 Toll-Like Receptor 7
"Toll-Like Receptor 7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pattern recognition receptor that binds several forms of imidazo-quinoline including the antiviral compound Imiquimod.
| Descriptor ID |
D051199
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| MeSH Number(s) |
D12.776.543.750.705.910.500.700
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptor 7".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptor 7".
This graph shows the total number of publications written about "Toll-Like Receptor 7" by people in this website by year, and whether "Toll-Like Receptor 7" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 2 | 2 | | 2006 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2010 | 2 | 1 | 3 | | 2011 | 2 | 0 | 2 | | 2012 | 0 | 1 | 1 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 1 | 2 | | 2016 | 1 | 1 | 2 | | 2020 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 | | 2024 | 0 | 1 | 1 | | 2025 | 1 | 2 | 3 |
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Below are the most recent publications written about "Toll-Like Receptor 7" by people in Profiles.
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Alexander BN, Kim S, Wells KL, Hunter MJ, Toole KP, Wemlinger SM, Regan DP, Getahun A, Smith MJ. Deletion of Ptpn2 in B cells promotes autoimmunity via TLR and JAK/STAT signaling. JCI Insight. 2025 Dec 22; 10(24).
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Graham-Gurysh EG, Woodring RN, Simpson SR, Mendell SE, Lukesh NR, Pena ES, Moore KM, Ontiveros-Padilla LA, Hendricksen AT, Lopez AM, Williamson GL, Murphy CT, Genito CJ, Hipp KA, Singh G, Zamboni WC, Hingtgen SD, Fecci PE, Bachelder EM, Ainslie KM. Post-resection delivery of a TLR7/8 agonist from a biodegradable scaffold achieves immune-mediated glioblastoma clearance and protection against tumor challenge in mice. Nat Commun. 2025 Sep 29; 16(1):8603.
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Rice MR, Matta B, Wang L, Luo Q, De Guzman J, Srinivasan D, Ludwig KR, Indukuri S, Brune L, Tan SL, Barnes BJ. TLR-induced STK25 activation promotes IRF5-mediated inflammation. Life Sci Alliance. 2025 Sep; 8(9).
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Luo Y, Su B, Hung V, Luo Y, Shi Y, Wang G, de Graaf D, Dinarello CA, Spaner DE. IL-1 receptor antagonism reveals a yin-yang relationship between NF?B and interferon signaling in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A. 2024 Aug 13; 121(33):e2405644121.
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Butler-Laporte G, Povysil G, Kosmicki JA, Cirulli ET, Drivas T, Furini S, Saad C, Schmidt A, Olszewski P, Korotko U, Quinodoz M, Çelik E, Kundu K, Walter K, Jung J, Stockwell AD, Sloofman LG, Jordan DM, Thompson RC, Del Valle D, Simons N, Cheng E, Sebra R, Schadt EE, Kim-Schulze S, Gnjatic S, Merad M, Buxbaum JD, Beckmann ND, Charney AW, Przychodzen B, Chang T, Pottinger TD, Shang N, Brand F, Fava F, Mari F, Chwialkowska K, Niemira M, Pula S, Baillie JK, Stuckey A, Salas A, Bello X, Pardo-Seco J, Gómez-Carballa A, Rivero-Calle I, Martinón-Torres F, Ganna A, Karczewski KJ, Veerapen K, Bourgey M, Bourque G, Eveleigh RJ, Forgetta V, Morrison D, Langlais D, Lathrop M, Mooser V, Nakanishi T, Frithiof R, Hultström M, Lipcsey M, Marincevic-Zuniga Y, Nordlund J, Schiabor Barrett KM, Lee W, Bolze A, White S, Riffle S, Tanudjaja F, Sandoval E, Neveux I, Dabe S, Casadei N, Motameny S, Alaamery M, Massadeh S, Aljawini N, Almutairi MS, Arabi YM, Alqahtani SA, Al Harthi FS, Almutairi A, Alqubaishi F, Alotaibi S, Binowayn A, Alsolm EA, El Bardisy H, Fawzy M, Cai F, Soranzo N, Butterworth A, Geschwind DH, Arteaga S, Stephens A, Butte MJ, Boutros PC, Yamaguchi TN, Tao S, Eng S, Sanders T, Tung PJ, Broudy ME, Pan Y, Gonzalez A, Chavan N, Johnson R, Pasaniuc B, Yaspan B, Smieszek S, Rivolta C, Bibert S, Bochud PY, Dabrowski M, Zawadzki P, Sypniewski M, Kaja E, Chariyavilaskul P, Nilaratanakul V, Hirankarn N, Shotelersuk V, Pongpanich M, Phokaew C, Chetruengchai W, Tokunaga K, Sugiyama M, Kawai Y, Hasegawa T, Naito T, Namkoong H, Edahiro R, Kimura A, Ogawa S, Kanai T, Fukunaga K, Okada Y, Imoto S, Miyano S, Mangul S, Abedalthagafi MS, Zeberg H, Grzymski JJ, Washington NL, Ossowski S, Ludwig KU, Schulte EC, Riess O, Moniuszko M, Kwasniewski M, Mbarek H, Ismail SI, Verma A, Goldstein DB, Kiryluk K, Renieri A, Ferreira MAR, Richards JB. Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative. PLoS Genet. 2022 11; 18(11):e1010367.
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Szeto MD, Maghfour J, Sivesind TE, Anderson J, Olayinka JT, Mamo A, Runion TM, Dellavalle RP. Interferon and Toll-Like Receptor 7 Response in COVID-19: Implications of Topical Imiquimod for Prophylaxis and Treatment. Dermatology. 2021; 237(6):847-856.
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Avcilar H, Eken A. Could imiquimod (Aldara 5% cream) or other TLR7 agonists be used in the treatment of COVID-19? Med Hypotheses. 2020 Nov; 144:110202.
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Rubtsova K, Rubtsov AV, Halemano K, Li SX, Kappler JW, Santiago ML, Marrack P. T Cell Production of IFN? in Response to TLR7/IL-12 Stimulates Optimal B Cell Responses to Viruses. PLoS One. 2016; 11(11):e0166322.
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Larson SR, Atif SM, Gibbings SL, Thomas SM, Prabagar MG, Danhorn T, Leach SM, Henson PM, Jakubzick CV. Ly6C(+) monocyte efferocytosis and cross-presentation of cell-associated antigens. Cell Death Differ. 2016 06; 23(6):997-1003.
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Rubtsova K, Marrack P, Rubtsov AV. TLR7, IFN?, and T-bet: their roles in the development of ABCs in female-biased autoimmunity. Cell Immunol. 2015 Apr; 294(2):80-3.
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