 GATA3 Transcription Factor
"GATA3 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A GATA transcription factor that is found predominately in LYMPHOID CELL precursors and has been implicated in the CELL DIFFERENTIATION of HELPER T-CELLS. Haploinsufficiency of GATA3 is associated with HYPOPARATHYROIDISM; SENSORINEURAL HEARING LOSS; and renal anomalies syndrome.
| Descriptor ID |
D050990
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| MeSH Number(s) |
D12.776.260.235.687 D12.776.260.257.300 D12.776.930.216.687 D12.776.930.314.300
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| Concept/Terms |
GATA3 Transcription Factor- GATA3 Transcription Factor
- Transcription Factor, GATA3
- Transcription Factor GATA3
- GATA3, Transcription Factor
- Nuclear Factor-Erythroid 1C
- Nuclear Factor Erythroid 1C
- GATA-3 Factors
- GATA 3 Factors
- NF-E1C Protein
- NF E1C Protein
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Below are MeSH descriptors whose meaning is more general than "GATA3 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "GATA3 Transcription Factor".
This graph shows the total number of publications written about "GATA3 Transcription Factor" by people in this website by year, and whether "GATA3 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2004 | 0 | 2 | 2 | | 2005 | 1 | 0 | 1 | | 2010 | 1 | 2 | 3 | | 2012 | 0 | 1 | 1 | | 2014 | 1 | 2 | 3 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 1 | 1 | 2 | | 2019 | 1 | 0 | 1 | | 2020 | 0 | 2 | 2 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "GATA3 Transcription Factor" by people in Profiles.
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Bianco G, Coto-Llerena M, Gallon J, Kancherla V, Taha-Mehlitz S, Marinucci M, Konantz M, Srivatsa S, Montazeri H, Panebianco F, Tirunagaru VG, De Menna M, Paradiso V, Ercan C, Dahmani A, Montaudon E, Beerenwinkel N, Kruithof-de Julio M, Terracciano LM, Lengerke C, Jeselsohn RM, Doebele RC, Bidard FC, Marangoni E, Ng CKY, Piscuoglio S. GATA3 and MDM2 are synthetic lethal in estrogen receptor-positive breast cancers. Commun Biol. 2022 04 19; 5(1):373.
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Abe M, Cox TC, Firulli AB, Kanai SM, Dahlka J, Lim KC, Engel JD, Clouthier DE. GATA3 is essential for separating patterning domains during facial morphogenesis. Development. 2021 09 01; 148(17).
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Lindholm KE, Moran CA. Primary Mammary-Like Carcinoma of the Lung: A Case Report of a Distinct Type of Primary Lung Carcinoma. Int J Surg Pathol. 2020 Sep; 28(6):663-667.
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Liu S, Sirohi K, Verma M, McKay J, Michalec L, Sripada A, Danhorn T, Rollins D, Good J, Gorska MM, Martin RJ, Alam R. Optimal identification of human conventional and nonconventional (CRTH2-IL7Ra-) ILC2s using additional surface markers. J Allergy Clin Immunol. 2020 08; 146(2):390-405.
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Patrick AE, Wang W, Brokamp E, Graham TB, Aune TM, Duis JB. Juvenile idiopathic arthritis associated with a mutation in GATA3. Arthritis Res Ther. 2019 06 25; 21(1):156.
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Tufa DM, Yingst AM, Shank T, Shim S, Trahan GD, Lake J, Woods R, Jones KL, Verneris MR. Transient Expression of GATA3 in Hematopoietic Stem Cells Facilitates Helper Innate Lymphoid Cell Differentiation. Front Immunol. 2019; 10:510.
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Olivas AD, Taxy J, Wolsky R, Antic T. Phyllodes Tumor of the Prostate With Epithelial Intestinal Metaplasia. Am J Surg Pathol. 2018 06; 42(6):836-839.
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Wright BL, Nguyen N, Shim KP, Masterson JC, Jacobsen EA, Ochkur SI, Lee JJ, Furuta GT. Increased GATA-3 and T-bet expression in eosinophilic esophagitis versus gastroesophageal reflux disease. J Allergy Clin Immunol. 2018 05; 141(5):1919-1921.e5.
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Cascio S, Medsger TA, Hawse WF, Watkins SC, Milcarek C, Moreland LW, Lafyatis RA, Fuschiotti P. 14-3-3z sequesters cytosolic T-bet, upregulating IL-13 levels in TC2 and CD8+ lymphocytes from patients with scleroderma. J Allergy Clin Immunol. 2018 07; 142(1):109-119.e6.
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Silver JS, Kearley J, Copenhaver AM, Sanden C, Mori M, Yu L, Pritchard GH, Berlin AA, Hunter CA, Bowler R, Erjefalt JS, Kolbeck R, Humbles AA. Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs. Nat Immunol. 2016 06; 17(6):626-35.
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