 Internal Ribosome Entry Sites
"Internal Ribosome Entry Sites" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Sequences within MESSENGER RNA that enable PROTEIN TRANSLATION INITIATION independent of 5' CAPPED RNA.
| Descriptor ID |
D000067556
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| MeSH Number(s) |
D13.444.735.790.878.942.250 G02.111.570.080.689.687.093 G05.360.080.689.687.093
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Internal Ribosome Entry Sites".
Below are MeSH descriptors whose meaning is more specific than "Internal Ribosome Entry Sites".
This graph shows the total number of publications written about "Internal Ribosome Entry Sites" by people in this website by year, and whether "Internal Ribosome Entry Sites" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 2 | 0 | 2 | | 2016 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Internal Ribosome Entry Sites" by people in Profiles.
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Akirtava C, May GE, McManus CJ. False-positive IRESes from Hoxa9 and other genes resulting from errors in mammalian 5' UTR annotations. Proc Natl Acad Sci U S A. 2022 09 06; 119(36):e2122170119.
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Abaeva IS, Vicens Q, Bochler A, Soufari H, Simonetti A, Pestova TV, Hashem Y, Hellen CUT. The Halastavi ?rva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism. Cell Rep. 2020 12 08; 33(10):108476.
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Gross L, Vicens Q, Einhorn E, Noireterre A, Schaeffer L, Kuhn L, Imler JL, Eriani G, Meignin C, Martin F. The IRES5'UTR of the dicistrovirus cricket paralysis virus is a type III IRES containing an essential pseudoknot structure. Nucleic Acids Res. 2017 Sep 06; 45(15):8993-9004.
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Jaafar ZA, Oguro A, Nakamura Y, Kieft JS. Translation initiation by the hepatitis C virus IRES requires eIF1A and ribosomal complex remodeling. Elife. 2016 12 23; 5.
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Khong A, Bonderoff JM, Spriggs RV, Tammpere E, Kerr CH, Jackson TJ, Willis AE, Jan E. Temporal Regulation of Distinct Internal Ribosome Entry Sites of the Dicistroviridae Cricket Paralysis Virus. Viruses. 2016 Jan 19; 8(1).
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Ruehle MD, Zhang H, Sheridan RM, Mitra S, Chen Y, Gonzalez RL, Cooperman BS, Kieft JS. A dynamic RNA loop in an IRES affects multiple steps of elongation factor-mediated translation initiation. Elife. 2015 Nov 02; 4.
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Alberti MO, Jones JJ, Miglietta R, Ding H, Bakshi RK, Edmonds TG, Kappes JC, Ochsenbauer C. Optimized Replicating Renilla Luciferase Reporter HIV-1 Utilizing Novel Internal Ribosome Entry Site Elements for Native Nef Expression and Function. AIDS Res Hum Retroviruses. 2015 Dec; 31(12):1278-96.
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