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Nikki Lynn Farnsworth

TitleAsst Professor Adjoint
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-BDC Basic Research
Email

    Collapse Biography 
    Collapse education and training
    Rensselaer Polytechnic Institute, Troy, NYBS05/2007Chemical Engineering
    University of Colorado Boulder, Boulder, COMS08/2009Chemical and Biological Engineering
    University of Colorado Boulder, Boulder, COPhD05/2012Chemical and Biological Engineering

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    R01DK137221     (FARNSWORTH, NIKKI L.)Jul 1, 2024 - Jun 30, 2029
    NIH
    The Role of the Pancreas Microenvironment in Regulating Islet Function and Survival in Type 1 Diabetes
    Role: Principal Investigator
    F32DK102276     (FARNSWORTH, NIKKI L.)Sep 5, 2014 - Sep 4, 2017
    NIH
    Regulation of islet gap junction coupling and function under inflammatory conditions
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. St Clair JR, Westacott MJ, Miranda J, Farnsworth NL, Kravets V, Schleicher WE, Dwulet JM, Levitt CH, Heintz A, Ludin NWF, Benninger RKP. Restoring connexin-36 function in diabetogenic environments precludes mouse and human islet dysfunction. J Physiol. 2023 09; 601(18):4053-4072. PMID: 37578890.
      View in: PubMed
    2. Farnsworth NL, Piscopio RA, Schleicher WE, Ramirez DG, Miranda JG, Benninger RKP. Modulation of Gap Junction Coupling Within the Islet of Langerhans During the Development of Type 1 Diabetes. Front Physiol. 2022; 13:913611. PMID: 35837011.
      View in: PubMed
    3. Corezola do Amaral ME, Kravets V, Dwulet JM, Farnsworth NL, Piscopio R, Schleicher WE, Miranda JG, Benninger RKP. Caloric restriction recovers impaired ?-cell-?-cell gap junction coupling, calcium oscillation coordination, and insulin secretion in prediabetic mice. Am J Physiol Endocrinol Metab. 2020 10 01; 319(4):E709-E720. PMID: 32830549.
      View in: PubMed
    4. Pe?a B, Maldonado M, Bonham AJ, Aguado BA, Dominguez-Alfaro A, Laughter M, Rowland TJ, Bardill J, Farnsworth NL, Alegret Ramon N, Taylor MRG, Anseth KS, Prato M, Shandas R, McKinsey TA, Park D, Mestroni L. Gold Nanoparticle-Functionalized Reverse Thermal Gel for Tissue Engineering Applications. ACS Appl Mater Interfaces. 2019 May 22; 11(20):18671-18680. PMID: 31021594.
      View in: PubMed
    5. Farnsworth NL, Walter R, Piscopio RA, Schleicher WE, Benninger RKP. Exendin-4 overcomes cytokine-induced decreases in gap junction coupling via protein kinase A and Epac2 in mouse and human islets. J Physiol. 2019 01; 597(2):431-447. PMID: 30412665.
      View in: PubMed
    6. Pe?a B, Bosi S, Aguado BA, Borin D, Farnsworth NL, Dobrinskikh E, Rowland TJ, Martinelli V, Jeong M, Taylor MRG, Long CS, Shandas R, Sbaizero O, Prato M, Anseth KS, Park D, Mestroni L. Injectable Carbon Nanotube-Functionalized Reverse Thermal Gel Promotes Cardiomyocytes Survival and Maturation. ACS Appl Mater Interfaces. 2017 Sep 20; 9(37):31645-31656. PMID: 28895403.
      View in: PubMed
    7. Westacott MJ, Farnsworth NL, St Clair JR, Poffenberger G, Heintz A, Ludin NW, Hart NJ, Powers AC, Benninger RKP. Age-Dependent Decline in the Coordinated [Ca2+] and Insulin Secretory Dynamics in Human Pancreatic Islets. Diabetes. 2017 09; 66(9):2436-2445. PMID: 28588099.
      View in: PubMed
    8. Farnsworth NL, Walter RL, Hemmati A, Westacott MJ, Benninger RK. Low Level Pro-inflammatory Cytokines Decrease Connexin36 Gap Junction Coupling in Mouse and Human Islets through Nitric Oxide-mediated Protein Kinase Cd. J Biol Chem. 2016 Feb 12; 291(7):3184-96. PMID: 26668311.
      View in: PubMed
    9. Farnsworth NL, Hemmati A, Pozzoli M, Benninger RK. Fluorescence recovery after photobleaching reveals regulation and distribution of connexin36 gap junction coupling within mouse islets of Langerhans. J Physiol. 2014 Oct 15; 592(20):4431-46. PMID: 25172942.
      View in: PubMed
    10. Farnsworth NL, Mead BE, Antunez LR, Palmer AE, Bryant SJ. Ionic osmolytes and intracellular calcium regulate tissue production in chondrocytes cultured in a 3D charged hydrogel. Matrix Biol. 2014 Nov; 40:17-26. PMID: 25128592.
      View in: PubMed
    11. Farnsworth NL, Benninger RK. New insights into the role of connexins in pancreatic islet function and diabetes. FEBS Lett. 2014 Apr 17; 588(8):1278-87. PMID: 24583073.
      View in: PubMed
    12. Farnsworth NL, Antunez LR, Bryant SJ. Dynamic compressive loading differentially regulates chondrocyte anabolic and catabolic activity with age. Biotechnol Bioeng. 2013 Jul; 110(7):2046-57. PMID: 23404228.
      View in: PubMed
    13. Farnsworth NL, Antunez LR, Bryant SJ. Influence of chondrocyte maturation on acute response to impact injury in PEG hydrogels. J Biomech. 2012 Oct 11; 45(15):2556-63. PMID: 22964019.
      View in: PubMed
    14. Farnsworth N, Bensard C, Bryant SJ. The role of the PCM in reducing oxidative stress induced by radical initiated photoencapsulation of chondrocytes in poly(ethylene glycol) hydrogels. Osteoarthritis Cartilage. 2012 Nov; 20(11):1326-35. PMID: 22796510.
      View in: PubMed
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