 Introns
"Introns" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Sequences of DNA in the genes that are located between the EXONS. They are transcribed along with the exons but are removed from the primary gene transcript by RNA SPLICING to leave mature RNA. Some introns code for separate genes.
| Descriptor ID |
D007438
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| MeSH Number(s) |
G05.360.340.024.220.400 G05.360.340.024.340.137.515
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| Concept/Terms |
Introns- Introns
- Intron
- Sequences, Intervening
- Intervening Sequence
- Sequence, Intervening
- Intervening Sequences
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Below are MeSH descriptors whose meaning is more general than "Introns".
Below are MeSH descriptors whose meaning is more specific than "Introns".
This graph shows the total number of publications written about "Introns" by people in this website by year, and whether "Introns" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 3 | 4 | | 1993 | 1 | 4 | 5 | | 1994 | 5 | 4 | 9 | | 1995 | 4 | 7 | 11 | | 1996 | 4 | 5 | 9 | | 1997 | 4 | 7 | 11 | | 1998 | 1 | 6 | 7 | | 1999 | 0 | 5 | 5 | | 2000 | 0 | 3 | 3 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 4 | 5 | | 2003 | 0 | 5 | 5 | | 2004 | 2 | 6 | 8 | | 2005 | 1 | 2 | 3 | | 2006 | 0 | 4 | 4 | | 2007 | 3 | 3 | 6 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 3 | 4 | | 2010 | 1 | 2 | 3 | | 2011 | 0 | 8 | 8 | | 2012 | 0 | 2 | 2 | | 2013 | 0 | 5 | 5 | | 2014 | 3 | 3 | 6 | | 2015 | 0 | 8 | 8 | | 2016 | 0 | 4 | 4 | | 2017 | 0 | 2 | 2 | | 2018 | 1 | 2 | 3 | | 2019 | 2 | 1 | 3 | | 2020 | 0 | 2 | 2 | | 2021 | 1 | 2 | 3 | | 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Introns" by people in Profiles.
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Bachu VS, Kandoi S, Park KU, Kaufman ML, Schwanke M, Lamba DA, Brzezinski JA. An enhancer located in a Pde6c intron drives transient expression in the cone photoreceptors of developing mouse and human retinas. Dev Biol. 2022 08; 488:131-150.
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Carranza F, Shenasa H, Hertel KJ. Splice site proximity influences alternative exon definition. RNA Biol. 2022 01; 19(1):829-840.
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Pinto EM, Maxwell KN, Halalsheh H, Phillips A, Powers J, MacFarland S, Walsh MF, Breen K, Formiga MN, Kriwacki R, Nichols KE, Mostafavi R, Wang J, Clay MR, Rodriguez-Galindo C, Ribeiro RC, Zambetti GP. Clinical and Functional Significance of TP53 Exon 4-Intron 4 Splice Junction Variants. Mol Cancer Res. 2022 02; 20(2):207-216.
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Danis D, Jacobsen JOB, Carmody LC, Gargano MA, McMurry JA, Hegde A, Haendel MA, Valentini G, Smedley D, Robinson PN. Interpretable prioritization of splice variants in diagnostic next-generation sequencing. Am J Hum Genet. 2021 09 02; 108(9):1564-1577.
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Dumbovic G, Braunschweig U, Langner HK, Smallegan M, Biayna J, Hass EP, Jastrzebska K, Blencowe B, Cech TR, Caruthers MH, Rinn JL. Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention. Nat Commun. 2021 06 03; 12(1):3308.
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Saldi T, Riemondy K, Erickson B, Bentley DL. Alternative RNA structures formed during transcription depend on elongation rate and modify RNA processing. Mol Cell. 2021 04 15; 81(8):1789-1801.e5.
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Pirim D, Bunker CH, Hokanson JE, Hamman RF, Demirci FY, Kamboh MI. Hepatic lipase (LIPC) sequencing in individuals with extremely high and low high-density lipoprotein cholesterol levels. PLoS One. 2020; 15(12):e0243919.
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Richard MA, Lupo PJ, Morton LM, Yasui YA, Sapkota YA, Arnold MA, Aubert G, Neglia JP, Turcotte LM, Leisenring WM, Sampson JN, Chanock SJ, Hudson MM, Armstrong GT, Robison LL, Bhatia S, Gramatges MM. Genetic variation in POT1 and risk of thyroid subsequent malignant neoplasm: A report from the Childhood Cancer Survivor Study. PLoS One. 2020; 15(2):e0228887.
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Li X, Liu S, Zhang L, Issaian A, Hill RC, Espinosa S, Shi S, Cui Y, Kappel K, Das R, Hansen KC, Zhou ZH, Zhao R. A unified mechanism for intron and exon definition and back-splicing. Nature. 2019 09; 573(7774):375-380.
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Szczesniak MW, Wanowska E, Mukherjee N, Ohler U, Makalowska I. Towards a deeper annotation of human lncRNAs. Biochim Biophys Acta Gene Regul Mech. 2020 04; 1863(4):194385.
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