 Epistasis, Genetic
"Epistasis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of gene interaction whereby the expression of one gene interferes with or masks the expression of a different gene or genes. Genes whose expression interferes with or masks the effects of other genes are said to be epistatic to the effected genes. Genes whose expression is affected (blocked or masked) are hypostatic to the interfering genes.
| Descriptor ID |
D004843
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| MeSH Number(s) |
G05.308.207
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| Concept/Terms |
Epistasis, Genetic- Epistasis, Genetic
- Epistases, Genetic
- Gene-Gene Interactions, Epistatic
- Gene Gene Interactions, Epistatic
- Gene-Gene Interaction, Epistatic
- Epistatic Gene-Gene Interaction
- Epistatic Gene-Gene Interactions
- Gene Gene Interaction, Epistatic
- Interaction, Epistatic Gene-Gene
- Interactions, Epistatic Gene-Gene
- Non-Allelic Gene Interactions
- Gene Interaction, Non-Allelic
- Gene Interactions, Non-Allelic
- Interaction, Non-Allelic Gene
- Interactions, Non-Allelic Gene
- Non Allelic Gene Interactions
- Non-Allelic Gene Interaction
- Genetic Epistasis
- Genetic Epistases
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Below are MeSH descriptors whose meaning is more general than "Epistasis, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Epistasis, Genetic".
This graph shows the total number of publications written about "Epistasis, Genetic" by people in this website by year, and whether "Epistasis, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2006 | 0 | 2 | 2 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 4 | 4 | | 2010 | 4 | 1 | 5 | | 2011 | 1 | 2 | 3 | | 2012 | 1 | 1 | 2 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 1 | 2 | | 2015 | 2 | 2 | 4 | | 2016 | 1 | 1 | 2 | | 2018 | 1 | 1 | 2 | | 2019 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Epistasis, Genetic" by people in Profiles.
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Rosser N, Edelman NB, Queste LM, Nelson M, Seixas F, Dasmahapatra KK, Mallet J. Complex basis of hybrid female sterility and Haldane's rule in Heliconius butterflies: Z-linkage and epistasis. Mol Ecol. 2022 02; 31(3):959-977.
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Semenov GA, Linck E, Enbody ED, Harris RB, Khaydarov DR, Alström P, Andersson L, Taylor SA. Asymmetric introgression reveals the genetic architecture of a plumage trait. Nat Commun. 2021 02 15; 12(1):1019.
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Liu Y, Huang J, Urbanowicz RJ, Chen K, Manduchi E, Greene CS, Moore JH, Scheet P, Chen Y. Embracing study heterogeneity for finding genetic interactions in large-scale research consortia. Genet Epidemiol. 2020 01; 44(1):52-66.
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Zukowski A, Phillips J, Park S, Wu R, Gygi SP, Johnson AM. Proteomic profiling of yeast heterochromatin connects direct physical and genetic interactions. Curr Genet. 2019 Apr; 65(2):495-505.
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Donaghey J, Thakurela S, Charlton J, Chen JS, Smith ZD, Gu H, Pop R, Clement K, Stamenova EK, Karnik R, Kelley DR, Gifford CA, Cacchiarelli D, Rinn JL, Gnirke A, Ziller MJ, Meissner A. Genetic determinants and epigenetic effects of pioneer-factor occupancy. Nat Genet. 2018 02; 50(2):250-258.
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De R, Verma SS, Holzinger E, Hall M, Burt A, Carrell DS, Crosslin DR, Jarvik GP, Kuivaniemi H, Kullo IJ, Lange LA, Lanktree MB, Larson EB, North KE, Reiner AP, Tragante V, Tromp G, Wilson JG, Asselbergs FW, Drenos F, Moore JH, Ritchie MD, Keating B, Gilbert-Diamond D. Identifying gene-gene interactions that are highly associated with four quantitative lipid traits across multiple cohorts. Hum Genet. 2017 02; 136(2):165-178.
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Baghel R, Grover S, Kaur H, Jajodia A, Parween S, Sinha J, Srivastava A, Srivastava AK, Bala K, Chandna P, Kushwaha S, Agarwal R, Kukreti R. Synergistic association of STX1A and VAMP2 with cryptogenic epilepsy in North Indian population. Brain Behav. 2016 07; 6(7):e00490.
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Ali Z, Waseem M, Kumar R, Pandey P, Mohammad G, Qadar Pasha MA. Unveiling the interactions among BMPR-2, ALK-1 and 5-HTT genes in the pathophysiology of HAPE. Gene. 2016 Aug 22; 588(2):163-72.
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Powers NR, Eicher JD, Miller LL, Kong Y, Smith SD, Pennington BF, Willcutt EG, Olson RK, Ring SM, Gruen JR. The regulatory element READ1 epistatically influences reading and language, with both deleterious and protective alleles. J Med Genet. 2016 Mar; 53(3):163-71.
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Daya M, van der Merwe L, van Helden PD, Möller M, Hoal EG. Investigating the Role of Gene-Gene Interactions in TB Susceptibility. PLoS One. 2014; 10(4):e0123970.
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