, Camper SA. Thyroid hormone-responsive pituitary hyperplasia independent of somatostatin receptor 2. Mol Endocrinol. 2001 Dec; 15(12):2129-36.
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Curtis SB, Chen JC, Winkelaar G, Turnbull RG, Hewitt J, Buchan AM, Hsiang YN. Effect of endothelial and adventitial injury on somatostatin receptor expression. Surgery. 2000 May; 127(5):577-83.
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Lin K, Nguyen BD, Ettinger DS, Chin BB. Somatostatin receptor scintigraphy and somatostatin therapy in the evaluation and treatment of malignant thymoma. Clin Nucl Med. 1999 Jan; 24(1):24-8.
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