 ras Guanine Nucleotide Exchange Factors
"ras Guanine Nucleotide Exchange Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of GUANINE NUCLEOTIDE EXCHANGE FACTORS that are specific for RAS PROTEINS.
| Descriptor ID |
D020663
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| MeSH Number(s) |
D12.644.360.325.300.700 D12.776.476.325.300.700
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "ras Guanine Nucleotide Exchange Factors".
Below are MeSH descriptors whose meaning is more specific than "ras Guanine Nucleotide Exchange Factors".
This graph shows the total number of publications written about "ras Guanine Nucleotide Exchange Factors" by people in this website by year, and whether "ras Guanine Nucleotide Exchange Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "ras Guanine Nucleotide Exchange Factors" by people in Profiles.
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Wang Q, Siminovitch KA, Downey GP, McCulloch CA. Ras-guanine-nucleotide-releasing factors 1 and 2 interact with PLC? at focal adhesions to enable IL-1-induced Ca(2+) signalling, ERK activation and MMP-3 expression. Biochem J. 2013 Feb 01; 449(3):771-82.
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Hong J, Doebele RC, Lingen MW, Quilliam LA, Tang WJ, Rosner MR. Anthrax edema toxin inhibits endothelial cell chemotaxis via Epac and Rap1. J Biol Chem. 2007 Jul 06; 282(27):19781-7.
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Sasaoka T, Langlois WJ, Bai F, Rose DW, Leitner JW, Decker SJ, Saltiel A, Gill GN, Kobayashi M, Draznin B, Olefsky JM. Involvement of ErbB2 in the signaling pathway leading to cell cycle progression from a truncated epidermal growth factor receptor lacking the C-terminal autophosphorylation sites. J Biol Chem. 1996 Apr 05; 271(14):8338-44.
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Reusch JE, Bhuripanyo P, Carel K, Leitner JW, Hsieh P, DePaolo D, Draznin B. Differential requirement for p21ras activation in the metabolic signaling by insulin. J Biol Chem. 1995 Feb 03; 270(5):2036-40.
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Langlois WJ, Medh J, Leitner JW, Sasaoka T, Olefsky JM, Draznin B. Insulin and epidermal growth factor influence guanine nucleotide-releasing factor by distinct mechanisms. Endocrinology. 1994 Dec; 135(6):2412-7.
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Sasaoka T, Draznin B, Leitner JW, Langlois WJ, Olefsky JM. Shc is the predominant signaling molecule coupling insulin receptors to activation of guanine nucleotide releasing factor and p21ras-GTP formation. J Biol Chem. 1994 Apr 08; 269(14):10734-8.
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Draznin B, Chang L, Leitner JW, Takata Y, Olefsky JM. Insulin activates p21Ras and guanine nucleotide releasing factor in cells expressing wild type and mutant insulin receptors. J Biol Chem. 1993 Sep 25; 268(27):19998-20001.
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