 Cell Dedifferentiation
"Cell Dedifferentiation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A reverse developmental process in which terminally differentiated cells with specialized functions revert back to a less differentiated stage within their own CELL LINEAGE.
| Descriptor ID |
D054337
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| MeSH Number(s) |
G04.148
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| Concept/Terms |
Cell Dedifferentiation- Cell Dedifferentiation
- Cell Dedifferentiations
- Dedifferentiations, Cell
- Dedifferentiation, Cell
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Below are MeSH descriptors whose meaning is more general than "Cell Dedifferentiation".
Below are MeSH descriptors whose meaning is more specific than "Cell Dedifferentiation".
This graph shows the total number of publications written about "Cell Dedifferentiation" by people in this website by year, and whether "Cell Dedifferentiation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 4 | 4 | | 2012 | 2 | 1 | 3 | | 2013 | 1 | 1 | 2 | | 2014 | 0 | 3 | 3 | | 2016 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 1 | 2 | 3 |
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Below are the most recent publications written about "Cell Dedifferentiation" by people in Profiles.
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Hudish LI, Reusch JE, Sussel L. ? Cell dysfunction during progression of metabolic syndrome to type 2 diabetes. J Clin Invest. 2019 10 01; 129(10):4001-4008.
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Bruns DR, Tatman PD, Kalkur RS, Brown RD, Stenmark KR, Buttrick PM, Walker LA. The right ventricular fibroblast secretome drives cardiomyocyte dedifferentiation. PLoS One. 2019; 14(8):e0220573.
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Malik F, Santiago T, Bahrami A, Davis E, McCarville B, Newman S, Azzato EM, Davidoff AM, Brennan R, Ellison DW, Clay MR. Dedifferentiation in SDH-Deficient Gastrointestinal Stromal Tumor: A Report With Histologic, Immunophenotypic, and Molecular Characterization. Pediatr Dev Pathol. 2019 Oct; 22(5):492-498.
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Jones JC, Brindley CD, Elder NH, Myers MG, Rajala MW, Dekaney CM, McNamee EN, Frey MR, Shroyer NF, Dempsey PJ. Cellular Plasticity of Defa4Cre-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury. Cell Mol Gastroenterol Hepatol. 2019; 7(3):533-554.
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Montford JR, Lehman AM, Scobey MS, Weiser-Evans MC, Nemenoff RA, Furgeson SB. Cytosolic phospholipase A2a increases proliferation and de-differentiation of human renal tubular epithelial cells. Prostaglandins Other Lipid Mediat. 2016 11; 126:1-8.
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Folias AE, Penaranda C, Su AL, Bluestone JA, Hebrok M. Aberrant innate immune activation following tissue injury impairs pancreatic regeneration. PLoS One. 2014; 9(7):e102125.
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Davies BW, Prescott CR, Said SA, Campana J, Atti?-Castro FA, Velasco E Cruz AA, Durairaj VD. Radiation-induced dedifferentiated chondrosarcoma with orbital invasion. Ophthalmic Plast Reconstr Surg. 2014 May-Jun; 30(3):205-8.
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Halban PA, Polonsky KS, Bowden DW, Hawkins MA, Ling C, Mather KJ, Powers AC, Rhodes CJ, Sussel L, Weir GC. ?-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. J Clin Endocrinol Metab. 2014 Jun; 99(6):1983-92.
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El-Gohary Y, Tulachan S, Wiersch J, Guo P, Welsh C, Prasadan K, Paredes J, Shiota C, Xiao X, Wada Y, Diaz M, Gittes G. A smad signaling network regulates islet cell proliferation. Diabetes. 2014 Jan; 63(1):224-36.
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White RA, Neiman JM, Reddi A, Han G, Birlea S, Mitra D, Dionne L, Fernandez P, Murao K, Bian L, Keysar SB, Goldstein NB, Song N, Bornstein S, Han Z, Lu X, Wisell J, Li F, Song J, Lu SL, Jimeno A, Roop DR, Wang XJ. Epithelial stem cell mutations that promote squamous cell carcinoma metastasis. J Clin Invest. 2013 Oct; 123(10):4390-404.
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