 GATA1 Transcription Factor
"GATA1 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A GATA transcription factor that is specifically expressed in hematopoietic lineages and plays an important role in the CELL DIFFERENTIATION of ERYTHROID CELLS and MEGAKARYOCYTES.
| Descriptor ID |
D050982
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| MeSH Number(s) |
D12.776.260.235.500 D12.776.260.257.100 D12.776.930.216.500 D12.776.930.314.100
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| Concept/Terms |
GATA1 Transcription Factor- GATA1 Transcription Factor
- Transcription Factor, GATA1
- NF-E1 Erythroid-Specific Transcription Factor
- NF E1 Erythroid Specific Transcription Factor
- Transcription Factor NFE-1
- NFE-1, Transcription Factor
- Transcription Factor GATA1
- Factor GATA1, Transcription
- GATA1, Transcription Factor
- Globin Transcription Factor 1
- Nuclear Factor-Erythroid 1
- Nuclear Factor Erythroid 1
- Eryf1 Erythroid-Specific Transcription Factor
- Eryf1 Erythroid Specific Transcription Factor
- Erythroid Transcription Factor 1
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Below are MeSH descriptors whose meaning is more general than "GATA1 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "GATA1 Transcription Factor".
This graph shows the total number of publications written about "GATA1 Transcription Factor" by people in this website by year, and whether "GATA1 Transcription Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2005 | 1 | 1 | 2 | | 2007 | 2 | 0 | 2 | | 2014 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "GATA1 Transcription Factor" by people in Profiles.
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Evans EJ, DeGregori J. Dissecting stepwise mutational impairment of megakaryopoiesis in a model of Down syndrome-associated leukemia. J Clin Invest. 2022 07 15; 132(14).
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Petruk S, Mariani SA, De Dominici M, Porazzi P, Minieri V, Cai J, Iacovitti L, Flomenberg N, Calabretta B, Mazo A. Structure of Nascent Chromatin Is Essential for Hematopoietic Lineage Specification. Cell Rep. 2017 04 11; 19(2):295-306.
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Yin L, Lovell MA, Wilson ML, Wei Q, Liang X. Distinct GATA1 Point Mutations in Monozygotic Twins With Down Syndrome and Transient Abnormal Myelopoiesis From a Triplet Pregnancy: A Case Report and Review of Literature. Am J Clin Pathol. 2016 Dec; 146(6):753-759.
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Wilkinson-White L, Lester KL, Ripin N, Jacques DA, Mitchell Guss J, Matthews JM. GATA1 directly mediates interactions with closely spaced pseudopalindromic but not distantly spaced double GATA sites on DNA. Protein Sci. 2015 Oct; 24(10):1649-59.
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Lee Y, Ghosh D, Hardison RC, Zhang Y. MRHMMs: multivariate regression hidden Markov models and the variantS. Bioinformatics. 2014 Jun 15; 30(12):1755-6.
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An N, Lin YW, Mahajan S, Kellner JN, Wang Y, Li Z, Kraft AS, Kang Y. Pim1 serine/threonine kinase regulates the number and functions of murine hematopoietic stem cells. Stem Cells. 2013 Jun; 31(6):1202-12.
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Torchia EC, Boyd K, Rehg JE, Qu C, Baker SJ. EWS/FLI-1 induces rapid onset of myeloid/erythroid leukemia in mice. Mol Cell Biol. 2007 Nov; 27(22):7918-34.
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Pine SR, Guo Q, Yin C, Jayabose S, Druschel CM, Sandoval C. Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome. Blood. 2007 Sep 15; 110(6):2128-31.
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Sandoval C, Pine SR. Down syndrome and GATA1-related transient leukemia. J Pediatr. 2007 Mar; 150(3):e34.
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Pine SR, Guo Q, Yin C, Jayabose S, Levendoglu-Tugal O, Ozkaynak MF, Sandoval C. GATA1 as a new target to detect minimal residual disease in both transient leukemia and megakaryoblastic leukemia of Down syndrome. Leuk Res. 2005 Nov; 29(11):1353-6.
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