 Receptors, Tumor Necrosis Factor, Member 14
"Receptors, Tumor Necrosis Factor, Member 14" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A novel member of the tumor-necrosis factor receptor family that can also mediate HERPES SIMPLEX VIRUS TYPE 1 entry into cells. It has specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 and the homotrimeric form of LYMPHOTOXIN-ALPHA. The receptor is abundantly expressed on T-LYMPHOCYTES and may play a role in regulating lymphocyte activation. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
| Descriptor ID |
D053240
|
| MeSH Number(s) |
D12.776.543.750.705.852.760.500 D12.776.543.750.830.850
|
| Concept/Terms |
Receptors, Tumor Necrosis Factor, Member 14- Receptors, Tumor Necrosis Factor, Member 14
- HveA Protein
- Tumor Necrosis Factor Receptor Superfamily, Member 14
- Tumor Necrosis Factor Receptor Subfamily, Member 14
- HVEM Protein
- Herpesvirus Entry Mediator
- Entry Mediator, Herpesvirus
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Tumor Necrosis Factor, Member 14".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Tumor Necrosis Factor [D12.776.543.750.705.852.760]
- Receptors, Tumor Necrosis Factor, Member 14 [D12.776.543.750.705.852.760.500]
- Receptors, Virus [D12.776.543.750.830]
- Receptors, Tumor Necrosis Factor, Member 14 [D12.776.543.750.830.850]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Tumor Necrosis Factor, Member 14".
This graph shows the total number of publications written about "Receptors, Tumor Necrosis Factor, Member 14" by people in this website by year, and whether "Receptors, Tumor Necrosis Factor, Member 14" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Tumor Necrosis Factor, Member 14" by people in Profiles.
-
Rosenbaum SR, Tiago M, Caksa S, Capparelli C, Purwin TJ, Kumar G, Glasheen M, Pomante D, Kotas D, Chervoneva I, Aplin AE. SOX10 requirement for melanoma tumor growth is due, in part, to immune-mediated effects. Cell Rep. 2021 12 07; 37(10):110085.
-
Ren S, Tian Q, Amar N, Yu H, Rivard CJ, Caldwell C, Ng TL, Tu M, Liu Y, Gao D, Ellison K, Suda K, Rozeboom L, Rivalland G, Mitchell P, Zhou C, Hirsch FR. The immune checkpoint, HVEM may contribute to immune escape in non-small cell lung cancer lacking PD-L1 expression. Lung Cancer. 2018 11; 125:115-120.
-
Patrusheva I, Perelygina L, Torshin I, LeCher J, Hilliard J. B Virus (Macacine Herpesvirus 1) Divergence: Variations in Glycoprotein D from Clinical and Laboratory Isolates Diversify Virus Entry Strategies. J Virol. 2016 10 15; 90(20):9420-32.
-
Zhu Y, Yao S, Augustine MM, Xu H, Wang J, Sun J, Broadwater M, Ruff W, Luo L, Zhu G, Tamada K, Chen L. Neuron-specific SALM5 limits inflammation in the CNS via its interaction with HVEM. Sci Adv. 2016 Apr; 2(4):e1500637.
-
Sakoda Y, Park JJ, Zhao Y, Kuramasu A, Geng D, Liu Y, Davila E, Tamada K. Dichotomous regulation of GVHD through bidirectional functions of the BTLA-HVEM pathway. Blood. 2011 Feb 24; 117(8):2506-14.
-
Anand S, Wang P, Yoshimura K, Choi IH, Hilliard A, Chen YH, Wang CR, Schulick R, Flies AS, Flies DB, Zhu G, Xu Y, Pardoll DM, Chen L, Tamada K. Essential role of TNF family molecule LIGHT as a cytokine in the pathogenesis of hepatitis. J Clin Invest. 2006 Apr; 116(4):1045-51.
-
Wang J, Anders RA, Wang Y, Turner JR, Abraham C, Pfeffer K, Fu YX. The critical role of LIGHT in promoting intestinal inflammation and Crohn's disease. J Immunol. 2005 Jun 15; 174(12):8173-82.
-
Wang Y, Subudhi SK, Anders RA, Lo J, Sun Y, Blink S, Wang Y, Wang J, Liu X, Mink K, Degrandi D, Pfeffer K, Fu YX. The role of herpesvirus entry mediator as a negative regulator of T cell-mediated responses. J Clin Invest. 2005 Mar; 115(3):711-7.
-
Yu P, Lee Y, Liu W, Chin RK, Wang J, Wang Y, Schietinger A, Philip M, Schreiber H, Fu YX. Priming of naive T cells inside tumors leads to eradication of established tumors. Nat Immunol. 2004 Feb; 5(2):141-9.
-
Wang J, Fu YX. The role of LIGHT in T cell-mediated immunity. Immunol Res. 2004; 30(2):201-14.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|